Program for Advanced ReseArch Capacities for AIDS in Peru (PARACAS): harnessing implementation science to enhance care and reduce transmission of HIV

2007年，我们获得了Fogarty ICOHRTA赠款奖，用于开展艾滋病毒和结核病研究 在秘鲁卡耶塔诺埃雷迪亚大学（UPCH）的培训计划。2014年，我们现在的"PARACAS" （秘鲁艾滋病高级研究能力方案）使我们能够进一步整合艾滋病毒 对UPCH文化的研究以及与华盛顿大学（UW）的成熟合作， 位于伯明翰的亚拉巴马大学。通过密切指导的研究，沿着选择 课程工作，优秀的年轻和职业中期健康研究人员正在达到科学熟练程度 这将使他们能够共同应对新出现的艾滋病毒挑战。 根据国家卫生研究院、秘鲁卫生部和联合国艾滋病规划署的研究重点， 我们的PARACAS的更新申请加强了对实施科学的关注，以改善艾滋病毒 继续提供护理，扩大对孕产妇艾滋病毒的护理和消除儿童艾滋病毒的努力。在 在高质量指导的背景下，我们的目标是：1）刺激关键的研究职业发展， 通过硕士（3）、博士（2）和博士后（2），科学地产生选定的顶尖候选人 奖学金; 2）巩固作为一个中心，为有前途的医学本科生（8）早日进入长期- 长期高级艾滋病毒研究培训;和3）通过加强艾滋病毒护理政策变化的影响， 与政府利益攸关方进行知识中介。 我们的PARACAS研究培训计划的本质-"变革，协作学习"- 利用它的影响超出了对个别学员的好处。刺激和促进长期职业生涯 在艾滋病毒研究方面，这种更新应用程序（a）整合了合作美国的竞争性课程 在美国和秘鲁PARACAS共同指导下在秘鲁开展研究的机构 教师（长期"三明治"培训），与（B）实际指导的研究选修课。这些培训 这些努力将通过全球卫生研究员计划和新的 最近为在国外获得博士学位的候选人提供了长期研究-职业补助金 秘鲁政府。即使我们的培训生选拔过程将继续针对候选人， 高潜力的研究取得成功，我们将加强个性化的指导和灵活性， 培训形式，有利于征聘、业绩和保留在下列领域任职人数偏低的受训人员 科学，尤其是女性。 到这个时候，大大丰富了校友先前ICOHRTA和PARACAS赠款谁是 在UPCH和秘鲁卫生部内建立，我们的PARACAS更新提供了广泛的 指导能力和教师专业知识的广度，继续获得一个充满活力的，新的人才库， 秘鲁受训人员，以有效地促进实现无艾滋病一代的目标。

In 2007, we received a Fogarty ICOHRTA grant award to launch an HIV and tuberculosis research training program at the Universidad Peruana Cayetano Heredia (UPCH). In 2014, our current “PARACAS” (Program for Advanced ReseArch Capacities for AIDS in Peru) allowed us to further integrate HIV research into the culture of UPCH and mature collaborations with the University of Washington (UW) and the University of Alabama at Birmingham (UAB). Through closely mentored research, along selected course work, outstanding young and mid-career health researchers are reaching the scientific proficiency and leadership that will allow them to jointly address emerging HIV challenges. In alignment with research priorities of the NIH, the Peruvian Ministry of Health and UNAIDS targets, this renewal application for our PARACAS strengthens the focus upon implementation science to improve HIV retention in care, expanding efforts towards the care of maternal HIV and elimination of pediatric HIV. In the context of high-quality mentoring, we aim to: 1) stimulate the critical research career development and scientific production of selected top candidates through masters (3), doctoral (2) and postdoctoral (2) scholarships; 2) consolidate as a hub for early entry of promising medical undergraduates (8) into long- term advanced HIV research training; and 3) to influence on policy change for HIV care by enhancing knowledge brokering with government stakeholders. The essence of our PARACAS’ research training program - "transformative, collaborative learning" - leverages its impact beyond the benefits to individual trainees. To stimulate and boost long-term careers in HIV research, this renewal application (a) integrates competitive coursework at collaborating US institutions with implementation of research in Peru under co-mentoring of US and Peruvian PARACAS faculty (long-term “sandwich” training), with (b) practical mentored research electives. These training efforts will be complemented by mentorship training through the Global Health Fellows Program and novel long-term research-career grants for candidates with doctoral degrees obtained abroad recently launched by the Peruvian Government. Even if our trainee selection process will continue to target candidates with high potential to succeed in research, we will reinforce the individualized mentoring and flexibility of training formats that benefit recruitment, performance and retention of trainees underrepresented in science, particularly women. By this time substantially enriched with alumni of the prior ICOHRTA and PARACAS grants who are established within UPCH and the Peruvian Ministry of Health, our PARACAS renewal offers the extensive mentoring capacities and breadth of faculty expertise, continued access to a vibrant, talent pool of new Peruvian trainees, to effectively contribute to the goal of achieving an AIDS-free generation.