FASEB SRC on Signal Transduction in the Immune System

 描述（由申请人提供）：本申请寻求FASEB科学研究会议（SRC）的部分资金，该会议将于2015年6月7日至12日在蒙大拿州的大天空举行。本次会议的主要目标是全面关注有关健康和疾病中免疫细胞反应的信号机制的最新进展。2015年的会议将是FASEB会议的第8次会议。这次会议已经在研究机构，学术界和工业界引起了广泛的兴趣，因为杰出的发言者名单，所提出的工作的前沿性和许多演讲与免疫疾病的相关性。此外，由于大多数主流免疫学会议不提供对信号转导机制的深入关注，这个专门的FASEB会议吸引了全球免疫信号转导领域的领导者，以及新的研究人员和学生。因此，本次FASEB会议是FASEB SRC最受欢迎的会议之一。计划于2015年举行的会议包括联合强调适应性（34位发言者中的22位）和先天性（34位发言者中的12位）免疫信号机制。2015年的会议重点关注先天淋巴细胞，包括自然杀伤细胞，先天感应，淋巴细胞活化和分化，细胞活化和分化的成像，免疫缺陷，以及调节白细胞活化和迁移的细胞骨架变化。这些主题代表了免疫信号传导，生物学和人类疾病翻译交叉研究的前沿。会议有一个骨干的定期与会者和发言者，但我们将确保新的想法和领域是在2015年由17个新的发言者（34）。此外，大多数会议都有空间从摘要中选择两个简短的演讲（总共10个简短的演讲），优先考虑西北研究人员，博士后研究员和来自PI不在场的团体的学生。这将确保会议议题的多样性。会议的总体目标是：1提供一个关键的和密集的概述免疫信号的最新进展; 2。将资深科学家和年轻研究人员聚集在一起，在欢乐的气氛中进行非正式讨论，以提高学生和年轻研究人员的技能;通过广泛传播信息和最新突破，推进免疫系统分子机制的研究。我们预计，这次会议将建立在过去的会议在影响免疫信号研究的方向的成功。

 DESCRIPTION (provided by the applicant): This application seeks partial funding for a FASEB Science Research Conference (SRC) on "Signal Transduction in the Immune System", to be held June 7-12, 2015 in Big Sky, Montana. The major goal of this conference is to provide a comprehensive focus on recent advances regarding the signaling mechanisms involved in the response of immune cells in both health and disease. The meeting in 2015 will be the 8th occurrence of this FASEB conference. This conference has garnered widespread interest in research institutes, academia, and industry because of the outstanding speaker rosters, the cutting edge nature of the work presented and the relevance of many presentations to immunologic diseases. Additionally, since most mainstream immunology meetings do not provide an in-depth focus on signal transduction mechanisms, this dedicated FASEB conference has attracted leaders in immune signal transduction world-wide, as well as new investigators and students. As a result, this FASEB conference has been one of the most highly attended FASEB SRC. The meeting planned for 2015 includes a joint emphasis on adaptive (22 out of 34 speakers) and innate (12 out of 34 speakers) immune signaling mechanisms. The 2015 conference includes a strong focus on innate lymphoid cells, including natural killer cells, innate sensing, lymphocyte activation and differentiation, imaging of cell activation and differentiation, immune deficiencies, and cytoskeletal changes that regulate leukocyte activation and migration. These topics represent the cutting edge of research at the intersection of immune signaling, biology and translation to human disease. The conference has a backbone of regular attendees and speakers, but we will ensure that new ideas and areas are addressed in 2015 by featuring 17 new speakers (out of 34). In addition, most sessions have space for two short talks (for a total of 10 short talks) to be selected from abstracts, with priority given to nw investigators, post-doctoral fellows and students from groups in which PIs are not presenting. This will ensure a diversity of topics at the meeting. The overall objectives of the meeting are: 1 To provide a critical and intensive overview of the recent advances in immune signaling; 2. To bring together senior scientists and young investigators in a convivial atmosphere with informal discussions to promote the skills of students and young investigators; 3. To advance research on the molecular mechanisms in the immune system by broadly disseminating information and recent breakthroughs. We anticipate that this conference will build upon the success of past conferences in influencing the direction of immune signaling research.