Regulation of Migration of Autoreactive Germinal Centers and Precursor B Cells
Regulation of Migration of Autoreactive Germinal Centers and Precursor B Cells
批准号:
7904905
负责人:
John D Mountz
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-10-01 至 2013-09-30
关键词:
AddressAffinityAntigen PresentationAntigensAreaAutoantibodiesAutoantigensAutoimmune DiseasesAutoimmune ProcessAutoimmunityB-Lymphocyte SubsetsB-LymphocytesBehaviorCD4 Positive T LymphocytesCXCL12 geneCXCL13 geneCell MaturationCell physiologyCellsChemotaxisCollectionComplement 3d ReceptorsConfocal MicroscopyDataDendritic CellsDevelopmentEventExhibitsGTP-Binding Protein RegulatorsGenerationsGoalsHomingHumanImmunoglobulin MIn VitroInterferon-alphaInterferonsInterleukin-17LettersLupusLymphocyteMaintenanceMediatingMediator of activation proteinModelingMusNational Institute of Allergy and Infectious DiseasePatientsPhenotypePlayPopulationPreventionProductionPublicationsRGS Family GeneRegulationResearch PersonnelRheumatoid ArthritisRoleSamplingSeriesSignal TransductionSinusSpleenStructure of germinal center of lymph nodeSystemic Lupus ErythematosusT-Cell ProliferationTNFRSF5 geneTechniquesTestingTherapeutic InterventionTimeTransportationUp-Regulationabstractingclinically relevantin vivomigrationmodel developmentmouse modelnovelnovel therapeutic interventionperipheral bloodpublic health relevanceresponsetherapeutic target
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