ADDRESSING TB CONTROL AND LUNG HEALTH ACTIVITIES THROUGH THE VIETNAM NATIONAL LUN

通过越南国家 LUN 开展结核病控制和肺部健康活动

• 批准号: 8233778
• 负责人: SY DINH
• 金额: $ 19.98万
• 依托单位: VIETNAM NATIONAL LUNG HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-30 至 2016-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8233778
• 关键词: ADDRESSING; TB; CONTROL; LUNG; HEALTH

DESCRIPTION (provided by applicant): Tuberculosis (TB) is a leading cause of death among persons living with HIV (PLHIV), and screening for TB in all PLHIV is recommended. An evidence-based approach to TB screening and diagnosis was identified through the three-country "ID-TB/HIV study" conducted in Vietnam, Thailand and Cambodia. The TB screening algorithm derived from the ID-TB/HIV study is now being implemented and evaluated in two cities in Vietnam as a programmatic implementation and evaluation of one-time screening, determined to be non-research by CDC. An outstanding question not addressed by the ID-TB/HIV study is the yield of using the ID-TB/HIV algorithm when used repeatedly over time to screen for TB among PLHIV. This study will assess that question by applying the algorithm repeatedly over time for consenting participants who have had baseline screening as part of the programmatic evaluation.

描述（由申请人提供）：结核病（TB）是艾滋病毒感染者（PLHIV）死亡的主要原因，建议对所有PLHIV进行结核病筛查。通过在越南、泰国和柬埔寨进行的三国“ID-TB/HIV研究”，确定了以证据为基础的结核病筛查和诊断方法。目前正在越南的两个城市实施和评估ID-TB/HIV研究得出的结核病筛查算法，作为一次性筛查的方案实施和评估，CDC确定其为非研究。ID-TB/HIV研究没有解决的一个突出问题是，随着时间的推移，反复使用ID-TB/HIV算法来筛查艾滋病毒感染者中的结核病时，其收益率如何。本研究将通过对已接受基线筛选（作为项目评价的一部分）的知情受试者随时间重复应用该算法来评估该问题。