Center on the Microenvironment and Metastasis

描述（申请人提供）：微环境和转移中心将作为一个多机构跨学科的研究中心，由康奈尔大学管理，拥有成熟的机制和经验丰富的财务、行政和技术支持人员。我们的PS-OC组织将整合康奈尔大学开发的成功流程管理程序。现有的管理结构和资源、共享的研究设施和潜在的技术能力将被用于这个新的针对癌症研究的PS-OC企业，康奈尔大学将成为我们的微环境和转移中心的领导机构。该校拥有多机构研究组织的强大传统，PS-OC的教职员工将以此为基础建立PS-OC组织，以快速有效地支持和加强中心的研究项目。我们的中心将包括康奈尔大学物理学、纳米生物技术、纳米技术和生物医学工程领域的领导者。来自纽约市康奈尔医学院的癌症生物学研究的领导者将在我们的中心发挥关键作用，纽约州立大学布法罗分校的同事也将发挥重要作用。中心咨询委员会将评估研究、教育、实施和伙伴关系发展方面的总体进展。评估将根据每个委员会成员的专业领域进行，因为这些成员将共同代表中心的核心领域。该小组将决定中心未来发展的关键建议，其会议报告将与中心主任和执行委员会共享。我们认识到物理科学-肿瘤中心指导委员会（PSC）将在PS-OC网络的成功中发挥重要作用。本中心将由Harold Craighead （Pi/主任）和Barbara Hempstead（高级联合研究员/联合主任）代表参加委员会。本委员会的PS-OC代表将带来本中心研究项目进展的详细知识，使他们能够通过跨网络项目提出并促进与其他PS-OC同事的合作。

DESCRIPTION (provided by applicant): The Center on the Microenvironment and Metastasis will be operated as a Multi-Institutional Interdisciplinary Research Center managed by Cornell University using established mechanisms and an experienced financial, administration and technical support staff. Our PS-OC organization will incorporate successful process management procedures developed at Cornell. Existing administrative structures and resources, shared research facilities and underlying technological capabilities will be utilized for this new PS-OC enterprise targeted toward cancer research, Cornell University will be the lead institution of our Center on the Microenvironment and Metastasis. The university has a strong tradition of multi-institutional research organizations and PS-OC faculty and staff will build on this to establish a PS-OC organization that will quickly and effectively support and enhance the research projects of the Center. Our Center will include leaders in the fields of physics, nanobiotechnology, nanotechnology and biomedical engineering at Cornell. Leaders in cancer biology research from V\/eill Cornell Medical College in New York City will play a critical role in our Center, as will colleagues at the State University of New York at Buffalo. The Center Advisory Committee will assess overall progress in research, education, and implementation, and partnership development. This assessment will be set in the context of each committee member's area of expertise, as these members collectively will represent the core areas of the center. Key recommendations for future development of the Center will be decided upon by this group, and reports from their meetings will be shared with the Center Director and the Executive Committee We recognize the important role the Physical Sciences-Oncology Centers Steering Committee (PSC) will play in the success of the PS-OC network. Our Center will be represented on this committee by Harold Craighead (Pi/Director) and Barbara Hempstead (senior co-investigator/Co-Director). Our PS-OC representatives on this committee will bring detailed knowledge of progress in our Center's research projects that will enable them to propose and promote collaborations with colleagues at other PS-OCs through trans-Network projects.