Sustained Training in Aging and HIV Research (STAHR)

老龄化和艾滋病毒研究持续培训（STAHR）

• 批准号: 9140529
• 负责人: DILIP V. JESTE
• 金额: $ 24.62万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-04-01 至 2021-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9140529
• 关键词: Acquired Immunodeficiency Syndrome; Address; Adult; Age; Aging; Area; Bioinformatics; Biological Markers; Biology of Aging; Biometry; California; Cessation of life; Chronic Disease; Clinical; Cognitive aging; Collaborations; Communities; Community Developments; Comorbidity; Complex; Country; Development; Development Plans; Disease Management; Distance Learning; Educational workshop; Elderly; Engineering; Ethics; Evaluation; Faculty; Family Practice; Fostering; Functional disorder; Funding; Funding Mechanisms; Geriatric Psychiatry; HIV; Highly Active Antiretroviral Therapy; Home environment; Immunology; Impaired cognition; Individual; Institutes; Institution; Intervention; Knowledge; Life; Manuscripts; Medicine; Mental Health; Mental disorders; Mentors; Mentorship; Morbidity - disease rate; National Institute of Mental Health; Neuronal Plasticity; Neurosciences; Neurosciences Research; Outcome Measure; Personal Satisfaction; Pharmacy Schools; Polypharmacy; Postdoctoral Fellow; Preventive Medicine; Process; Psychiatry; Publications; Research; Research Activity; Research Infrastructure; Research Institute; Research Personnel; Research Project Grants; Research Support; Research Training; Resources; Rosa; Schools; Science; Scientist; Seeds; Sum; Training; Training Programs; Universities; Work; career; career development; cohort; cultural competence; design; experience; improved; innovation; interest; medical schools; multidisciplinary; neuroAIDS; neurobehavioral; neurocognitive disorder; neuropsychiatry; novel strategies; prevent; programs; psychosocial; public health relevance; resilience; skills; stressor; success; summer institute; summer research

 DESCRIPTION (provided by applicant): This application aims to develop, implement, and evaluate an innovative research training program designed to expand the number of NIMH-funded new investigators conducting mental health research at the intersection of HIV and aging. Over half of HIV-infected adults in the US are over age 50, and this number is expected to rise. The coexistence of HIV and aging in the context of mental health encompasses a complex relationship with issues of physical and psychiatric comorbidity, polypharmacy, cognitive impairment, and psychosocial stressors on one hand, and positive aspects such as successful aging, resilience, and neuroplasticity on the other. Yet, there is much to be known about pathophysiology, biomarkers, and interventions for enhancing mental health as well as for treating and preventing mental illnesses, including neurocognitive disorders, in older adults with HIV. Fostering the development of researchers with knowledge and expertise in both aging and HIV will be critical for the promotion of urgently needed research in this field. The proposed Sustained Training in Aging and HIV Research (STAHR) program builds on the infrastructure and expertise available at two major research programs at the University of California, San Diego (UCSD): the Sam and Rose Stein Institute for Research on Aging and the HIV Neurobehavioral Research Program. It seeks to address several strategic objectives of the NIMH Division of AIDS Research and the Office of AIDS Research. It will involve faculty from different departments in the UCSD School of Medicine as well as the Schools of Pharmacy and Engineering, along with mentors from other institutions. The program will target clinical and translational post- doctoral fellows and junior faculty from across the country, with previous training in either aging or HIV research, but interested in gaining expertise in the intersection o these two factors. Four new scholars will be selected every year; each will have a primary mentor at her/his home institution and a co-mentor at UCSD. These scholars will attend a 4-week summer institute during their first year and an annual 3-day workshop at UCSD for 3 years. A secondary aim of STAHR is to establish a network of mentors with interest in HIV and aging research to serve as a standing resource for the trainees. Training will aim to increase knowledge and skills on HIV/Aging research, and will also include training in research process and career development. There will be an Individual Development Plan for each scholar, which will outline mentoring activities and research experiences. Innovative distance learning opportunities will be offered in topics such as team science, funding mechanisms, mentorship training, and cultural competence. Other features include active involvement of community stakeholders, group projects, sessions on mentoring, and wide dissemination of STAHR results. There will be rigorous short and long-term evaluation of the scholars' career progress. STAHR will aim to develop high quality independently-funded investigators, who will make lasting contributions to mental health research in HIV/Aging, and sow the seeds for developing a new sub-field of Geriatric HIV Neuropsychiatry.

 描述（由应用程序提供）：本应用程序旨在开发，实施和评估一项创新的研究培训计划，旨在扩大NIMH资助的新调查人员的数量，该研究人员在艾滋病毒和衰老的交集中进行心理健康研究。在美国，超过一半的艾滋病毒感染成年人超过50岁，预计这一数字将增加。在心理健康背景下，艾滋病毒和衰老的共存涵盖了与身体和精神病合并症，一方面的多药，认知障碍以及心理压力源的复杂关系，以及成功的衰老，复原力和神经性质感等积极方面。然而，在患有艾滋病毒的老年人中，关于增强心理健康以及治疗和预防精神疾病（包括神经认知障碍）的病理生理学，生物标志物和干预措施，还有很多了解。促进具有衰老和艾滋病毒知识和专业知识的研究人员的发展对于促进该领域急需的研究至关重要。拟议的持续培训在衰老和艾滋病毒研究计划（Stahr）计划基于加利福尼亚大学圣地亚哥分校（UCSD）的两个主要研究计划的基础设施和专业知识：Sam和Rose Stein衰老研究所和HIV Neiv Neurobehavioral Havioral研究计划。它试图解决艾滋病研究部和艾滋病研究办公室的几个战略对象。它将涉及来自UCSD医学院不同部门的教职员工以及药房和工程学学校，以及其他机构的导师。该计划将针对来自全国各地的临床和翻译博士后研究员和初级教师，并先前接受了衰老或艾滋病毒研究的培训，但有兴趣在这两个因素的交集中获得专业知识。每年将选出四个新学者；每个人都将在她/他的家庭机构中有一位主要导师，并在UCSD拥有一位院长。这些学者将在他们的第一年参加为期4周的夏季学院，并在UCSD举行的每年3天的研讨会3年。 Stahr的次要目的是建立一个对艾滋病毒和衰老研究感兴趣的导师网络，以作为学员的常规资源。培训将旨在提高艾滋病毒/衰老研究的知识和技能，还包括研究过程和职业发展方面的培训。每个学者将制定一个个人发展计划，该计划将概述指导活动和研究经验。创新的远程学习机会将在团队科学，资助机制，指导培训和文化能力等主题中提供。其他功能包括积极参与社区利益相关者，小组项目，心理化会议以及广泛的Stahr结果传播。将对学者的职业进步进行严格的短期评估。 Stahr将旨在发展高质量的独立研究人员，他们将为艾滋病毒/衰老的心理健康研究做出持久的贡献，并播种种子，以开发新的老年艾滋病毒神经精神病学子场。