Career Development

摘要-职业发展计划 马约诊所卵巢癌SPORE的目的是刺激，组织和促进严格的 转化研究，这将有意义地减少卵巢癌的负担。这个过程的关键部分 是为了提高卵巢癌研究的质量和深度。前五个 年的资助，四个人获得了职业发展奖，并得到了1-2年的支持， 资金、指导团队以及对SPORE资源的全面访问。我们的获奖者都非常成功， 出版了14份手稿，另有2份正在审查中，所有手稿都获得了后续资金， (Paul Haluska和Matthew Block）在此次更新申请中共同领导项目; 此外，Haluska博士是动物模型中心的主任。所有获奖者都依赖于 生物标本和生物统计学核心，以发展他们的研究计划; Haluska博士还与 动物模型核心。职业发展计划（CDP）的最终目标仍然是 识别和指导新的和正在发展的卵巢癌研究者， 有潜力成为独立的翻译研究人员，并吸引建立科学家谁愿意 重新关注卵巢癌CDP提供高达100，000美元的一年支持（50，000美元， SPORE基金和来自马约诊所的配套50，000美元）;根据进展情况，第二年是可能的， 连续平移轨迹。重点是吸引高素质的个人 在医学领域，包括妇女和少数民族的代表性不足。识别和选择CDP获奖者是 通过严格的审查程序完成，然后进行密集的辅导，纳入正在进行的 SPORE活动和对个人进展的密切监督。除了一个主要的导师，获奖者 在临床、基础或人口科学方面有必要的补充导师，以确保发展 翻译研究生涯这充分利用了马约环境中存在的众多优势。 CDP向马约诊所卵巢癌孢子执行委员会报告。在下一个 在资助期间，卵巢孢子将继续保持：（1）严格的候选人选拔制度;（2） 由初级指导员对受训人员进行全面指导;（3）通过科学指导小组（ 个别学员指导委员会），由在每个学员领域具有专业知识的调查员组成， 兴趣;（4）完全融入SPORE，包括访问所有科学核心。马约诊所提供 一个特殊的环境，发展卵巢癌转化研究的职业生涯。中国民主党党内 使我们能够识别，指导和支持年轻的研究人员，他们将成为卵巢癌的未来领导者 research.

ABSTRACT – Career Development Program The purpose of the Mayo Clinic SPORE in Ovarian Cancer is to stimulate, organize and facilitate rigorous translational research that will meaningfully reduce the burden of ovarian cancer. A critical part of this process is to increase the quality and depth of the translational investigator base in ovarian cancer. During the first five years of funding, four individuals received Career Development Awards and were supported with 1-2 years of funding, mentoring teams, and full access to SPORE resources. Our awardees have been highly successful, with 14 manuscripts published and an additional 2 under review, all receiving subsequent funding and two (Paul Haluska and Matthew Block) advancing to co-leadership of projects in this renewal application; additionally, Dr. Haluska is the Director of the Animal Models Core. All awardees relied upon the Biospecimens and Biostatistics Cores to develop their research programs; Dr. Haluska also partnered with the Animal Models Core. The ultimate objectives of the Career Development Program (CDP) continue to be the identification and mentoring of new and developing investigators in ovarian cancer who demonstrate clear potential to become independent translational researchers as well as attracting established scientists who wish to refocus on ovarian cancer. The CDP provides up to $100,000 for one year of support ($50,000 from SPORE funds and a matching $50,000 from Mayo Clinic); a second year is possible based on progress and continued translational trajectory. Emphasis is placed on attracting highly qualified individuals underrepresented in medicine, including women and minorities. Identifying and selecting CDP awardees is accomplished through a rigorous review process, followed by intense mentoring, integration into ongoing SPORE activities and close oversight of the individual's progress. In addition to a primary mentor, awardees have complementary mentors in clinical, basic or population sciences necessary to ensure development of a translational research career. This capitalizes on numerous strengths present within the Mayo environment. The CDP reports to the Executive Committee of the Mayo Clinic Ovarian Cancer SPORE. During the next funding period, the Ovarian SPORE will continue to maintain: (1) a stringent candidate selection system; (2) comprehensive trainee guidance by a primary mentor; (3) support through a scientific mentoring group (the Individual Trainee Mentorship Committee) comprised of investigators with expertise in each trainee`s area of interest; and (4) full integration into the SPORE, including access to all scientific Cores. Mayo Clinic provides an exceptional environment for developing careers in translational research in ovarian cancer. The CDP allows us to identify, mentor, and support young investigators who will become future leaders in ovarian cancer research.