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Modeling TH17 Cells in Acute GVHD

Modeling TH17 Cells in Acute GVHD
急性 GVHD 中 TH17 细胞的建模
批准号：
8124088
负责人：
Jonathan S. Serody
金额：
$37.2万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
项目状态：
已结题
起止时间：
2010-09-01 至 2011-08-31
来源：
https://reporter.nih.gov/project-details/8124088
关键词：
AbbreviationsAcuteAcute Graft Versus Host DiseaseAllogenicAnimal ModelAntibodiesAntigen-Presenting CellsAutoimmune DiseasesBiologyBiopsyBlocking AntibodiesCCR6 geneCD4 Positive T LymphocytesCell physiologyCellsCollagen ArthritisComplicationCutaneousDataDiseaseDisease modelEnvironmentEventExperimental Autoimmune EncephalomyelitisFunctional disorderGastrointestinal tract structureGenerationsGoalsHepaticImmuneIncidenceInflammatory Bowel DiseasesInfusion proceduresInterferonsInterleukin-12Interleukin-17Interleukin-2Interleukin-4LiverLungMajor Histocompatibility ComplexMediatingMediator of activation proteinMethodsMinorModelingMusOrganPathogenesisPathologyPathway interactionsPatientsPerceptionPhenotypePlayPopulationPreventionProcessProductionProteinsPsoriasisPublishingRecruitment ActivityRelative (related person)Research PersonnelRoleSTAT4 geneSTAT6 geneSeveritiesSeverity of illnessSignal TransductionSignaling ProteinSiteSkinSkin TransplantationSkin graftStem cell transplantT-Cell ActivationT-LymphocyteT-Lymphocyte SubsetsTNF geneTestingTh1 CellsTh2 CellsTissuesTransplantationTropismWorkYangautoreactivitychronic graft versus host diseaseclinically relevantcytokinegraft vs host diseaseinhibitor/antagonistinterleukin-22interleukin-23keratinocytemigrationneutrophilnovelnovel therapeutic interventionperforinpreventprogramspublic health relevancereceptorresearch studyskin disordertranscription factortumor

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期刊论文(1)
专著(0)
科研奖励(0)
会议论文
The IL-17 differentiation pathway and its role in transplant outcome.
DOI： 10.1016/j.bbmt.2011.10.001
发表时间： 2012-01
期刊： BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
影响因子： 4.3
作者： [Serody, Jonathan S., Hill, Geoffrey R.]
通讯作者： Hill, Geoffrey R.
UNC Immunotherapy Training Grant (IM-TAG)
SToP Cancer SPORE: Career Enhancement Program
SToP Cancer SPORE: Career Enhancement Program
Enhancing Innate Immune Reconstitution Post Allogeneic HSCT.
海外基金