Satellite Symposium on Obesity and Endocrine Disruptors

肥胖与内分泌干扰物卫星研讨会

• 批准号: 8129105
• 负责人: Nira Ben-Jonathan
• 金额: $ 0.8万
• 依托单位: UNIVERSITY OF CINCINNATI
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-02-15 至 2012-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8129105
• 关键词: Accounting; Adult; Age; Area; Cardiovascular Diseases; Cardiovascular system; Cause of Death; Cessation of life; Chemical Exposure; Chemicals; Child; Child health care; Congresses; Cultured Cells; Developed Countries; Development; Diabetes Mellitus; Digestive System Disorders; Disease; Dose; Elderly; Endocrine Disruptors; Endocrinology; Environment; Environmental Health; Environmental Risk Factor; Epidemic; Etiology; Europe; European; Exercise; Exposure to; Gene Mutation; Hormonal; Human; Human Development; In Vitro; Institutes; International; Kidney Diseases; Laboratory Animals; Life; Link; Low Birth Weight Infant; Meleagris gallopavo; Metabolic syndrome; Molecular; National Heart, Lung, and Blood Institute; Non-Insulin-Dependent Diabetes Mellitus; Obesity; Obesity associated disease; Overweight; Pathology; Play; Predisposition; Prevalence; Process; Publishing; Research; Risk Assessment; Role; Scientist; Signal Transduction; Time; Toxicology; United States; United States National Institutes of Health; body system; environmental chemical; environmental chemical exposure; exposed human population; in vivo; interest; lectures; malformation; meetings; nutrition; symposium; unpublished works

DESCRIPTION (provided by applicant): A one day satellite symposium, entitled: "Role of Environmental Chemical Exposure in the Etiology of Obesity and the Metabolic Syndrome" will be held in May 24, 2011, in Istanbul, Turkey, in conjunction with the 18th Annual Meeting of the European Association for the Study of Obesity (EASO). The symposium includes 10 invited lectures on various aspects of endocrine disrupting chemicals (EDC) as they impact on obesity and its associated diseases, i.e., the metabolic syndrome, diabetes and cardiovascular complications. An audience of over 100 attendees is expected. The symposium is framed around the following Specific Aims: 1. To bring together national and international leaders in EDC research in a meeting format that promotes debate how to integrate research findings into the risk assessment process. 2. To present the latest developments, including unpublished work, in important areas in EDC research, emphasizing new directions that should guide future research in this area. 3. To discuss the action of endocrine disruptors on multiple organ systems, and the consequences of early and late life exposure, as well as transgenerational components, on the development of obesity and its sequalae. 4. To integrate the strength of evidence derived from studies with cultured cells, laboratory animals and humans, that links EDC exposure to obesity and the metabolic syndrome. 5. To encourage participation of trainees and other young scientists in EDC research. This symposium represents a timely opportunity to bring a very important issue to the forefront of obesity research. It provides venue for presentations by leaders in the field, with ample time for discussions and informal interactions. It is anticipated that a proceeding of the meeting will be published in Cellular and Molecular Endocrinology. The diverse topics and their translational implications that will be covered at this meeting should be of interest not only to the National Institute on Environmental Health Sciences (NIEHS), but also to other NIH institutes with vested interest in the obesity epidemics. These include the National Institute on Diabetes, Digestive and Kidney Disease (NIDDK), the National Heart, Lung and Blood Institute (NHLBI), and the National Institute of Child Health and Human Development (NICHD). PUBLIC HEALTH RELEVANCE: This is an R13 application to support a one day satellite symposium on the role of endocrine disruptors in the etiology of obesity and the metabolic syndrome. The meeting will be held on May 24, 2011 in Istanbul, Turkey in conjunction with the 17th European Congress on Obesity.

描述（由申请人提供）：将于2011年5月24日在土耳其伊斯坦布尔与欧洲肥胖研究协会（EASO）第18届年会一起举行为期一天的卫星研讨会，题为：“环境化学品暴露在肥胖和代谢综合征病因学中的作用”。研讨会包括10个关于内分泌干扰化学品（EDC）对肥胖及其相关疾病的影响的各个方面的特邀讲座，即，代谢综合征、糖尿病和心血管并发症。预计将有100多名与会者。本次研讨会围绕以下具体目标：1。将EDC研究的国家和国际领导人聚集在一起，以会议形式促进辩论如何将研究结果纳入风险评估过程。2.介绍EDC研究重要领域的最新进展，包括未发表的工作，强调应指导该领域未来研究的新方向。3.讨论内分泌干扰物对多器官系统的作用，以及早期和晚期生活暴露的后果，以及跨代成分对肥胖及其后遗症的发展。4.整合来自培养细胞、实验室动物和人类研究的证据，将EDC暴露与肥胖和代谢综合征联系起来。5.鼓励受训人员和其他年轻科学家参与EDC研究。这次研讨会是一个及时的机会，把一个非常重要的问题，肥胖研究的前沿。它为外地领导人的发言提供了场所，并有充足的时间进行讨论和非正式互动。预计会议记录将在《细胞和分子内分泌学》上发表。本次会议将涉及的各种主题及其翻译影响不仅应该引起美国国家环境健康科学研究所（NIEHS）的兴趣，而且应该引起其他NIH研究所对肥胖流行病的兴趣。这些机构包括国家糖尿病、消化和肾脏疾病研究所（NIDDK）、国家心脏、肺和血液研究所（NHLBI）以及国家儿童健康和人类发展研究所（NICHD）。 公共卫生相关性：这是一个R13应用程序，以支持为期一天的卫星研讨会上的作用，内分泌干扰物的病因肥胖和代谢综合征。会议将于2011年5月24日在土耳其伊斯坦布尔与第17届欧洲肥胖大会同时举行。

项目成果

Method for determining the lung burden of talc in rats and mice after inhalation exposure to talc aerosols.

大鼠和小鼠吸入暴露于滑石气溶胶后确定滑石粉肺负荷的方法。

• DOI: 10.1002/jat.2550050504
• 发表时间: 1985
• 期刊: Journal of applied toxicology : JAT
• 作者: Hanson,RL;Benson,JM;Henderson,TR;Carpenter,RL;Pickrell,JA;Brown,SC
• 通讯作者: Brown,SC

Talc deposition and effects after 20 days of repeated inhalation exposure of rats and mice to talc.

大鼠和小鼠重复吸入滑石粉 20 天后滑石粉沉积和影响。

• DOI: 10.1016/s0013-9351(89)80069-6
• 发表时间: 1989
• 期刊: Environmental research
• 影响因子: 8.3
• 作者: Pickrell,JA;Snipes,MB;Benson,JM;Hanson,RL;Jones,RK;Carpenter,RL;Thompson,JJ;Hobbs,CH;Brown,SC
• 通讯作者: Brown,SC