Assessing Personal Exposure to Ultrafine PM Number and Respiratory Health
评估个人接触超细颗粒物的情况和呼吸系统健康
基本信息
- 批准号:9024533
- 负责人:
- 金额:$ 19.27万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2015
- 资助国家:美国
- 起止时间:2015-03-01 至 2017-02-28
- 项目状态:已结题
- 来源:
- 关键词:15 year oldActivities of Daily LivingAddressAdolescentAir PollutantsAir PollutionAsthmaBicyclingBirthCaliberChestChildChildhoodCohort StudiesCollaborationsDataData CollectionDevelopmentDevicesEnrollmentEnsureEpidemiologic StudiesEpidemiologistEpidemiologyExerciseExposure toFeedbackGenerationsGoalsHealthHome environmentHourHumanHypersensitivityLaboratoriesMeasurableMeasurementMeasuresModelingModificationNoiseParentsParticipantParticulate MatterPatternPerformancePhasePilot ProjectsPositioning AttributePreparationProcessResearchResolutionRespiratory physiologyRunningSamplingSchoolsSeasonsSmokingTechnologyTimeUltrafineWalkingWeightarmbasecohortcookingdemographicsfield studyimprovedindoor exposureland usemeetingsnovelparticleparticle exposurepulmonary functionrespiratory healthsensorspatiotemporaltooltraffickingultrafine particleusability
项目摘要
DESCRIPTION (provided by applicant): Accurately measuring personal exposure to air pollutants remains the greatest obstacle to determining their impact on human health. The need for more precise exposure assessment is particularly evident for children and adolescents whose exposure can vary widely based on their time-activity patterns including time spent outdoors, at home, school, and in vehicles. In order to meet the need of epidemiologists to characterize personal exposure, we have developed and validated in laboratory settings a novel personal sensor capable of measuring, with high spatiotemporal resolution, exposure to ultrafine particles (UFP). Results of an initial field test found the sensor to be mobile, rugged, and able t provide accurate spatiotemporal measurements of personal UFP exposure. Feedback from children participating in the initial field test indicated that barriers to its use included its voume, weight, and noise. Therefore, we now propose a two-phase project to: 1) evaluate the usability of the sensor after reducing its size, weight, and noise while maintaining its previous measurement capabilities (R21 Phase) and 2) deploy the modified sensor to characterize personal UFP exposure for adolescents enrolled in the Cincinnati Childhood Allergy and Air Pollution Study (CCAAPS) and assess the impact of short-term and peak UFP exposure on respiratory health (R33 Phase). The proposed study represents a continued collaboration between tool-developers and environmental epidemiologists and will allow for the iterative refinement of a personal sensor for UFP exposure. In addition, the application of the sensor in a large-scale epidemiologic study during the R33 phase will address a significant research question regarding the association between short-term and peak UFP exposure and respiratory health. Successful completion of the proposed project will result in a new tool for measuring personal UFP exposure in real world settings and demonstrate the value of the sensor to address novel hypotheses through improved exposure assessment.
描述(由申请人提供):准确测量个人接触空气污染物的程度仍然是确定其对人类健康影响的最大障碍。尤其需要对儿童和青少年进行更精确的暴露评估,因为儿童和青少年的暴露程度可能因其时间活动模式而有很大差异,包括在户外、家中、学校和车辆中度过的时间。为了满足流行病学家对个人暴露特征的需求,我们在实验室环境中开发并验证了一种新型个人传感器,该传感器能够以高时空分辨率测量超细颗粒(UFP)暴露。最初的现场测试结果表明,该传感器可移动,坚固耐用,能够提供个人UFP暴露的准确时空测量。参与最初现场测试的儿童反馈表明,使用它的障碍包括它的体积、重量和噪音。因此,我们现在提出了一个两阶段的项目:1)评估传感器在减小其尺寸、重量和噪音后的可用性,同时保持其先前的测量能力(R21阶段);2)部署改进的传感器来表征参加辛辛那提儿童过敏和空气污染研究(CCAAPS)的青少年的个人UFP暴露,并评估短期和峰值UFP暴露对呼吸健康的影响(R33阶段)。拟议的研究代表了工具开发人员和环境流行病学家之间的持续合作,并将允许迭代改进UFP暴露的个人传感器。此外,该传感器在R33阶段的大规模流行病学研究中的应用将解决一个重要的研究问题,即短期和峰值UFP暴露与呼吸健康之间的关系。该项目的成功完成将产生一种新的工具,用于测量现实世界中个人UFP暴露,并通过改进暴露评估来证明传感器在解决新假设方面的价值。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Patrick H Ryan其他文献
Patrick H Ryan的其他文献
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{{ truncateString('Patrick H Ryan', 18)}}的其他基金
Developing and Evaluating Novel Strategies for Reporting Back Individual Results of Personal Air Monitors
开发和评估报告个人空气监测器个人结果的新策略
- 批准号:
10019550 - 财政年份:2019
- 资助金额:
$ 19.27万 - 项目类别:
Neurobehavioral and Neuroimaging Effects of Traffic Exposure in Children
交通暴露对儿童的神经行为和神经影像学影响
- 批准号:
8295885 - 财政年份:2012
- 资助金额:
$ 19.27万 - 项目类别:
Neurobehavioral and Neuroimaging Effects of Traffic Exposure in Children
交通暴露对儿童的神经行为和神经影像学影响
- 批准号:
8651760 - 财政年份:2012
- 资助金额:
$ 19.27万 - 项目类别:
Neurobehavioral and Neuroimaging Effects of Traffic Exposure in Children
交通暴露对儿童的神经行为和神经影像学影响
- 批准号:
9042361 - 财政年份:2012
- 资助金额:
$ 19.27万 - 项目类别:
Neurobehavioral and Neuroimaging Effects of Traffic Exposure in Children
交通暴露对儿童的神经行为和神经影像学影响
- 批准号:
8500278 - 财政年份:2012
- 资助金额:
$ 19.27万 - 项目类别:
Field Validation of a Personal Sensor for Ultrafine PM in Asthmatic Children
哮喘儿童超细颗粒物个人传感器的现场验证
- 批准号:
8333964 - 财政年份:2011
- 资助金额:
$ 19.27万 - 项目类别:
Field Validation of a Personal Sensor for Ultrafine PM in Asthmatic Children
哮喘儿童超细颗粒物个人传感器的现场验证
- 批准号:
8177520 - 财政年份:2011
- 资助金额:
$ 19.27万 - 项目类别:
Field Validation of a Personal Sensor for Ultrafine PM in Asthmatic Children
哮喘儿童超细颗粒物个人传感器的现场验证
- 批准号:
8503653 - 财政年份:2011
- 资助金额:
$ 19.27万 - 项目类别:
Impact of Traffic-Related Particles on Asthma for Students in an Urban School Dis
城市学校交通相关颗粒物对学生哮喘的影响
- 批准号:
8459667 - 财政年份:2009
- 资助金额:
$ 19.27万 - 项目类别:
Impact of Traffic-Related Particles on Asthma for Students in an Urban School Dis
城市学校交通相关颗粒物对学生哮喘的影响
- 批准号:
8118289 - 财政年份:2009
- 资助金额:
$ 19.27万 - 项目类别:
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