Remote Neuropsychological Assessment: A Proof-of-Concept Test

远程神经心理学评估：概念验证测试

• 批准号: 8856540
• 负责人: Julie A Fiez
• 金额: $ 22.87万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-06-01 至 2018-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8856540
• 关键词: Adopted; Adult; Affective; Aphasia; Basic Science; Behavioral; Benchmarking; Brain; Clinical; Clinical Research; Cognitive; Communication impairment; Computer software; Country; Data; Development; Diagnostic; Effectiveness; Equipment; Failure; Health; Home environment; Instruction; Intervention; Interview; Laboratory Research; Language; Lead; Left; Lesion; Measures; Methods; Monitor; Neurologic; Neuropsychological Tests; Outcome; Participant; Patients; Performance; Persons; Phase; Population; Protocols documentation; Questionnaires; Research; Research Personnel; Self-Administered; Signal Transduction; Stroke; Structure-Activity Relationship; Survivors; Tablet Computer; Technology; Test Result; Testing; Time; Travel; Treatment outcome; United States; Videoconferences; Videoconferencing; Visit; Wireless Technology; base; computerized; data acquisition; design; disability; flexibility; geographically distant; innovation; meetings; neuropsychological; post stroke; satisfaction; stroke recovery; success; tool; usability; virtual

DESCRIPTION (provided by applicant): Stroke is a leading cause of adult disability with a large portion of stroke survivors confronting a communication disorder that significantly diminishes the quality of their lives. Clinical and basic researchers rely upon neuropsychological testing to evaluate the neurologic and behavioral status of stroke survivors. The difficulties involved in obtaining neuropsychological data hinder basic and clinical research involving this population. This proposal responds to the need for innovative approaches to neuropsychological testing. Standard neuropsychological test administration relies upon face-to-face (F2F) interactions. This imposes geographic constraints and data acquisition burdens that reduce research efficiency and lead to disparities in research involvement. To overcome these barriers, we will develop tools and protocols that will allow stroke survivors to complete neuropsychological tests in their own homes, through the virtual support of a geographically distant investigator. We will use wireless collaborative videoconferencing software and easy-to-operate tablet computers (iPads). Our test battery will probe core language functions and our participants will have left-hemisphere lesions. This initial direction was chosen because the personal and societal burden of post-stroke aphasia is significant, many tasks used for aphasia research are straightforward, prior data permits predictions about expected results, and there is a clear need for tools that can monitor aphasia status and treatment outcomes. Formative usability tests of our technology and protocols will be used to optimize the administration of our battery under three different conditions: 1) a virtual, investigator-guided protocol that is designd to emulate standard F2F neuropsychological testing, 2) a virtual, self- administered protocol that is designed to emulate computerized approaches to test administration, and 3) a standard face-to-face protocol that is intended as a performance benchmark. Once our protocols are in place, data will be acquired from three groups of participants with focal left-hemisphere lesions. Each group will complete our battery of language tasks in their home, via one of our two virtual protocols or a standard F2F protocol. All groups will complete a standard F2F protocol in our research laboratory. A variety of usability metrics will be used to evaluate participant and researcher satisfaction, confidence, and success with our virtual protocols. The behavioral data will be used to test whether comparable results are obtained when our tasks are administered under versus F2F testing conditions. Measures of efficiency and equipment reliability will provide a practical perspective on the benefits and limitations of home-based remote neuropsychological assessment. Overall, we aim to develop an innovative method for home-based remote neuropsychological testing that can be readily adapted and adopted by other investigators to meet a diverse set of research needs.

描述（由申请人提供）：中风是成人残疾的主要原因，大部分中风幸存者面临着严重降低生活质量的沟通障碍。临床和基础研究人员依靠神经心理学测试来评估中风幸存者的神经和行为状态。获取神经心理学数据的困难阻碍了涉及这一人群的基础和临床研究。这一建议回应了神经心理学测试创新方法的需求。标准的神经心理学测试管理依赖于面对面（F2F）的互动。这造成了地理限制和数据采集负担，降低了研究效率，并导致研究参与的差异。为了克服这些障碍，我们将开发工具和协议，使中风幸存者能够在自己的家中完成神经心理学测试，通过地理上遥远的研究者的虚拟支持。我们将使用无线协作视频会议软件和易于操作的平板电脑（iPad）。我们的测试组合将探测核心语言功能，我们的参与者将有左半球损伤。之所以选择这个最初的方向，是因为中风后失语症的个人和社会负担是显著的，失语症研究中使用的许多任务是直接的，先前的数据允许对预期结果进行预测，并且明确需要可以监测失语症状态和治疗结果的工具。我们的技术和方案的形成性可用性测试将用于在三种不同条件下优化我们的电池管理：1）被设计为模拟标准F2F神经心理学测试的虚拟的、模拟器引导的协议，2）被设计为模拟计算机化的测试管理方法的虚拟的、自我管理的协议，以及3）旨在作为性能基准的标准面对面协议。一旦我们的协议到位，数据将从三组参与者与局灶性左半球病变。每个小组将通过我们的两个虚拟协议之一或标准F2F协议在他们的家中完成我们的一系列语言任务。所有小组将在我们的研究实验室完成标准的F2F协议。各种可用性指标将用于评估参与者和研究人员的满意度，信心和成功与我们的虚拟协议。行为数据将用于测试当我们的任务在与F2F测试条件下管理时是否获得可比的结果。效率和设备可靠性的措施将提供一个实用的角度对家庭为基础的远程神经心理评估的好处和局限性。总的来说，我们的目标是开发一种创新的方法，以家庭为基础的远程神经心理测试，可以很容易地适应和采用其他研究人员，以满足不同的研究需求。