Advanced Training for Leadership in Urology and Urological Research

泌尿外科和泌尿外科研究领导力高级培训

• 批准号: 8107457
• 负责人: JEFFREY J LYSIAK
• 金额: $ 11.95万
• 依托单位: UNIVERSITY OF VIRGINIA
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-01 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8107457
• 关键词: Leadership; Research; Training; Urology; urologic

DESCRIPTION (provided by applicant): This application requests support for the training of basic scientists and board-eligible urologists for careers as independent investigators committed to the study of genitourinary biology and pathology. Diseases of the urogenital system affect over 50 million Americans. Training highly qualified physician-scientists and basic scientists in urogenital system research is an important national health need. The proposed training program will build on a history at the University of Virginia of training biomedical scientists and will develop scientists who will continue to meet the biomedical research challenges of the future, The program will equip both clinical and basic scientists with research experience using modern research tools and provide them with the knowledge base needed for the unraveling of urogenital disorders. The training program is tailored to accommodate doctoral-level candidates from diverse academic backgrounds, whether they be post-residency trainees (M.D.'s) or post-doctoral basic scientists (Ph.D.'s). Formal instruction will be available in subjects from biostatistics to cell and molecular biology. In addition, the trainees will participate in a UVA Certificate Program focusing on one of five different topic areas ranging from clinical research to public health, courses that can be used in pursuit of an M. P. H. degree. As "pre-faculty", our trainees will also have the unique opportunity to participate in the University of Virginia School of Medicine's Faculty Development Program which covers topics from grant writing, to resume building, to time and resource management. All mentors hold tenure-track appointments in the School of Medicine and are P.l.'s of at least one active grant relevant to the urogenital system. Each has significant experience with postdoctoral trainees. The institutional environment offers a rich mixture of seminars, visiting professors, and conferences. These create stimulating academic exchanges in preceptors' labs that have nationally recognized strengths in genitourinary system studies. Areas of interest to this application include NIH supported research into obstructive uropathy and renal development, the pharmacology of bladder and urogenital smooth muscle, testicular and epididymal function, sperm biology, and urologic oncology. It is the goal of this program to train both physicians and basic scientists for careers in urogenital investigation that will match or exceed those of their mentors.

描述（由申请人提供）： 该申请要求支持基础科学家和符合董事会资格的泌尿科医生的培训，以作为致力于泌尿生殖生物学和病理学研究的独立调查人员。泌尿生殖系统疾病影响超过5000万美国人。在泌尿生殖系统研究方面培养高素质的医生科学家和基础科学家是国家重要的卫生需求。拟议的培训计划将建立在弗吉尼亚大学培养生物医学科学家的历史基础上，并将培养将继续迎接未来生物医学研究挑战的科学家，该计划将为临床和基础科学家提供使用现代研究工具的研究经验，并为他们提供解决泌尿生殖系统疾病所需的知识基础。该培训计划是量身定制的，以适应来自不同学术背景的博士水平的候选人，无论他们是后住院实习生（医学博士，的）或博士后基础科学家（Ph.D.的）。从生物统计学到细胞和分子生物学，都将提供正式的指导。此外，学员将参加UVA证书课程，重点是从临床研究到公共卫生的五个不同主题领域之一，这些课程可用于追求M。P. H.℃下作为“预科教师”，我们的学员也将有独特的机会参加弗吉尼亚大学医学院的教师发展计划，该计划涵盖了从赠款写作，简历建设，时间和资源管理等主题。所有的导师都在医学院担任终身教职，并且是P.L.。至少有一项与泌尿生殖系统相关的活动资助。每个人都有丰富的博士后培训经验。机构环境提供了研讨会，访问教授和会议的丰富组合。这些创造了刺激的学术交流导师的实验室，具有全国公认的优势，在泌尿生殖系统的研究。感兴趣的领域，这一应用包括美国国立卫生研究院支持的研究梗阻性尿路病和肾脏发育，膀胱和泌尿生殖平滑肌，睾丸和附睾功能，精子生物学，泌尿肿瘤学的药理学。该计划的目标是培养医生和基础科学家在泌尿生殖系统调查的职业生涯，将匹配或超过他们的导师。

项目成果

Src and caveolin-1 reciprocally regulate metastasis via a common downstream signaling pathway in bladder cancer.

• DOI: 10.1158/0008-5472.can-10-0730
• 发表时间: 2011-02-01
• 期刊: Cancer research
• 影响因子: 11.2
• 作者: Thomas S;Overdevest JB;Nitz MD;Williams PD;Owens CR;Sanchez-Carbayo M;Frierson HF;Schwartz MA;Theodorescu D
• 通讯作者: Theodorescu D

Cytokine responses to E. coli-induced epididymitis in the rat: blockade by vasectomy.

细胞因子对大肠杆菌诱导的大鼠附睾炎的反应：输精管结扎术的阻断。

• DOI: 10.1016/j.urology.2011.02.037
• 发表时间: 2011
• 期刊: Urology
• 影响因子: 2.1
• 作者: Turner,TerryT;Mammen,Tony;Kavoussi,Parviz;Lysiak,JeffreyJ;Costabile,RaymondA
• 通讯作者: Costabile,RaymondA