Molecular Mechanisms of Histoplasma Pathogenesis

组织胞浆菌发病机制的分子机制

• 批准号: 8297410
• 负责人: WILLIAM E GOLDMAN
• 金额: $ 37万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-15 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8297410
• 关键词: Adherence; Affect; Amylases; Antifungal Agents; Antigen Presentation Pathway; Attention; Bacterial Adhesins; Binding Proteins; Bioinformatics; Biological Models; Biology; Blastomyces dermatitidis; Cell Wall; Cells; Characteristics; Climate; Complement Factor H; Data; Defect; Development; Disease; Drug Delivery Systems; Family; Funding; Gene Expression; Gene Family; Gene Proteins; Genes; Geographic Distribution; Glucans; Goals; Grant; Haploidy; Histoplasma; Histoplasma capsulatum; Histoplasmosis; Human; Human Pathology; Immune; Immune response; Immunocompromised Host; Infection; Link; Lipid Binding; Lung; Mammalian Cell; Mammals; Masks; Membrane; Molds; Molecular; Molecular Genetics; Mus; Mutagenesis; Nutrient; Organism; Pathogenesis; Penicillium; Phagosomes; Phase; Phospholipase; Polysaccharides; Process; Production; Proliferating; Proteins; Regulation; Research; Resolution; Respiratory Tract Infections; Role; Saposins; Soil; Sphingolipid Activator Protein-1; Sporothrix; Structure; Study models; Systemic disease; Temperature; Testing; Transcriptional Regulation; Virulence; Virulence Factors; Work; Yeasts; Zoonoses; dectin 1; design; fungus; glucan synthase; inhibitor/antagonist; intracellular parasitism; macrophage; member; mutant; novel; pathogen; research study; three dimensional structure; tool