The International Primary Sclerosing Chonagitis Study Group Meeting

国际原发性硬化性胆管炎研究组会议

• 批准号: 9187570
• 负责人: JAMES Lorenzen BOYER
• 金额: $ 2.3万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-06-20 至 2017-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9187570
• 关键词: Address; American; Cholangiocarcinoma; Development; Disease; Early Diagnosis; Early treatment; Etiology; Fostering; Group Meetings; International; Knowledge; North America; Outcome; Patient Outcomes Assessments; Patients; Rare Diseases; Reporting; Research; Research Activity; Research Project Grants; Sclerosis; Stimulus; Time; United States; effective therapy; interest; meetings; novel therapeutics; patient oriented; primary sclerosing cholangitis; symposium; treatment strategy; working group

Project Summary: This application seeks support for the biennial International Primary Sclerosing Cholangitis Study Group (IPSCSG) meeting to be held in New Haven, CT, on June 26 and 27th 2016. The primary objective of this conference is to bring together for the first time, in North America, the world's academic thought leaders interested in Primary Sclerosing Cholangitis. This conference will focus on primary unmet research needs in this orphan disease for which there is no know etiology or effective treatment. Critical Knowledge Gaps in PSC will be addressed including: 1) Surrogate and Patient Reported Outcomes; 2) Integrating Pathophysiologic Mechanisms of PSC; 3) Defining Cholangiocarcinoma in PSC, including basic mechanisms, early detection and treatment strategies; and 4) New Therapies in PSC. Progress in current ongoing research activities will be reported by several “working groups”. It is our hope that this meeting will serve as a primary stimulus to foster the development of multicenter collaborative research projects for this disease by North American Academic Centers. The meeting is also unprecedented as it will overlap with the annual meeting of the PSC Partners Seeking a Cure (PSCPSC), the preeminent and nationwide lay patient oriented organization for this disease, providing a unique opportunity for the development of patient related outcomes.

项目概要：此申请旨在支持两年一度的国际小学 硬化性胆管炎研究小组（IPSCSG）会议将于6月26日在康涅狄格州纽黑文举行 2016年第27届。本次会议的主要目标是首次汇集， 北美，世界学术思想领袖对原发性硬化感兴趣 胆管炎本次会议将重点关注这一孤儿病的主要未满足的研究需求 其病因不明，治疗方法也不有效。PSC中的关键知识差距将 包括：1）代理人和患者报告的结局; 2）整合 PSC的病理生理机制; 3）定义PSC中的胆管癌，包括基础 机制、早期发现和治疗策略;以及4）PSC的新疗法。进展 目前正在进行的研究活动将由几个“工作组”报告。我们希望 本次会议将作为促进多中心发展的主要动力， 北美学术中心对这种疾病的合作研究项目。的 这次会议也是前所未有的，因为它将与PSC合作伙伴的年度会议重叠 寻求治愈（PSCPSC），卓越的和全国性的奠定面向患者的组织， 这种疾病，为患者相关结果的发展提供了独特的机会。