Model Based Approach to Improving Hypertension Control in Populations

基于模型的方法改善人群高血压控制

• 批准号: 9173941
• 负责人: Andrew Edward Moran
• 金额: $ 63.46万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-01 至 2020-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9173941
• 关键词: Achievement; Address; Adherence; Adoption; Adult; Affect; Age; Antihypertensive Agents; Awareness; Benchmarking; Biometry; Blood Pressure; California; Cardiovascular Diseases; Caring; Categories; Cause of Death; Cessation of life; Characteristics; Chronic; Clinic Visits; Clinical Practice Guideline; Clinical Trials; Clinical effectiveness; Computer Simulation; Computerized Medical Record; Cost Savings; Data; Decision Making; Effectiveness; Eligibility Determination; Ethnic group; Event; Goals; Guidelines; Head; Health; Health Benefit; Healthcare; Home Blood Pressure Monitoring; Home environment; Hospitalization; Hypertension; Hypotension; Individual; Intervention; Intervention Trial; Investments; Lead; Los Angeles; Louisiana; Measurement; Medicare; Medicare claim; Modeling; Monitor; New York; Patient risk; Patients; Performance; Pharmaceutical Preparations; Policies; Population; Process; Provider; Publishing; Quality of Care; Race; Reporting; Research Proposals; Resources; Risk; Risk Factors; Speed; Surveys; Test Result; Time; United States; aged; base; blood pressure reduction; blood pressure regulation; cardiovascular disorder risk; cardiovascular health; clinical practice; comparative effectiveness; control trial; cost; cost effective; cost effectiveness; design; economic evaluation; financial incentive; health economics; health organization; high risk; hypertension control; hypertension treatment; implementation trial; improved; indexing; modifiable risk; patient population; payment; pill; population health; prevent; programs; sex; simulation; treatment as usual; treatment trial

Project Summary Hypertension is the leading preventable risk factor for cardiovascular disease (CVD) in the United States. In about 28 million adults with hypertension, blood pressure is not controlled to recommended treatment goals. Because inexpensive, safe, and effective medications are available, uncontrolled hypertension is a missed opportunity to improve the health of the U.S. population. For this project, we assembled a team of experts in hypertension, biostatistics, clinical trials, health economic evaluation, and computer simulation modeling in order to evaluate the incremental value of implementing two types of hypertension control programs studied in clinical trials: team-based care and home blood pressure monitoring. Analyses of published and individual-level clinical trial and computer simulation will be used to model, in U.S. adults • The comparative effectiveness (number of prevented CVD events and deaths) and cost-effectiveness of different hypertension control approaches, alone or in combination, in all U.S. adults and within age categories, race/ethnic groups, and CVD risk categories • The comparative effectiveness and cost-effectiveness different hypertension control programs in patients with uncontrolled hypertension in three Medicare Accountable Care Organizations (New York Quality Care, Ochsner Accountable Care, and Cedars-Sinai Accountable Care) • The comparative effectiveness and cost-effectiveness of implementing a 120 mmHg systolic BP goal in high risk U.S. adults aged ≥50 years according to Systolic Blood Pressure Intervention Trial (SPRINT) eligibility Relevance The results of these analyses have the potential to improve the quality of hypertension treatment in routine clinical practice, which may lead to improved cardiovascular health in the U.S. population.

项目总结