The International Primary Sclerosing Chonagitis Study Group Meeting

项目摘要：本申请寻求对两年一度的国际小学的支持 硬化性胆管炎研究小组会议将于6月26日在康涅狄格州纽黑文举行 2016年和27日。这次会议的主要目标是首次在 北美，世界学术思想领袖对初级硬化术感兴趣 胆管炎。本次会议将集中讨论这种孤儿疾病尚未得到满足的主要研究需求。 目前尚无明确的病因和有效的治疗方法。PSC中的关键知识差距将 应解决的问题包括：1)代理和患者报告的结果；2)整合 PSC的病理生理机制；3)PSC中胆管细胞癌的定义，包括基础 机制、早期发现和治疗策略；4)PSC的新疗法。进展 目前正在进行的研究活动将由几个“工作组”报告。这是我们的希望 这次会议将成为促进多中心发展的主要刺激因素 北美学术中心针对这种疾病的合作研究项目。这个 会议也是史无前例的，因为它将与PSC合作伙伴的年度会议重叠 寻求治疗(PSCPSC)，一个卓越的、全国性的以患者为本的组织 这一疾病为制定与患者相关的结果提供了独特的机会。

Project Summary: This application seeks support for the biennial International Primary Sclerosing Cholangitis Study Group (IPSCSG) meeting to be held in New Haven, CT, on June 26 and 27th 2016. The primary objective of this conference is to bring together for the first time, in North America, the world's academic thought leaders interested in Primary Sclerosing Cholangitis. This conference will focus on primary unmet research needs in this orphan disease for which there is no know etiology or effective treatment. Critical Knowledge Gaps in PSC will be addressed including: 1) Surrogate and Patient Reported Outcomes; 2) Integrating Pathophysiologic Mechanisms of PSC; 3) Defining Cholangiocarcinoma in PSC, including basic mechanisms, early detection and treatment strategies; and 4) New Therapies in PSC. Progress in current ongoing research activities will be reported by several “working groups”. It is our hope that this meeting will serve as a primary stimulus to foster the development of multicenter collaborative research projects for this disease by North American Academic Centers. The meeting is also unprecedented as it will overlap with the annual meeting of the PSC Partners Seeking a Cure (PSCPSC), the preeminent and nationwide lay patient oriented organization for this disease, providing a unique opportunity for the development of patient related outcomes.