The Role of Cyclooxygenase-2 in Podocyte Injury in Diabetic Nephropathy
The Role of Cyclooxygenase-2 in Podocyte Injury in Diabetic Nephropathy
批准号:
7780070
负责人:
RAYMOND C. HARRIS
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-04-01 至 2013-09-30
关键词:
AblationAccountingAdriamycin PFSAdverse effectsAlbuminuriaAngiotensin IIAnimal ModelAwarenessBenefits and RisksBlood PressureBlood VesselsCaringCell LineCellsCharacteristicsClinicalCoxibsDevelopmentDiabetes MellitusDiabetic NephropathyDialysis procedureDiseaseEconomic BurdenEnd stage renal failureEquilibriumExperimental Animal ModelFibrosisGeneticGenetically Engineered MouseGlucoseGoalsHealthHumanHypertensionIn VitroIndividualInflammationInjuryKidneyKidney DiseasesKnockout MiceLeadLinkMacula densaMediatingMediator of activation proteinMedicalModelingMusNephritisPatientsPlayPopulationPredispositionPrevalenceProcessProductionProstaglandin InhibitionProstaglandinsProteinuriaPuromycinRattusReactive Oxygen SpeciesRenal functionRenal glomerular diseaseReninRenin-Angiotensin SystemResearch DesignRiskRoleSignal TransductionSodium ChlorideSourceStreptozocinStructureSyndromeSystemTestingTransgenic MiceTransplantationUnited StatesUp-RegulationVeteransWaterWild Type Mouseabstractingcardiovascular risk factorcell injuryclinically relevantcyclooxygenase 2diabeticexperiencehemodynamicsin vivoinhibitor/antagonistinterstitial celloverexpressionpodocytepreventprorenin receptorprotective effectreceptorreceptor upregulationresponseresponse to injurysalt sensitivetherapeutic developmenttherapeutic target
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海外基金