Peru Infectious Diseases Epidemiology Research Training Consortium

描述（由申请人提供）：当前的流感大流行表明，在新发传染病的知识和应对能力方面存在明显差距。在我们的奖项“秘鲁传染病流行病学研究培训联盟”的第一阶段，国家传染病防治中心- upch - jhbsph - usuhs联盟为在秘鲁建立可持续的研究能力作出了贡献。两名硕士毕业生和一名博士候选人返回秘鲁，正在研究大流行性流感和季节性流感的主要流行病学和生态学方面，三名学员正在完成课程。此外，我们在秘鲁建立了一个几乎自给自足、学费资助的流行病学硕士项目，由30多名秘鲁/外国博士和博士候选人授课，其中许多人由NIH研究和培训资助。我们连续培训了两组43名学生，第一组的学生在培训的一年内在同行评审的期刊上发表了13篇论文。取得了重要进展，但仍需作出实质性努力。更新建议将通过以下方式巩固我们的工作：1)支持当前受训人员完成学位并培养他们返回秘鲁；2)在秘鲁完成建立一个世界级和自我可持续的流行病学硕士项目；3)通过流行病学暑期研究所扩大秘鲁的培训选择；4)通过4个专项硕士奖学金在安第斯卫生部建立能力；5)正式将疾病预防控制中心和圣马科斯大学纳入主要合作伙伴行列。该奖学金将资助2名博士研究生、20名硕士研究生和21名证书课程学生，其中30%在美国接受培训。该联盟将继续采用行之有效的、成功的方法，将课程作业、应用研究和指导成就驱动的进步结合起来，并利用所有可用的培训项目。受训者将准备一份方案，获得IRB批准，进行研究，提交手稿，申请外部资金，完成研究周期。培训将在联盟的良好环境中进行，包括许多成功的NIH合作，广泛的多年研究，大量训练有素的本地和外国导师，先进的实验室，以及不同的领域和临床站点。

DESCRIPTION (provided by applicant): The current influenza pandemic has made evident the gaps in knowledge about and response capacity for emerging infectious diseases. In the first stage of our award, "Peru Infectious Diseases Epidemiology Research Training Consortium", the NMRCD-UPCH-JHBSPH-USUHS consortium has contributed to building sustainable research capacity in Peru. Two Masters' graduates and one PhD candidate returned to Peru and are studying key epidemiologic and ecologic aspects of pandemic and seasonal influenza, and three trainees are finishing coursework. Also, we established a nearly self-sustainable, tuition-funded Epidemiology Masters in Peru which is taught by 30+ Peruvian/foreign PhDs and PhD candidates, many funded by NIH research and training grants. We have trained 43 students in two successive cohorts, and students from the first cohort have published 13 papers in peer-reviewed journals within a year of training. Important progress has been made, but substantial efforts are still needed. The renewal proposal will consolidate our work by 1) supporting degree completion of current trainees and nurturing return to Peru, and 2) complete establishment a world-class and self-sustainable Epidemiology Masters program in Peru, 3) broadening training options in Peru via a Summer Institute of Epidemiological Research, 4) build capacity in Andean Ministries of Health through 4 ear-marked Masters scholarships, 5) formally adding the CDC and Universidad San Marcos as key partners. This second award will support 2 PhD students, 20 Masters Graduates and 21 students of certificate programs, 30% of them trained in the US. The consortium will continue to use the proven, successful approach of combining coursework, applied research, and mentored achievement-driven progression and using all training programs available. Trainees will prepare a protocol, obtain IRB approval, conduct research, submit a manuscript, and apply for external funding, completing the research cycle. Training will take place in a superb environment of the consortium which includes numerous successful NIH collaborations, extensive multi-year research, a large pool of highly trained local and foreign mentors, sophisticated laboratories, and diverse field and clinical sites. Public Health Relevance: We built sustainable research capacity in our first award by creating a high-quality Epidemiology Masters Program in Peru and combining with advanced degree training in the US. The first trainees are conducting important studies on seasonal and pandemic influenza and published important studies rapidly. The renewal proposal should consolidate these efforts with further local training in Peru, reaching out to Ministries of Health in Andean countries and complete establishing self-sustainable advanced programs in Peru