Connexin Distribution in Physiological Versus Pathological Cardiac Hypertrophy

生理性与病理性心脏肥大中的连接蛋白分布

• 批准号: 7903963
• 负责人: GEORGE COOPER
• 金额: --
• 依托单位: RALPH H JOHNSON VA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-10-01 至 2013-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7903963
• 关键词: Accounting; Address; Adenoviruses; Adrenergic Agents; Adrenergic Agonists; Adrenergic Receptor; Adult; Affinity; Agonist; Aliquot; Animal Model; Animals; Applications Grants; Arrestins; Arrhythmia; Atrial Heart Septal Defects; Attenuated; Basic Science; Binding; Biopsy; Cadherins; Canis familiaris; Cardiac; Cardiac Myocytes; Caring; Catheterization; Cell Adhesion; Cell Nucleolus; Cell Nucleus; Cell surface; Cells; Characteristics; Chronic; Clinical; Complex; Confocal Microscopy; Congenital Heart Defects; Connexin 43; Connexins; Connexon; Control Animal; Cyclic AMP; Cytoplasm; Cytoskeleton; Data; Dependence; Diffuse; Diffusion; Distal; Docking; Down-Regulation; Dynein ATPase; Echocardiography; Electrocardiogram; Electrons; Elements; Environment; Event; Exhibits; Failure; Family; Family Felidae; Felis catus; Functional disorder; Funding; Gap Junctions; Genes; Genetic Transcription; Genetic screening method; Goals; Golgi Apparatus; Grant; Grant Review; Growth; Heart; Heart Diseases; Heart Hypertrophy; Heart failure; Homeostasis; Human; Hypertrophy; Immunoblotting; Infection; Interphase Cell; Intervention; Intracellular Transport; Kinesin; Lead; Left; Left ventricular structure; Life; Life Cycle Stages; Location; Lung; Lysosomes; MAP4; Maps; Measurement; Measures; Mechanics; Mediating; Medical center; Membrane; Membrane Transport Proteins; Messenger RNA; Metalcaptase; Methods; Microfilaments; Microtubule Depolymerization; Microtubule Proteins; Microtubule-Associated Proteins; Microtubules; Minor; Modeling; Molecular; Morphology; Motion; Motor; Mus; Myocardial; Myocardium; Myofibrils; Nocodazole; Normal Cell; Normal Range; Optics; Pathway interactions; Patients; Pharmaceutical Preparations; Phase; Phenotype; Phosphoric Monoester Hydrolases; Phosphotransferases; Physiological; Plus End of the Microtubule; Positioning Attribute; Prevention; Principal Investigator; Process; Program Reviews; Progress Reports; Property; Propranolol; Protein Biosynthesis; Protein Dephosphorylation; Protein Isoforms; Protein phosphatase; Proteins; Protocols documentation; Pulmonary artery structure; Recruitment Activity; Research; Research Support; Ribonucleoproteins; Ribosomal RNA; Ribosomes; Right ventricular structure; Right-On; Role; Sarcolemma; Science; Series; Site; Specificity; Staining method; Stains; Stimulus; Stress; Structure; System; Systolic Pressure; Telemetry; Testing; Therapeutic Intervention; Thinking; Time; Tissues; Transfection; Transgenic Mice; Translating; Translational Research; Translations; Transport Process; Transport Vesicles; Treatment Efficacy; Tubulin; Up-Regulation; Ventricular; Vesicle; Work; adrenergic; base; beta-adrenergic receptor; constriction; density; extracellular; gap junction channel; gene therapy; hemodynamics; improved; interest; macromolecule; member; messenger ribonucleoprotein; overexpression; p21-activated kinase 1; palliative; particle; pressure; prevent; programs; public health relevance; receptor; receptor internalization; receptor recycling; research study; response; small molecule; success; trans-Golgi Network