Clinical evaluation and development of a diagnostic multi-modal intravascular imaging system
Clinical evaluation and development of a diagnostic multi-modal intravascular imaging system
批准号:
8976336
负责人:
Tirunelveli Ramalingam
金额:
$35.04万
依托单位国家:
美国
项目类别:
财政年份:
2015
资助国家:
美国
项目状态:
已结题
起止时间:
2015-09-01 至 2016-06-30
关键词:
AddressAffectAngiographyAreaArterial Fatty StreakArteriesBackBiopsyBlood VesselsBostonCadaverCaliberCaliforniaCardiovascular DiseasesCathetersClinicalClinical ResearchClinical TrialsComputer softwareContrast MediaCoronaryCouplingDataDecision MakingDetectionDevelopmentDiagnosisDiagnosticDimensionsDisease OutcomeDocumentationEarly DiagnosisElementsEnsureExposure toFDA approvedFamily suidaeFundingHeartHeart DiseasesHistopathologyHospital CostsHospitalsHumanHybridsImageImageryImaging TechniquesInstitutionLaboratoriesLeadLengthLettersLicensingMarketingMeasurementMeasuresMedicalMedical DeviceMedical ImagingModalityModelingMulti-Institutional Clinical TrialMultimodal ImagingOptical Coherence TomographyOutcomePatientsPennsylvaniaPhaseProceduresResearch PersonnelResolutionRotationSafetySaint Jude Children&aposs Research HospitalSalesSamplingSensitivity and SpecificitySiteSpecialistSpeedStenosisStentsSystemSystems DevelopmentTechnologyTestingThrombusTimeTissuesTorqueTranslationsUltrasonographyUniversitiesWorkabstractingbasebiomaterial compatibilitycostcost effectivefollow-upimaging systemimplantationimprovedmedical schoolsmillimeterminiaturizemortalitynoveloutcome forecastperformance testspreventprospectivepublic health relevanceresearch clinical testingsafety testingsensorstent thrombosissuccesstime useultra high resolutionvolcano
中文摘要
英文摘要
DESCRIPTION (provided by applicant): Understanding that not a single imaging technique can alone address needs of all vascular diagnosis, OCT medical imaging Inc. (OCTMI) propose to develop a clinical multimodal intravascular imaging system encompassing ultra-high resolution optical coherence tomography(OCT) and IVUS. This Combined multimodal vascular imaging system will permit cross-sectional visualization of vascular artery with unprecedented resolution and depth not possible with any of these technologies alone. This multi-modal imaging strategy in a single system permits use of a single disposable guide wire, thereby reducing cost to hospital, patients and improving prognosis by early detection. We believe these technologies together will provide 1) critical 3D and cross-sectional details & functional information necessary for identifying vulnerable plaques 2) inside-out view of vessel necessary for stent sizing 3) extent of mal-apposition of stent struts in artery 4) extent of post-stent thrombosis. In a multi-institutional effort, we plan to create this multi-modal probe and necessary
hardware in Phase I, followed by extensive clinical trials in phase II before seeking FDA approval and marketing in Phase III
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Office based real-time high speed 3D-OCT system for diagnosis of early laryngeal
-
批准号:8525019
-
项目类别:
-
资助金额:$92.85万
-
财政年份:2013
-
负责人:Tirunelveli Ramalingam
-
依托单位:
Office based real-time high speed 3D-OCT system for diagnosis of early laryngeal
-
批准号:8692703
-
项目类别:
-
资助金额:$99.35万
-
财政年份:2013
-
负责人:Tirunelveli Ramalingam
-
依托单位:
3D Real-time imaging system for Subglottic Stenosis and Edema in Neonates
-
批准号:8253516
-
项目类别:
-
资助金额:$32.3万
-
财政年份:2012
-
负责人:Tirunelveli Ramalingam
-
依托单位:
3D Real-time imaging system for Subglottic Stenosis and Edema in Neonates
-
批准号:8441591
-
项目类别:
-
资助金额:$30.85万
-
财政年份:2012
-
负责人:Tirunelveli Ramalingam
-
依托单位:
Office based Real-time high Speed 3-D OCT system for Diagnosis of EarlyLaryngeal
-
批准号:7804402
-
项目类别:
-
资助金额:$34.62万
-
财政年份:2010
-
负责人:Tirunelveli Ramalingam
-
依托单位:
Office based Real-time high Speed 3-D OCT system for Diagnosis of EarlyLaryngeal
-
批准号:8053291
-
项目类别:
-
资助金额:$34.7万
-
财政年份:2010
-
负责人:Tirunelveli Ramalingam
-
依托单位:
海外基金