Training Grant in Gastrointestinal Physiology and Psychology

描述(由申请人提供)：该项目的目标是利用生理学和心理学的专业知识和西北大学现有的资源，培养生物医学工程和心理学的博士后学生，以及胃肠病、外科和心理学的医学博士和博士后实习生，从事功能性前肠疾病的研究。对功能性和运动性前肠功能障碍的研究是复杂的，需要多学科的方法，其中包括对胃肠道功能的机械、生理和炎症方面的了解，以及改变症状反应的认知和心理社会因素。这项培训计划将建立在西北大学食道中心和心理社会研究中心的成功整合的基础上，并利用目前与医疗研究中心、认知脑成像小组以及过敏免疫学和病理学领域的翻译研究同事的合作资源。胃肠病学和肝脏病学的奖学金、外科的住院医师计划以及工程学和心理学的研究生计划吸引了这些培训职位的顶尖申请者。每个受训者将与一名主要研究导师和一名共同导师合作，这将促进研究和临床教师之间的互动，并加强受训者研究经验的合作方面。已经制定了一个培训计划，包括结构化研究和导师，结合临床调查或公共卫生领域的理学硕士，研讨会，职业发展计划，以及研究道德行为方面的教育，以促进专注于功能性前肠疾病的研究的卓越。我们建议每年资助一名高资质博士后学生和一名高资质博士后医学博士或博士后实习生进行为期两年的密集研究。因此，我们的计划将有4名学员处于稳定状态，目前我们收到了潜在申请者的兴趣，以及我们潜在导师、部门和大学对支持该计划的承诺。

DESCRIPTION (provided by applicant): The goal of this program is to leverage the physiology and psychology expertise and the current resources available at Northwestern University to train predoctoral students in Biomedical Engineering and Psychology and MD and PhD postdoctoral trainees in Gastroenterology, Surgery and Psychology for careers focused on research in functional foregut disorders. The study of functional and motor foregut disorders is complicated and requires a multidisciplinary approach that incorporates an understanding of the mechanical, physiological and inflammatory aspects of gastrointestinal tract function and the cognitive and psychosocial factors that alter symptom response. This training program will build on the successful integration of the Esophageal Center and Center for Psychosocial Research at Northwestern University and also utilize resources from current collaborations with the Center for Healthcare Studies, the Cognitive Brain Mapping Group and translational research colleagues in Allergy-Immunology and Pathology. The fellowship in Gastroenterology and Hepatology, residency program in Surgery and the graduate programs in Engineering and Psychology attract top-notch applicants for these training positions. Each trainee will work with both a primary research mentor and a co-mentor, which will foster interaction between research and clinical faculty and enhance the collaborative aspects of the trainee's research experience. A training program consisting of structured research and mentorship that combines a Master of Science in Clinical Investigation or Public Health degee, seminars, career development programs, and education in the ethical conduct of research has been developed to promote excellence in research focused on functional foregut disorders. We propose to fund one highly qualified predoctoral student and one highly qualified postdoctoral MD or PhD trainee per year for a two-year intensive research experience. Thus, our program will have 4 trainees at steady-state and currently we have the interest from prospective applicants and commitment from our potential mentors, departments and university to support this program.