Center on the Microenvironment and Metastasis

微环境和转移中心

• 批准号: 7942785
• 负责人: MICHAEL L SHULER
• 金额: $ 257.21万
• 依托单位: CORNELL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-28 至 2014-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7942785
• 关键词: 3-Dimensional; Advisory Committees; Animal Experiments; Animal Model; Animals; Area; Biomedical Engineering; Blood Vessels; Buffaloes; Cancer Biology; Cancer Model; Cancerous; Cell Count; Cells; Characteristics; Chemicals; Collaborations; Committee Members; Complex; Cues; Development; Disease; Distant; Drug Delivery Systems; Education; Engineering; Environment; Environmental Exposure; Faculty; Future; Growth; Growth Factor; Heterogeneity; Human; Immunocompromised Host; In Vitro; Individual; Institution; Interdisciplinary Study; Knowledge; Laboratories; Lead; Link; Location; Malignant Neoplasms; Measurement; Mechanics; Methods; Microfabrication; Morbidity - disease rate; Mutation; Nanotechnology; Nature; Neoplasm Metastasis; New York; New York City; Normal Cell; Nutrient; Oncogenic; Patients; Physics; Physiological; Play; Procedures; Process; Property; Recommendation; Reporting; Research; Research Personnel; Research Project Grants; Resource Sharing; Role; Scientist; Signal Transduction; Site; Stimulus; Stromal Cells; Structure; Supporting Cell; System; Techniques; Technology; Time; Tissue Model; Tissues; Universities; anticancer research; cancer cell; cancer stem cell; cell growth; experience; human tissue; insight; mathematical model; medical schools; meetings; member; mortality; nano; nanobiotechnology; neoplastic cell; novel; oncology; physical science; research facility; research study; response; success; tumor; tumor growth; tumor progression

DESCRIPTION (provided by applicant): The Center on the Microenvironment and Metastasis will be operated as a Multi-Institutional Interdisciplinary Research Center managed by Cornell University using established mechanisms and an experienced financial, administration and technical support staff. Our PS-OC organization will incorporate successful process management procedures developed at Cornell. Existing administrative structures and resources, shared research facilities and underlying technological capabilities will be utilized for this new PS-OC enterprise targeted toward cancer research, Cornell University will be the lead institution of our Center on the Microenvironment and Metastasis. The university has a strong tradition of multi-institutional research organizations and PS-OC faculty and staff will build on this to establish a PS-OC organization that will quickly and effectively support and enhance the research projects of the Center. Our Center will include leaders in the fields of physics, nanobiotechnology, nanotechnology and biomedical engineering at Cornell. Leaders in cancer biology research from V\/eill Cornell Medical College in New York City will play a critical role in our Center, as will colleagues at the State University of New York at Buffalo. The Center Advisory Committee will assess overall progress in research, education, and implementation, and partnership development. This assessment will be set in the context of each committee member's area of expertise, as these members collectively will represent the core areas of the center. Key recommendations for future development of the Center will be decided upon by this group, and reports from their meetings will be shared with the Center Director and the Executive Committee We recognize the important role the Physical Sciences-Oncology Centers Steering Committee (PSC) will play in the success of the PS-OC network. Our Center will be represented on this committee by Harold Craighead (Pi/Director) and Barbara Hempstead (senior co-investigator/Co-Director). Our PS-OC representatives on this committee will bring detailed knowledge of progress in our Center's research projects that will enable them to propose and promote collaborations with colleagues at other PS-OCs through trans-Network projects.

描述（由申请人提供）：微环境和转移中心将作为一个多机构跨学科研究中心，由康奈尔大学管理，使用既定的机制和经验丰富的财务，行政和技术支持人员。我们的PS-OC组织将采用康奈尔大学开发的成功流程管理程序。现有的行政结构和资源，共享的研究设施和基础技术能力将用于这个新的PS-OC企业，目标是癌症研究，康奈尔大学将成为我们的微环境和转移中心的领导机构。该大学拥有多机构研究组织的悠久传统，PS-OC的教职员工将在此基础上建立一个PS-OC组织，以快速有效地支持和加强该中心的研究项目。我们的中心将包括物理学，纳米生物技术，纳米技术和生物医学工程领域的领导者在康奈尔大学。来自纽约市V/eill Cornell医学院的癌症生物学研究领导者将在我们中心发挥关键作用，布法罗的纽约州立大学的同事也将发挥关键作用。中心咨询委员会将评估研究、教育和实施以及伙伴关系发展的总体进展。这项评估将根据每个委员会成员的专业领域进行，因为这些成员共同代表中心的核心领域。该小组将决定该中心未来发展的关键建议，会议报告将与中心主任和执行委员会分享。我们认识到物理科学-肿瘤中心指导委员会（PSC）将在PS-OC网络的成功中发挥重要作用。我们中心将由Harold Craighead（PI/主任）和Barbara Hempstead（高级共同研究员/共同主任）代表参加该委员会。我们的PS-OC在这个委员会的代表将带来我们中心的研究项目的进展的详细知识，这将使他们能够通过跨网络项目提出和促进与其他PS-OC的同事合作。