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Yoga as a Complementary Therapy for Type 2 Diabetes: An Initial Investigation

瑜伽作为 2 型糖尿病的补充疗法：初步调查

基本信息

批准号：
9114071
负责人：
Beth C Bock
金额：
$ 18.27万
依托单位：
MIRIAM HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-08-01 至 2018-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9114071
关键词：
Accounting Adult Aerobic Exercise Affect American Anxiety Attention Behavior Behavior Therapy Behavioral Belief Biological Markers Blood Glucose Body Composition Body mass index Breathing Chronic Disease Clinical Trials Complementary therapies Complications of Diabetes Mellitus Country Data Diabetes Mellitus Diagnosis Diet Elderly Exercise Eye Fasting Feasibility Studies Focus Groups Future Glucose Glycosylated hemoglobin A Goals Health Health behavior Healthcare Systems Home environment Hydrocortisone Intervention Investigation Jogging Kidney Lead Measures Mediator of activation protein Meditation Methodology Modeling Nerve Non-Insulin-Dependent Diabetes Mellitus Outcome Participant Patients Perception Pharmaceutical Preparations Physical Fitness Physical activity Plasma Population Protocols documentation Psychological Stress Randomized Randomized Controlled Trials Relaxation Role Salivary Self Care Self Efficacy Stress Stroke Testing Time Training Walking Yoga base cardiovascular disorder risk design diabetes management diabetic diet and exercise exercise adherence glycemic control heart disease risk improved mindfulness prevent programs psychologic randomized trial retention rate satisfaction secondary outcome sedentary stress management stress resilience waist circumference walking program

项目摘要

DESCRIPTION (provided by applicant): Diabetes affects nearly 29 million Americans and another 86 million adults in the U.S. are prediabetic. Type 2 diabetes (T2DM) accounts for 90-95 percent of all diabetes cases in adults. Uncontrolled diabetes, over time, can cause serious damage to kidneys, eyes, and nerves and increases the risk of heart disease and stroke. Controlling blood glucose level is crucial to avoid these serious complications. Traditional aerobic exercise (e.g., walking, jogging, cycling) is known to improve blood glucose levels in patients with T2DM. Yoga, an ancient eastern practice, shares many of the same benefits as exercise. Like aerobic exercise, yoga practice can elicit improvements in health related aspects of physical fitness. Yoga is also a mindfulness practice with emphasis on relaxation, meditation, and deep breathing, and therefore may have special relevance to people with T2DM. Yoga by increasing mindfulness and parasympathetic activity can alleviate stress. Randomized trials with healthy and diseased participants have shown the benefit of yoga on stress reduction. By inducing stress resilience, yoga may prevent stress-induced rise in cortisol, thus controlling rise in blood glucose levels. Moreover, by reducing stress, and increasing mindfulness, yoga may also lead to improved self-care behaviors including improved diet and physical activity. The role of yoga as a complementary therapy for diabetics within the socio-cultural context of the U.S. needs additional examination. The purpose of the current application is to test a yoga intervention for adults with T2DM and to gather data on the feasibility and acceptability of yoga compared to a Wellness Contact Control for glycemic control. We will conduct a pilot randomized controlled study with participants randomly assigned to 1) Yoga intervention, or 2) Wellness Contact Control. Focus groups will be conducted with participants at the end of the intervention to identify facilitators and barriers to yoga practice and to examine their perception and beliefs about yoga and its relationship to stress and diabetes management. We will measure HbA1c levels, fasting and postprandial plasma glucose at baseline, end of treatment (12-weeks), 6- and 9-month follow-ups. We will also explore the effect of yoga on stress (biomarker salivary cortisol) that may act as mechanisms of action underlying the efficacy of yoga for improved glycemic control. Study feasibility and acceptability will be assessed using participant recruitment, attendance and retention rates, and compliance with study protocols and general satisfaction with the program. Results from this study will provide scientific basis fo a future larger clinical trial. Yoga, if found to offer advantages for glycemic control, can have potential for high impact on current practices of diabetes management.