Core G: Patient-Oriented Research Core

以患者为导向的研究核心（PORC）继续按照最初的设想发挥作用， 大规模合作项目，包括临床、生理、病理生理和结局数据以及样本 支持对许多表型、蛋白质组学和基因组改变的分析和解释， 在严重创伤诱导的先天免疫反应，特别是炎症反应的患者中的相互作用。 核心人员从严重受伤的病人身上识别、招募、输入和获取样本（血液和组织）， 器官功能障碍/衰竭、感染性并发症和死亡率的风险。临床研究者从 PORC还与信息传播和数据协调、临床生物统计学和 数据解释核心，以帮助使生物和临床意义的数据。

The Patient-Oriented Research Core (PORC) continues to function as originally envisioned to provide the large-scale collaborative project with clinical, physiologic, pathophysiologic, and outcomes data, and samples to support the analyses and interpretation of the numerous phenotypic, proteomic, and genomic alterations and interactions in patients with severe trauma-induced innate immune and particularly inflammatory responses. The Core identifies, recruits, enters, and obtains samples (blood and tissue) from severely injured patients at risk for organ dysfunction/failure, infectious complications, and mortality. The clinical investigators from the PORC also work closely with the Information Dissemination and Data Coordination, Clinical Biostatistics, and Data Interpretation Cores to help make biological and clinical sense of the data.