FASEB SRC on Signal Transduction in the Immune System

FASEB SRC 关于免疫系统信号转导

• 批准号: 8908479
• 负责人: ARTHUR WEISS
• 金额: $ 0.7万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-05-01 至 2016-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8908479
• 关键词: Academia; Address; Affect; Antigen Receptors; Area; Autoimmune Diseases; Autoimmune Process; Biochemical; Biological; Biology; Cells; Clinic; Development; Discipline; Disease; Ensure; Fostering; Funding; Gender; Genetic; Goals; Health; Human; Immune; Immune Cell Activation; Immune System Diseases; Immune response; Immune system; Immunobiology; Immunodeficiency and Cancer; Immunologics; Immunology; Immunotherapy; Industry; Inflammation; Inflammatory; Investigation; Joints; Knowledge; Lymphocyte Activation; Lymphoid Cell; Mainstreaming; Molecular; Montana; Mus; Natural Killer Cells; Nature; Outcomes Research; Pathway interactions; Pharmacologic Substance; Postdoctoral Fellow; RNA; Receptor Signaling; Research; Research Institute; Research Personnel; Science; Scientist; Senior Scientist; Series; Signal Pathway; Signal Transduction; Signal Transduction Pathway; Signaling Molecule; Students; Translations; Vertebral column; Work; abstracting; adaptive immunity; base; biological systems; cellular imaging; combat; human disease; immune function; in vivo imaging; insight; interest; leukocyte activation; mathematical model; meetings; migration; novel therapeutics; planetary Atmosphere; public health relevance; skills; success; symposium; therapeutic target

 DESCRIPTION (provided by the applicant): This application seeks partial funding for a FASEB Science Research Conference (SRC) on "Signal Transduction in the Immune System", to be held June 7-12, 2015 in Big Sky, Montana. The major goal of this conference is to provide a comprehensive focus on recent advances regarding the signaling mechanisms involved in the response of immune cells in both health and disease. The meeting in 2015 will be the 8th occurrence of this FASEB conference. This conference has garnered widespread interest in research institutes, academia, and industry because of the outstanding speaker rosters, the cutting edge nature of the work presented and the relevance of many presentations to immunologic diseases. Additionally, since most mainstream immunology meetings do not provide an in-depth focus on signal transduction mechanisms, this dedicated FASEB conference has attracted leaders in immune signal transduction world-wide, as well as new investigators and students. As a result, this FASEB conference has been one of the most highly attended FASEB SRC. The meeting planned for 2015 includes a joint emphasis on adaptive (22 out of 34 speakers) and innate (12 out of 34 speakers) immune signaling mechanisms. The 2015 conference includes a strong focus on innate lymphoid cells, including natural killer cells, innate sensing, lymphocyte activation and differentiation, imaging of cell activation and differentiation, immune deficiencies, and cytoskeletal changes that regulate leukocyte activation and migration. These topics represent the cutting edge of research at the intersection of immune signaling, biology and translation to human disease. The conference has a backbone of regular attendees and speakers, but we will ensure that new ideas and areas are addressed in 2015 by featuring 17 new speakers (out of 34). In addition, most sessions have space for two short talks (for a total of 10 short talks) to be selected from abstracts, with priority given to nw investigators, post-doctoral fellows and students from groups in which PIs are not presenting. This will ensure a diversity of topics at the meeting. The overall objectives of the meeting are: 1 To provide a critical and intensive overview of the recent advances in immune signaling; 2. To bring together senior scientists and young investigators in a convivial atmosphere with informal discussions to promote the skills of students and young investigators; 3. To advance research on the molecular mechanisms in the immune system by broadly disseminating information and recent breakthroughs. We anticipate that this conference will build upon the success of past conferences in influencing the direction of immune signaling research.

 描述(由申请者提供)：本申请寻求为2015年6月7日至12日在蒙大拿州大天空举行的FASE B科学研究会议(SRC)提供部分资金，会议主题为“免疫系统中的信号转导”。本次会议的主要目标是全面关注在健康和疾病中涉及免疫细胞反应的信号机制的最新进展。2015年的会议将是本届FASEB会议的第8次。这次会议引起了研究机构、学术界和工业界的广泛兴趣，因为有出色的演讲者名单，所做工作的尖端性质，以及许多演讲与免疫学疾病的相关性。此外，由于大多数主流免疫学会议没有提供对信号转导机制的深入关注，这次专门的FASE B会议吸引了世界各地免疫信号转导领域的领导者以及新的研究人员和学生。因此，这次FASEB会议一直是FASEB SRC出席人数最多的会议之一。计划于2015年举行的会议包括联合强调适应性(34名发言者中的22名)和先天免疫信号机制(34名发言者中的12名)。2015年的会议包括对先天性淋巴样细胞的强烈关注，包括自然杀伤细胞、先天性感知、淋巴细胞激活和分化、细胞激活和分化的成像、免疫缺陷以及调节白细胞激活和迁移的细胞骨架变化。这些主题代表了免疫信号、生物学和人类疾病转化研究的前沿。这次会议有一批定期出席者和演讲者，但我们将确保在2015年通过17名新演讲者(34人中)来讨论新的想法和领域。此外，大多数会议有空间从摘要中选择两个简短的演讲(总共10个简短的演讲)，优先考虑西北地区的研究人员、博士后研究员和不参加个人投资的小组的学生。这将确保会议议题的多样性。会议的总体目标是：1.对免疫信号的最新进展提供关键和深入的概述；2.通过非正式讨论，将资深科学家和年轻研究人员聚集在一起，在愉快的气氛中促进学生和年轻研究人员的技能；3.通过广泛传播信息和最新突破，推进免疫系统分子机制的研究。我们预计，这次会议将在以往会议的成功基础上，影响免疫信号研究的方向。