Endocrine Scientists Training Program

描述(申请人提供)：内分泌和新陈代谢障碍在美国很普遍。解决这些困难的两难境地不仅需要培养一支足够多的医生来照顾受影响的患者，还需要培训熟练的研究人员，以开发创新的疗法和预防措施，并深入研究疾病的基本机制。印第安纳大学医学院在许多医学领域处于领先地位。它的儿科内分泌科和医学部的内分泌学和新陈代谢科都是备受尊敬的大型研究部门，都有长期指导博士后和博士后学员的历史，包括在跨越儿科和成人内分泌学范围的研究中相互培训研究员。这里介绍的内分泌科学家培训计划为参加儿科、成人或医学-儿科内分泌学联合培训的年轻科学家提供机会，以提高他们在基础实验室、临床或转化性研究方面的技能，从而成为独立的学术研究人员。在完成住院医师培训后，高素质的医生进入内科、儿科内分泌学或医学-儿科内分泌学联合奖学金，接受各自学科的临床培训[S]，然后在两个轨道中的一个进入这一综合计划，即内分泌学基础科学轨道或内分泌学临床研究轨道。这些课程提供广泛、直接和说教性质的研究培训。内分泌学基础科学课程需要一系列研究生水平的课程，包括分子生物学、生物统计学和研究伦理学的研究。内分泌学临床研究跟踪实习生通过我们的K30资助的Cite计划获得临床研究的理学硕士学位。内分泌科学家培训计划的受训人员将获得两年的培训支持。在之前的项目期间，该项目已经培训了五名内分泌学领域的顶尖内科科学家。该项目的毕业生都在主要医学院担任学术职位，我们预计他们将继续从事尖端研究，为美国人民的健康做出重大贡献。相关性(见说明)：2型糖尿病及相关内分泌和代谢问题的爆发正在对公众健康造成巨大损失。阐明疾病机制和开发针对这些疾病及相关疾病的新治疗方法是解决这些问题的关键。要做到这一点，只有培养一大批青年科研人员，发展和发扬解决这些问题的努力。

DESCRIPTION (provided by applicant): Disorders of endocrinology and metabolism are prevalent in the U.S. Addressing these difficult dilemmas requires not only the development of a critical mass of physicians to care for affected patients, but also the training of skilled researchers to develop innovative therapies and preventive measures and to delve into the basic mechanisms of diseases. The Indiana University School of Medicine is a leader in many fields of medicine. Its Section of Pediatric Endocrinology and the Division of Endocrinology and Metabolism in the Department of Medicine are both large well respected research divisions with long histories of mentoring pre-and postdoctoral trainees, including training one another's fellows in research that spans the spectrum of pediatric and adult Endocrinology. The Endocrine Scientist Training Program described here provides the opportunity for young scientists in Pediatric, Adult, or Combined Medicine-Pediatric Endocrinology training to enhance their skills in either basic laboratory, clinical, or translational research, leading to careers as independent academic researchers. After completion of their residency training, highly qualified physicians enter either the Internal Medicine, Pediatric Endocrinology, or combined Medicine- Pediatric Endocrinology fellowship, receive clinical training in the respective discipline[s), then enter this combined program in one of two tracks, the Basic Science of Endocrinology Track or the Endocrinology Clinical Research Track. These tracks provide extensive direct and didactic research training. The Basic Science of Endocrinology Track requires a series of graduate level courses, including studies in Molecular Biology, Biostatistics, and Research Ethics. The Endocrinology Clinical Research Track trainees obtain a Masters of Science in Clinical Research through our K30-funded CITE program. Trainees in the Endocrine Scientist Training Program receive two years of support for their training. Over the previous project period, this program has trained five top-notch physician scientists in the field of Endocrinology. The graduates of this program all have academic positions at major medical schools, and we anticipate that they will continu to engage in cutting-edge research to make major contributions to the health of the American people. RELEVANCE (See instructions): The eruption of type 2 diabetes and related endocrine and metabolic problems is taking a tremendous public health toll. The elucidation of disease mechanisms and the development of new treatments for these and related conditions is critical to address these issues. This can only be done by training a critical mass of young researchers to develop and carry forward the efforts to solve these problems.