FOSTERING INTEGRITY AND SOCIETAL IMPACT IN GENOMICS THROUGH MANAGEMENT AND LEADERSHIP PRACTICES

 描述（由申请人提供）：此K 01提案描述了职业发展活动和研究计划，将促进候选人过渡到基因组科学的伦理，法律的和社会影响（ELSI）领域的独立研究者。的 申请人有工业组织（IO）心理学的背景，其中包括定量方法，研究设计和工作场所心理学的培训。此外，申请人还进行了研究，重点是道德决策，研究道德指导和组织领导。该补助金将为申请人提供额外的必要培训， 生物伦理学，ELSI基因组学，遗传/基因组科学，定性方法，和行为变化/专业发展，通过课程，指导，研讨会和指导阅读的组合。候选人的多学科导师包括在生物伦理学和专业研究和临床遗传研究方面取得学术成就的研究人员。一个由在研究伦理合规、基因组科学、ELSI研究和领导方面具有专业知识的个人组成的咨询委员会将提供额外的指导和指导，以支持候选人的职业发展和研究活动。拟议的研究将有助于ELSI领域，并补充候选人的职业发展培训活动计划。它将联合收割机申请人在工作场所心理学的专业知识与导师和顾问在研究伦理，临床遗传学，基因组学和ELSI基因组学的专业知识相结合，以了解基因组科学家的管理实践和领导实践如何与基因组科学的伦理，法律的和社会成果相关。该研究包括几个具体的目标，将使用多种社会科学研究方法，包括半结构化访谈，调查研究和焦点小组。这些目标包括：（1）使用扎根理论定性方法探索科学家的管理和领导实践与其工作中的伦理、法律的和社会问题之间的具体联系，（2）盘点基因组研究人员当前的管理和领导实践，并确定发展需求，（3）制定和测试针对研究人员的信息，以鼓励他们参与定制的管理和领导计划。通过更好地了解研究人员本身在科学的伦理，法律的和社会成果中发挥作用的方式，这项研究将为候选人的研究生涯做好准备，通过开发基于证据的资源和干预措施来帮助研究人员满足他们工作的各种需求，从而为基因组科学的质量，完整性和社会影响做出贡献。

 DESCRIPTION (provided by applicant): This K01 proposal describes the career development activities and research plan that will facilitate the candidate's transition to an independent investigator in the field of ethical, legal, and social implications (ELSI) in genomic science. The applicant has a background in industrial-organizational (IO) psychology, which includes training in quantitative methods, research design, and workplace psychology. In addition, the applicant has conducted research focused on ethical decision-making, research ethics instruction, and organizational leadership. This grant will provide the applicant with additional needed training in bioethics, ELSI in genomics, genetic/genomic science, qualitative methods, and behavioral change/professional development through a combination of coursework, mentoring, seminars, and guided readings. The candidate's multidisciplinary mentors include researchers with records of academic achievement in bioethics and professionalism in research and in clinical genetic research. An advisory committee of individuals with expertise in research ethics compliance, genomic science, ELSI research, and leadership will provide additional mentorship and guidance to support the career development and research activities of the candidate. The proposed research will contribute to the ELSI field and complement the candidate's plan for career development training activities. It will combine the applicant's expertise in workplace psychology with the mentors' and advisors' expertise in research ethics, clinical genetics, genomic science, and ELSI in genomics to understand how the management practices and leadership practices of genomic scientists relate to the ethical, legal, and social outcomes of genomic science. The research includes several specific aims that will be achieved using multiple social science research methods, including semi-structured interviews, survey research, and focus groups. The aims include: (1) to explore specific connections between management and leadership practices of scientists and ethical, legal, and social issues in their work using a grounded theory qualitative approach, (2) to inventory the current management and leadership practices of genomic researchers and identify development needs, and (3) to develop and test messages targeting researchers to encourage their participation in tailored management and leadership programs. By better understanding the ways in which researchers themselves play a role in the ethical, legal, and social outcomes of science, this research will prepare the candidate for a research career that contributes to the ELSI field by developing evidence-based resources and interventions to help researchers meet the various demands of their work, thereby contributing to the quality, integrity, and social impact of genomic science.