SECONDARY SEXUAL CHARACTERISTICS IN BOYS SEEN IN OFFICE PRACTICE (SSCIB)

办公室实践中观察到的男孩的第二性特征 (SSCIB)

• 批准号: 8166629
• 负责人: Charlotte Todd
• 金额: $ 6.73万
• 依托单位: UNIVERSITY OF NEW MEXICO
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-12-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8166629
• 关键词: Age; Age of Onset; Appointment; Characteristics; Child; Childhood; Clinic; Clinical; Computer Retrieval of Information on Scientific Projects Database; Data; Eligibility Determination; Enrollment; Ethnic Origin; Funding; Future; Grant; Growth and Development function; Institution; Measurement; Pediatrics; Provider; Puberty; Publishing; Race; Research; Research Personnel; Resources; Sexual Development; Site; Source; Staging; Textbooks; United States National Institutes of Health; aged; base; boys; girls; male; population based; prospective; racial and ethnic; trend

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. A decade ago, research published in Pediatrics revealed that young girls were developing pubertal changes earlier than had been described in textbooks. Currently, preliminary data suggest that boys also may be starting to develop physically earlier than in the recent past but the validity of these findings is uncertain. The Secondary Sexual Characteristics in Boys (SSCIB) study will determine the stages of secondary sexual development and mean ages of onset of pubertal testicular enlargement among boys of varied racial and ethnic origin seen in pediatric practices in the U.S. today. Nearly, 7000 boys ages 6 through 16 years will be studied. This is a Prospective, Observational, Population-Based Study (based on participating providers). This study will aid in developing appropriate clinical standards by race/ethnicity for assessing typical growth and development in U.S. boys. This study will provide a basis for future studies by using Tanner Staging and Testicular Measurement (orchiometer) in early puberty, which will provide data for following secular trends. All males, aged 6 through 16 years who are seen in the UNM Pediatrics clinic for regular, well-child appointments with participating providers, will be screened for eligibility for enrollment. The projected number for UNM is 660 enrolled (Based on an estimated 22 participating providers at UNM, who each plan to enroll 30 subjects). The projected total number at multiple sites is 6600.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 十年前，《儿科》杂志上发表的研究表明，年轻女孩出现青春期变化的时间比教科书上描述的要早。目前，初步数据表明，男孩的身体发育也可能比最近更早，但这些发现的有效性尚不确定。男孩第二性特征 (SSCIB) 研究将确定当今美国儿科实践中不同种族和民族的男孩的第二性发育阶段和青春期睾丸增大的平均年龄。近 7000 名 6 至 16 岁的男孩将接受研究。这是一项基于人群的前瞻性、观察性研究（基于参与的提供者）。 这项研究将有助于按种族/民族制定适当的临床标准，以评估美国男孩的典型生长和发育。这项研究将为未来在青春期早期使用坦纳分期和睾丸测量（睾丸测量仪）的研究奠定基础，这将为后续的长期趋势提供数据。 所有在 UNM 儿科诊所与参与提供者定期进行儿童健康预约的 6 至 16 岁男性都将接受入学资格筛查。 UNM 的预计注册人数为 660 人（基于 UNM 估计的 22 家参与提供者，每家计划注册 30 名受试者）。预计多个地点的总人数为 6600 人。