Regulation of PPARgamma in Adipocytes by Siah2

Siah2 对脂肪细胞中 PPARgamma 的调节

• 批准号: 8073701
• 负责人: ZELPHA ELIZABETH FLOYD
• 金额: $ 22.2万
• 依托单位: LSU PENNINGTON BIOMEDICAL RESEARCH CTR
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8073701
• 关键词: 2,4-thiazolidinedione; Adipocytes; Adipose tissue; Affect; Antidiabetic Drugs; Binding; Biological Models; Cardiovascular Diseases; Congestive Heart Failure; Data; Development; Diabetes Mellitus; Diet; Disease; Enzymes; Fracture; Glucose; Goals; Hypertension; Insulin; Insulin Resistance; Intervention; Ligand Binding; Link; Lipids; Metabolic syndrome; Modeling; Modification; Mus; Non-Insulin-Dependent Diabetes Mellitus; Nuclear Hormone Receptors; Nude Mice; Obesity; Obesity associated disease; PPAR Pathway; PPAR gamma; Pathway interactions; Peroxisome Proliferation; Pharmaceutical Preparations; Physiological; Play; Production; Proteins; Regulation; Risk; Risk Factors; Role; Screening procedure; Signal Pathway; Signal Transduction; Small Interfering RNA; System; Testing; Thiazolidinediones; Ubiquitin; Woman; adipocyte biology; base; blood glucose regulation; carbohydrate metabolism; cellular targeting; diabetic; glucose uptake; improved; in vivo; insight; insulin sensitivity; insulin signaling; interest; lipid biosynthesis; lipid metabolism; multicatalytic endopeptidase complex; new therapeutic target; novel; obesity treatment; polypeptide; protein degradation; protein expression; protein function; receptor; transcription factor; ubiquitin ligase; ubiquitin-protein ligase