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中文摘要
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核心A -行政核心 CWRU/UH CFAR行政核心负责推动艾滋病毒/艾滋病研究的方向, 我们的机构,同时应对不断变化的研究需求的CFAR调查。的 行政核心提供领导和组织结构,以协调、支持和加强 102名正式成员,53名准成员,他们是学生,博士后研究员和 研究人员和来自乌干达,南非和英国的21名国际成员组成了 CFAR。CWRU/UH CFAR利用的主要科学优势包括基于以下方面的国际研究: 我们与乌干达同事的26年合作,免疫发病机制,基础病毒学和治疗研究, 和临床试验。行政核心制定了一项深思熟虑、反应迅速的战略规划 在CFAR成员和机构领导人的投入下制定的进程。执行战略 计划包括加强和重新调整核心,利用机构资金投资于关键的新项目, 核心技术,CFAR的有效财政控制,为CFAR提供信息的外展计划 调查人员和当地社区的最新进展和事件,以及促进跨CFAR的方法 联动案例CWRU/CFAR行政核心A的具体目标是: ·协调严格的年度审查和科学的规划过程,并执行计划 通过加强核心服务,招聘和刺激新的研究活动。 ·利用机构支持,加强我们机构的艾滋病毒/艾滋病研究。 ·支持我们对乌干达艾滋病毒/艾滋病研究的长期承诺。CFAR运行 撒哈拉以南非洲最先进的科学实验室之一。 ·促进整个CFAR的培训活动。 ·改善整个CFAR的沟通,并监督生物安全活动。 ·参与国家CFAR网络内的合作研究工作。 总之,行政核心通过利用其资源, 制定并实施一个精心设计的战略计划。当意外事件发生时,由于教师 由于新的科学进步,艾滋病毒研究议程发生了变化,核心小组 这表明它能够迅速有效地作出反应。
英文摘要
Project Summary Core A – Administrative Core The CWRU/UH CFAR Administrative Core is responsible for driving the direction of the HIV/AIDS research at our institutions while at the same time responding to evolving research needs of CFAR investigators. The Administrative Core provides the leadership and organizational structure to coordinate, support and enhance the efforts of the 102 Full members, 53 Associate members, who are students, postdoctoral fellows and research associates and 21 International members from Uganda, South Africa, and Britain that make up the CFAR. Major scientific strengths leveraged by the CWRU/UH CFAR include international research based on our 26 year collaboration with colleagues in Uganda, immune pathogenesis, basic virology and Cure research, and clinical trials. The Administrative Core has developed a thoughtful and responsive Strategic Planning process developed with input from CFAR members and institutional leaders. Implementation of the Strategic Plan includes strengthening and realigning the Cores, using institutional funds to invest in key new technologies for the Cores, effective fiscal controls for the CFAR, outreach programs to inform CFAR investigators and the local community of recent progress and events, and methods to foster cross-CFAR linkages. The Specific Aims for the Case CWRU/CFAR Administrative Core A are: · To coordinate a rigorous annual review and scientific planning process and to implement the plan through enhancement of Core services, recruitment, and stimulating new research activities. · To leverage institutional support to enhance HIV/AIDS research at our institutions. · To support our long-standing commitment to HIV/AIDS research in Uganda. The CFAR operates one of the most advanced scientific laboratories in sub-Saharan Africa. · To stimulate training activities throughout the CFAR. · To improve communications throughout the CFAR and oversee Biosafety activities. · To participate in collaborative research efforts within the national CFAR network. In summary, the Administrative Core provides effective leadership for the CFAR by using its resources to generate and implement a well-conceived strategic plan. When unexpected events happen, due to Faculty recruitment or turnover, or changes in the HIV research agenda due to new scientific advances, the Core has demonstrated that it can respond in a rapid and effective fashion.
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The role of RNA m6A modification in the regulation of HIV latency and reactivation
  • 批准号:
    10600078
  • 项目类别:
  • 资助金额:
    $71.55万
  • 财政年份:
    2022
  • 负责人:
    JONATHAN KARN
  • 依托单位:
The role of RNA m6A modification in the regulation of HIV latency and reactivation
  • 批准号:
    10461499
  • 项目类别:
  • 资助金额:
    $71.55万
  • 财政年份:
    2022
  • 负责人:
    JONATHAN KARN
  • 依托单位:
Research Support Core B: Primary Cell, Biomimetic, and iPSC-derived Cell Models
  • 批准号:
    10304584
  • 项目类别:
  • 资助金额:
    $73.12万
  • 财政年份:
    2021
  • 负责人:
    JONATHAN KARN
  • 依托单位:
Research Support Core B: Primary Cell, Biomimetic, and iPSC-derived Cell Models
  • 批准号:
    10632094
  • 项目类别:
  • 资助金额:
    $73.12万
  • 财政年份:
    2021
  • 负责人:
    JONATHAN KARN
  • 依托单位:
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