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中文摘要
翻译
爱荷华州神经内分泌肿瘤孢子的发展研究计划的目标是带来新的 思想和创新技术,以承担诊断,治疗性治疗,并最终,预防 神经内分泌肿瘤发展研究计划将提供高达50,000美元的一年 (25,000美元来自SPORE基金,25,000美元来自机构资源), 第二年的支助可能根据进展情况提供。预计, 发展研究项目将继续产生新的假设并进行测试 通过SPORE赞助的项目或通过同行评审的外部赠款支持。的长期目标 爱荷华州神经内分泌肿瘤孢子计划是翻译的发展项目产生的结果 改善神经内分泌肿瘤患者的寿命和生活质量。更具体而言是 发展研究计划的目标是:(1)鼓励创新的翻译人口, 实验室和临床研究的神经内分泌肿瘤;(2)促进基础之间的广泛合作 神经内分泌肿瘤转化研究中的科学、人口科学和临床学科;和,(3) 产生新的假设,在大规模的研究项目或临床试验中进行测试,可能导致 显著降低神经内分泌肿瘤的发病率和死亡率。简要概述三种可能性 包括发展研究项目,以展示正在进行的研究的深度和广度, 可应用于神经内分泌肿瘤的转化研究,并符合爱荷华州 神经内分泌肿瘤孢子发育计划支持。 �
英文摘要
The goal of the Developmental Research Program in the Iowa Neuroendocrine Tumor SPORE is to bring new ideas and innovative techniques to bear on the diagnosis, curative therapy, and ultimately, the prevention of neuroendocrine tumors. The Developmental Research Program will provide up to $50,000 for one year ($25,000 from SPORE funds and a matching $25,000 from institutional resources) to each of two projects each year with the possibility of a second year of support based on progress. It is anticipated that support of developmental research projects will continue to result in the generation of new hypotheses that will be tested in full SPORE-sponsored projects or through peer reviewed external grant support. The long-term goal of the Iowa Neuroendocrine Tumor SPORE program is to translate the findings generated by developmental projects into an improved length and quality of life for patients with neuroendocrine tumors. More specifically, the objectives of the Developmental Research Program are to: (1) encourage innovative translational population, laboratory, and clinical studies in neuroendocrine tumors; (2) foster extensive collaboration between basic science, population science and clinical disciplines in translational research in neuroendocrine tumors; and, (3) generate new hypotheses to be tested in large-scale research projects or clinical trials that may lead to significant reduction in incidence and mortality of neuroendocrine tumors. Brief outlines of three potential developmental research projects are included to demonstrate the depth and breadth of ongoing research that can be applied to the translational research in neuroendocrine tumors and would be eligible for Iowa Neuroendocrine Tumor SPORE Developmental Program support. �
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Project 2: Exploiting Labile Iron Pools for Improving NSCLC Therapy Using Pharmacological Ascorbate
  • 批准号:
    10240531
  • 项目类别:
  • 资助金额:
    $47.73万
  • 财政年份:
    2018
  • 负责人:
    Douglas Robert Spitz
  • 依托单位:
Project 2: Exploiting Labile Iron Pools for Improving NSCLC Therapy Using Pharmacological Ascorbate
  • 批准号:
    10005908
  • 项目类别:
  • 资助金额:
    $47.73万
  • 财政年份:
    2018
  • 负责人:
    Douglas Robert Spitz
  • 依托单位:
Enhancing Metabolic Oxidative Stress and Therapy Responses in Cancer Stem Cells
  • 批准号:
    8623548
  • 项目类别:
  • 资助金额:
    $33.84万
  • 财政年份:
    2013
  • 负责人:
    Douglas Robert Spitz
  • 依托单位:
Enhancing Metabolic Oxidative Stress and Therapy Responses in Cancer Stem Cells
  • 批准号:
    8776281
  • 项目类别:
  • 资助金额:
    $33.84万
  • 财政年份:
    2013
  • 负责人:
    Douglas Robert Spitz
  • 依托单位:
海外基金