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Pan-filovirus antivirals targeting the VP35 protein

Pan-filovirus antivirals targeting the VP35 protein
针对 VP35 蛋白的泛丝状病毒抗病毒药物
批准号：
8098345
负责人：
Christopher F Basler
金额：
$67.75万
依托单位：
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
项目状态：
已结题
起止时间：
2010-07-01 至 2011-06-30
来源：
https://reporter.nih.gov/project-details/8098345
关键词：
Amino AcidsAntiviral AgentsAntiviral ResponseBindingBinding ProteinsBiochemicalBiochemistryBiological AssayBioterrorismCategoriesCaviaCell Culture TechniquesCellsCellular biologyChemistryCollaborationsComplexComputer SimulationDataDemocratic Republic of the CongoDisease OutbreaksDouble-Stranded RNAElementsExhibitsFDA approvedFamilyFatal OutcomeFilovirusFrankfurt-Marburg Syndrome VirusGene ExpressionGoalsHealthHumanImmune responseImmunityIn VitroInfectionInterdisciplinary StudyInterferon-alphaInterferonsKnowledgeLaboratoriesLeadLinkMolecularNational Institute of Allergy and Infectious DiseaseNaturePathogenesisPathway interactionsPharmaceutical PreparationsPolymeraseProductionProphylactic treatmentProteinsRNA VirusesRecombinantsRoleSatellite VirusesSignal TransductionStructureTestingTherapeuticViralViral Hemorrhagic FeversVirulenceVirusVirus DiseasesVirus ReplicationWorkbasedrug discoveryin vivo Modelinhibitor/antagonistinsightmembermultidisciplinarymutantpathogenpreventresponsesmall moleculestructural biologyvirologyvirtual

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