PARACAS: Program for Advanced Research Capacities for AIDS in Peru

PARACAS：秘鲁艾滋病高级研究能力计划

• 批准号: 8910798
• 负责人: Eduardo Gotuzzo
• 金额: $ 30.28万
• 依托单位: UNIVERSIDAD PERUANA CAYETANO HEREDIA
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-11 至 2019-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8910798
• 关键词: AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Address; Adolescent; Adult; Alabama; Behavioral Sciences; Caring; Child; Chronic; Collaborations; Community Health; Evidence based intervention; Family; Fostering; Generations; HIV; Health; Health Services; Individual; Infection; Intervention; Leadership; Learning; Life; Medical Students; Mentors; Modeling; Multidrug-Resistant Tuberculosis; Output; Peru; Physicians; Positioning Attribute; Process; Research; Research Personnel; Research Training; Role; Scientist; System; Thinking; Training; Translating; Tuberculosis; Universities; Washington; Work; antiretroviral therapy; base; burden of illness; career; experience; implementation science; improved; programs; sound

DESCRIPTION (provided by applicant): The overall aim of our Program for Advanced ReseArch Capacities for AIDS in Peru (PARACAS) is to consolidate a mature HIV research training framework at Universidad Peruana Cayetano Heredia (UPCH), in which outstanding young or mid-career health researchers will reach scientific autonomy by providing sound evidence for the implementation of optimized and efficient care models that comprehensibly address the fact that HIV is rather a chronic, prolonged condition. Undeniably, health services should foster earlier initiation of antiretroviral therapy (ART) in parallel to increasing retentio in care of people living with HIV/AIDS (PLWHA), as this combination preserves and benefits individual and community health. In that regard, PARACAS' trainees will propose intervention strategies built upon a comprehensive analysis that considers biomedical aspects and multidimensional perspectives related with the processes of entry and retention in care, such as the perspectives of PLWHA (adult, adolescents, and children), of their families, their communities, and the health staff. Accordingly, the proposed interrelated training at US (3 MPH trainees and 2 postdoctoral positions) will be based on two pillars: behavioral sciences for a broad, scientific analysis of those perspectives; and implementation science, to assure that the analysis can be translated to specific evidence-based interventions. Because coexistent tuberculosis (TB) and particularly multidrug resistant TB, frequent in Peru, add burden of disease to PLWHA, our PARACAS will also address the role of these infections as barriers for early entry and retention in care. As PARACAS stands as an initiative that follows the successful collaboration of three universities, Universidad Peruana Cayetano Heredia (UPCH), the University of Washington (UW) in Seattle, and the University of Alabama at Birmingham (UAB), long-standing academic outputs are also envisioned. PARACAS will enable mentoring systems and promote "transformative learning" by means of fostering the "thinking critically ahead" model and stimulating the interaction, leadership, and team work of trainees with complementary expertise and different level of experience, even advanced undergraduate medical students (tandem research groups). These strategies should serve to nurture new incoming generations of physician scientists whose contributions should continue notoriously improving the lives of PLWHA.

描述(由申请人提供)：我们秘鲁艾滋病高级研究能力计划(PARACAS)的总体目标是巩固Peruana Cayetano Heredia大学(UPCH)成熟的艾滋病毒研究培训框架，在该框架中，杰出的年轻或职业生涯中期的卫生研究人员将通过提供可靠的证据，实现科学自主，实施优化和有效的护理模式，全面解决艾滋病毒是一种慢性、长期性疾病的事实。不可否认，卫生服务应在增加对艾滋病毒/艾滋病患者的护理的同时，促进更早地启动抗逆转录病毒疗法(ART)，因为这种结合保护并有利于个人和社区的健康。在这方面，帕拉卡斯的受训人员将在综合分析的基础上提出干预战略，其中考虑到与进入和保留护理过程有关的生物医学方面和多方面的观点，例如PLWHA(成人、青少年和儿童)、他们的家庭、他们的社区和卫生工作人员的观点。因此，美国拟议的相关培训(3英里/小时受训人员和2个博士后职位)将基于两个支柱：行为科学，以对这些观点进行广泛、科学的分析；以及实施科学，以确保分析可以转化为具体的循证干预措施。由于共存的结核病，特别是在秘鲁频繁出现的耐多药结核病，增加了PLWHA的疾病负担，我们的Paracas还将解决这些感染作为及早进入和保留在护理中的障碍的作用。由于Paracas是继三所大学--佩鲁阿纳卡耶塔诺大学(UPCH)、西雅图华盛顿大学(UW)和阿拉巴马大学伯明翰分校(UAB)--成功合作后提出的一项倡议，因此也展望了长期的学术成果。PARACAS将通过促进“批判性超前思考”模式，促进具有互补专业知识和不同经验水平的受训者的互动、领导力和团队合作，甚至是高级医科本科生(串联研究小组)，支持指导系统和促进“变革性学习”。这些战略应该有助于培养新一代的内科科学家，他们的贡献应该继续臭名昭著地改善PLWHA的生活。