Peru Infectious Diseases Epidemiology Research Training Consortium

描述（由申请人提供）：当前的流感大流行表明了对新发传染病的认识和应对能力方面的差距。在我们的“秘鲁传染病流行病学研究培训联合会”奖项的第一阶段，国家传染病研究和发展中心-UPCH-JHBSPH-USUHS联合会为建设秘鲁的可持续研究能力作出了贡献。两名硕士毕业生和一名博士候选人返回秘鲁，正在研究大流行病和季节性流感的关键流行病学和生态方面，三名受训人员正在完成课程。此外，我们在秘鲁建立了一个几乎自我维持的，学费资助的流行病学硕士学位，由30多名秘鲁/外国博士和博士候选人教授，其中许多人由NIH研究和培训赠款资助。我们已经连续两批培训了43名学生，第一批学生在培训的一年内在同行评议的期刊上发表了13篇论文。已经取得重要进展，但仍需作出重大努力。更新提案将通过以下方式巩固我们的工作：1）支持现有学员完成学位并培养返回秘鲁的人才，2）在秘鲁完成世界一流的自我可持续的流行病学硕士课程，3）通过流行病学研究暑期学院扩大秘鲁的培训选择，4）通过4个专项硕士奖学金在安第斯卫生部建立能力，5）正式加入CDC和圣马科斯大学作为主要合作伙伴。第二个奖项将支持2名博士生，20名硕士毕业生和21名证书课程的学生，其中30%在美国接受培训。该联盟将继续使用经过验证的成功方法，将课程作业，应用研究和指导性的成就驱动的进展相结合，并使用所有可用的培训课程。受训者将准备一份方案，获得IRB批准，进行研究，提交手稿，并申请外部资金，完成研究周期。培训将在该联盟的一流环境中进行，其中包括许多成功的NIH合作，广泛的多年研究，大量训练有素的本地和外国导师，先进的实验室以及多样化的现场和临床站点。 公共卫生相关性：我们通过在秘鲁创建高质量的流行病学硕士课程并结合美国的高级学位培训，在我们的第一个奖项中建立了可持续的研究能力。第一批受训人员正在进行关于季节性流感和大流行性流感的重要研究，并迅速发表了重要研究报告。更新提案应通过在秘鲁进一步开展当地培训、与安第斯国家卫生部联系并在秘鲁完成建立自我维持的高级方案来巩固这些努力

DESCRIPTION (provided by applicant): The current influenza pandemic has made evident the gaps in knowledge about and response capacity for emerging infectious diseases. In the first stage of our award, "Peru Infectious Diseases Epidemiology Research Training Consortium", the NMRCD-UPCH-JHBSPH-USUHS consortium has contributed to building sustainable research capacity in Peru. Two Masters' graduates and one PhD candidate returned to Peru and are studying key epidemiologic and ecologic aspects of pandemic and seasonal influenza, and three trainees are finishing coursework. Also, we established a nearly self-sustainable, tuition-funded Epidemiology Masters in Peru which is taught by 30+ Peruvian/foreign PhDs and PhD candidates, many funded by NIH research and training grants. We have trained 43 students in two successive cohorts, and students from the first cohort have published 13 papers in peer-reviewed journals within a year of training. Important progress has been made, but substantial efforts are still needed. The renewal proposal will consolidate our work by 1) supporting degree completion of current trainees and nurturing return to Peru, and 2) complete establishment a world-class and self-sustainable Epidemiology Masters program in Peru, 3) broadening training options in Peru via a Summer Institute of Epidemiological Research, 4) build capacity in Andean Ministries of Health through 4 ear-marked Masters scholarships, 5) formally adding the CDC and Universidad San Marcos as key partners. This second award will support 2 PhD students, 20 Masters Graduates and 21 students of certificate programs, 30% of them trained in the US. The consortium will continue to use the proven, successful approach of combining coursework, applied research, and mentored achievement-driven progression and using all training programs available. Trainees will prepare a protocol, obtain IRB approval, conduct research, submit a manuscript, and apply for external funding, completing the research cycle. Training will take place in a superb environment of the consortium which includes numerous successful NIH collaborations, extensive multi-year research, a large pool of highly trained local and foreign mentors, sophisticated laboratories, and diverse field and clinical sites. Public Health Relevance: We built sustainable research capacity in our first award by creating a high-quality Epidemiology Masters Program in Peru and combining with advanced degree training in the US. The first trainees are conducting important studies on seasonal and pandemic influenza and published important studies rapidly. The renewal proposal should consolidate these efforts with further local training in Peru, reaching out to Ministries of Health in Andean countries and complete establishing self-sustainable advanced programs in Peru