Administrative, Biostatistics and Enrichment Core

超过1/3的美国成年人和17%的儿童肥胖。国家卫生研究院高度重视 旨在预防和治疗肥胖并打破肥胖及其相关疾病之间的联系 健康状况。中大西洋营养和肥胖研究中心（NORC）的使命，现在在其 第九年，是促进多学科研究方法，以了解营养和肥胖的影响 并将这些知识转化为有效的临床治疗和预防工作。 为了执行这一使命，中大西洋NORC包括一个充满活力的营养和肥胖社区 三个不同机构的研究人员。NORC由四个核心和两个程序组成， 彼此密切互动，无缝提供广泛的跨学科成本效益服务 中大西洋NORC调查人员的资源。 行政、生物统计和浓缩核心有几项职能。首先是 ABE核心负责全面领导，管理，监督和协调多个 NORC的活动。具体而言，ABE核心促进研究人员之间的协作与合作 在三个上级机构：马里兰州医学院，约翰霍普金斯大学 医学院和盖辛格卫生系统。此外，ABE核心促进合作 生物医学研究的三大核心：（1）生物机制与功能基因组学;（2） 分子遗传学和营养基因组学;（3）临床和转化研究。ABE核心也是 负责监督两个重要计划：（1）试点和可行性赠款计划，提供 小额研究补助金主要提供给早期研究人员，以促进他们在以下领域的职业发展： 营养和肥胖研究;（2）促进与以下方面有关的继续教育的丰富计划： 营养和肥胖，以保持NORC研究人员在该领域的知识前沿。最后， ABE核心包含与NORC合作的生物统计学和医学信息学子核心 研究人员确保以科学严谨的方式分析数据。总的来说，NORC 促进和实现跨基因组学，分子和细胞生物学，动物模型， 生物统计学和计算生物学，生理学，临床和转化研究，流行病学和 人口科学，以推进个性化的遗传和生活方式干预计划。

Over 1/3 of adult Americans and 17% of children are obese. The NIH has assigned high priority to research aimed at preventing and treating obesity and toward breaking the link between obesity and its associated health conditions. The mission of the Mid-Atlantic Nutrition and Obesity Research Center (NORC), now in its ninth year, is to foster multidisciplinary research approaches to understand the impact of nutrition and obesity on risk for chronic disease and translate this knowledge into effective clinical treatments and prevention efforts. Carrying out this mission, the Mid-Atlantic NORC includes a vibrant community of nutrition and obesity researchers across three different institutions. The NORC consists of four Cores and two Programs that interact closely with each other to seamlessly provide a wide range of interdisciplinary cost-effective services and resources to Mid-Atlantic NORC investigators. The Administrative, Biostatistics and Enrichment (ABE) Core has several functions. First and foremost, the ABE Core is responsible for overall leadership, administration, oversight, and coordination of the multiple activities in the NORC. Specifically, the ABE Core promotes collaboration and cooperation among researchers at the three parent institutions: University of Maryland School of Medicine, The Johns Hopkins University School of Medicine, and the Geisinger Health System. Furthermore, the ABE Core promotes collaboration among the three Biomedical Research Cores: (1) Biological Mechanisms and Functional Genomics; (2) Molecular Genetics and Nutrigenomics; and (3) Clinical and Translational Research. The ABE Core is also responsible for oversight of two important programs: (1) The Pilot and Feasibility Grant program that provides small research grants primarily to early stage investigators to promote their career development in the field of nutrition and obesity research; and (2) the Enrichment program that promotes continuing education related to nutrition and obesity in order to keep NORC researchers at the cutting edge of knowledge in the field. Finally, the ABE Core contains the Biostatistics and Medical Informatics Sub-Core that partners with NORC researchers to ensure that data is analyzed in a scientifically rigorous fashion. Collectively, the NORC promotes and enables multi-disciplinary research across genomics, molecular and cell biology, animal models, biostatistics and computation biology, physiology, clinical and translational research, and epidemiology and population science to advance a program of personalized genetic and lifestyle interventions.