High-throughput desk-top FT-ICR instrument; Phase II SBIR application for the 1R4
High-throughput desk-top FT-ICR instrument; Phase II SBIR application for the 1R4
批准号:
8136465
负责人:
ALEXANDER MISHARIN
金额:
$37.5万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2008
资助国家:
美国
项目状态:
已结题
起止时间:
2008-07-01 至 2013-06-30
关键词:
AppearanceBiological SciencesCellsCharacteristicsChargeChromatographyComplex MixturesCyclotronsDataDetectionDevicesDissociationElectrodesElectronsElectrospray IonizationEngineeringEvaluationFourier TransformFrequenciesFutureGoalsGovernmentGrantHandHeightHigh Pressure Liquid ChromatographyHybridsInformation SciencesIonsLeftLegalLibrariesManufacturer NameMarketingMass Spectrum AnalysisMeasurementMethodsMotionPeptidesPerformancePersonsPhasePost Translational Modification AnalysisPriceProgress ReportsProteinsProteomicsResearchResolutionSHFM1 geneScanningSchemeScreening procedureServicesSmall Business Innovation Research GrantSpeedSystemTechniquesTechnologyTimeWorkbaseclinical applicationcombinatorialdrug discoveryhigh throughput technologyimprovedinstrumentinstrumentationmass spectrometernoveloperationprotein aminoacid sequencepublic health relevanceresearch studysmall moleculetandem mass spectrometrytime useultra high resolution
中文摘要
描述(由申请人提供):我们建议开发一种新型台式FT-ICR质谱仪,采用O-trap FT-ICR池技术,用于蛋白质组学研究和小分子应用的高通量、超高性能MS和多种类型(CID、ECD、HECD和EDD)MS/MS分析(每秒4 - 10个光谱,R = 100,000 - 25,000,m/z 400)。
公共卫生相关性:我们提出了一种新型的高通量5 T台式FT-ICR仪器。
英文摘要
DESCRIPTION (provided by applicant): We propose to develop a novel desk-top FT-ICR mass spectrometer with O-trap FT-ICR cell technology for high throughput, ultra-high performance MS and multy-type (CID, ECD, HECD, and EDD) MS/MS analysis (4 - 10 spectra per second with R = 100,000 - 25,000 at m/z 400) for proteomics research and small molecule applications.
PUBLIC HEALTH RELEVANCE: We propose a novel high-throughput 5T desk-top FT-ICR instrument.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Broadband ultrasensitive detector for FTICR mass spectrometers
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批准号:8253082
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项目类别:
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资助金额:$16.69万
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财政年份:2012
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负责人:ALEXANDER MISHARIN
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依托单位:
High-throughput desk-top FT-ICR instrument; Phase II SBIR application for the 1R4
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批准号:7910204
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项目类别:
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资助金额:$37.5万
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财政年份:2008
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负责人:ALEXANDER MISHARIN
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依托单位:
海外基金