Molecular Analyses of MG Pathogenesis in Human Cell Culture and Mouse Models

人类细胞培养和小鼠模型中 MG 发病机制的分子分析

• 批准号: 8132762
• 负责人: RICHARD B PYLES
• 金额: $ 38.25万
• 依托单位: UNIVERSITY OF TEXAS MED BR GALVESTON
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8132762
• 关键词: Acute; Address; Agonist; Air; Animal Model; Antibiotic Resistance; Apical; Bacterial Physiology; Cell Culture Techniques; Cells; Cervicitis; Chlamydia trachomatis; Clinical; Collaborations; Data; Development; Diagnostic; Disease; Epithelial Cells; Female; Fertility; Gene Expression; Gene Expression Profile; Genes; Genetic Transcription; Genital system; Genome; HIV; Human; Human Herpesvirus 2; Immune; Immune response; Immunosuppression; Infection; Infertility; Inflammatory; International; Intervention; Joints; Knockout Mice; Lead; Life Cycle Stages; Measures; Microbe; Modeling; Molecular; Molecular Analysis; Mycoplasma; Mycoplasma genitalium; Natural Immunity; Nature; Nonspecific urethritis; Open Reading Frames; Outcome; Pathogenesis; Pathology; Patients; Pattern; Pelvic Inflammatory Disease; Peripheral; Phenotype; Physiology; Predisposition; Prevalence; Process; Proteins; Proteome; Proteomics; Reporting; Reproductive Health; Research; Role; Set protein; Simplexvirus; Site; Stem cells; Testing; Tissues; Transcript; Urethritis; Vaccines; Vagina; Woman; axenic culture; cell type; cellular engineering; combat; extracellular; genital infection; insight; men; migration; mouse model; novel; numb protein; pathogen; public health relevance; reproductive; selective expression; tool; transmission process; vaccine development

项目成果

Transcriptional Analysis of the Guinea Pig Mucosal Immune Response to Intravaginal Infection with Herpes Simplex Virus Type 2.

• DOI: 10.1016/j.virol.2018.03.019
• 发表时间: 2018-05
• 期刊: Virology
• 影响因子: 3.7
• 作者: Veselenak RL;Milligan GN;Miller AL;Pyles RB;Bourne N
• 通讯作者: Bourne N