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Toll-like receptor signaling in pathogenesis of pulmonary hypertension

Toll-like receptor signaling in pathogenesis of pulmonary hypertension
肺动脉高压发病机制中的Toll样受体信号传导
批准号：
7782773
负责人：
Yabing Chen
金额：
$0.0万
依托单位：
BIRMINGHAM VA MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
项目状态：
已结题
起止时间：
2009-04-01 至 2013-09-30
来源：
https://reporter.nih.gov/project-details/7782773
关键词：
Adaptor Signaling ProteinAffectAgeAttentionC3H/HeJ MouseCell ProliferationChronicChronic lung diseaseDevelopmentDiseaseEndothelial CellsExhibitsFamilyFigs - dietaryGenotypeHealthHeart DiseasesHypoxiaImmuneImmunityIn VitroInterleukin-1 ReceptorsInvestigationKnowledgeLeadLifeLungLung diseasesMediatingMediator of activation proteinMolecularMorbidity - disease rateMusMutationMyelogenousNADPH OxidaseNatural ImmunityOxidantsOxidation-ReductionOxidative StressPathogenesisPathway interactionsPatientsPattern RecognitionPlayPopulationPreventionProductionPulmonary EmphysemaPulmonary HypertensionPulmonary artery structureQuality of lifeReactive Oxygen SpeciesReceptor SignalingRegulationReportingRight ventricular structureRoleSignal PathwaySignal TransductionSmooth Muscle MyocytesStructureTLR2 geneTestingToll-like receptorsVascular remodelingVeteransbaseimprovedin vivolung injurymembermicrobialmortalitymouse toll-like receptor 4mutant mouse modelnovelnovel strategiesnovel therapeuticspreventpublic health relevancepulmonary arterial hypertensiontoll-like receptor 4vasoconstriction

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