Diversity Action Plan for Mouse Genome Database

 描述（由申请人提供）：缅因州巴尔港的杰克逊实验室（JAX）提出了一个夏季研究实习，每年有四名学生来自代表性不足的群体，在NHGRI资助的小鼠基因组数据库（MGD）的研究人员的指导下，从事生物信息学和基因组学的研究项目。拟议的多样性行动计划（DAP）寻求资金，以继续这一成功的计划四年多，与鼓励代表性不足的学生追求先进的学位和职业生涯在基因组学相关领域的目标。MGD被认为是国际科学界的小鼠数据库，提供高质量的综合信息，支持小鼠实验系统转化为人类生物学和疾病研究。 四名MGD DAP生物信息学实习生将被整合到现有的JAX暑期学生计划（SSP）中，这是一项国际公认的住宅研究经验，自1924年以来已指导了2，100多名本科生和高中生。这个既定的JAX计划每年举办30- 40名学生谁是通过竞争激烈的全国性申请过程中选择。每个学生每周都会获得津贴，生活津贴和旅行援助，使他们能够放弃暑期工作并参与这种身临其境的转型研究体验。除了在动手计算和实验室工作，提案写作和结果演示，并在研究道德和实验室动物的人道待遇坚实的基础培训，所有SSP参与者一起住在一个40间客房的住宅，并分享丰富的社交和娱乐活动。JAX SSP--由机构基金、私人基金会和联邦赠款支持--在多样性招聘和选择、导师指导以及项目设计、管理和评估方面有完善的行政程序。拟议DAP的培训协调员将从事生物信息学特定的多样性招聘，支持实习生培训，并在其随后的职业发展中跟踪计划校友。DAP首席研究员将监督所有DAP计划和实施，包括导师指导和项目管理。JAX提供了一个激励人心的环境，来自不同背景的有动力，有才华的本科生可以学习科学探究的基础知识，为研究进展做出贡献，并在智力和个人成长方面取得长足进步，这将指导他们的职业选择和终身学习。 SSP拥有代表性不足的少数民族（西班牙裔，非洲裔美国人，美洲土著人，太平洋岛民/夏威夷人）参与的良好记录，这是通过全国范围内有针对性的招聘，SSP网站和校友网络实现的。2014年暑期学生计划有11名代表性不足的少数民族学生（29%），其中包括7名参与者（18%）谁是第一代大学生或经济上处于不利地位。 与公共卫生的关系：拟议的生物信息学和基因组学暑期实习将为学生提供机会，为杰克逊实验室由NHGRI资助的小鼠基因组数据库（MGD）项目的研究人员提供指导，为积极的研究项目做出贡献。MGD数据库专门设计用于促进小鼠作为模型系统的使用，以在基因组规模，数据驱动的生物医学研究时代实现有关人类健康和疾病的新发现。我们专注于从代表性不足的群体中招募学生，以确保未来科学，医学和教育劳动力的多样性。来自这种沉浸式研究体验的校友将成为科学大使，具有坚实的道德基础，对数据科学的挑战和承诺表示赞赏，以推进基本的人类疾病研究，并热衷于分享他们对科学的热爱，以造福社会。

 DESCRIPTION (provided by applicant): The Jackson Laboratory (JAX) in Bar Harbor, Maine, proposes a summer research internship for four students per year from underrepresented groups to pursue research projects in bioinformatics and genomics, under the mentorship of investigators of the NHGRI-funded Mouse Genome Database (MGD). The proposed Diversity Action Plan (DAP) seeks funding to continue this successful program for four more years, with a goal of encouraging underrepresented students to pursue advanced degrees and careers in genomics-related fields. MGD is regarded as the international scientific community database for mouse, providing high quality, integrated information that supports the translation of the mouse experimental system to the study of human biology and disease. The four MGD DAP bioinformatics interns will be integrated into the existing JAX Summer Student Program (SSP), an internationally recognized residential research experience that has mentored more than 2,100 undergraduates and high school students since 1924. This established JAX program annually hosts 30- 40 students who are selected through a competitive nationwide application process. Each student receives a weekly stipend, subsistence allotment, and travel assistance that enables them to forgo summer jobs and participate in this immersive, transformational research experience. In addition to training in hands-on computational and laboratory work, proposal writing and results presentation, and solid grounding in research ethics and the humane treatment of lab animals, all SSP participants lodge together in a 40-room residence and share abundant social and recreational activities. The JAX SSP--supported by institutional funds, private foundations, and federal grants--has well-established administrative procedures for diversity recruitment and selection, mentor guidance, and program design, management, and evaluation. The Training Coordinator for the proposed DAP will pursue bioinformatics-specific diversity recruitment, support intern training, and track program alumni during their subsequent career development. The DAP Principal Investigator will oversee all DAP planning and implementation, including mentor guidance and program administration. JAX offers a stimulating environment in which motivated, talented undergraduates from diverse backgrounds can learn the fundamentals of scientific inquiry, contribute to research progress, and make great strides in intellectual and personal growth that will guide them in career choices and lifelong learning. The SSP has a proven track record of underrepresented minority (Hispanic, African American, Native American, Pacific Islander/Hawaiian) participation, which is achieved through targeted recruiting nationwide, the SSP website, and alumni networking. The 2014 Summer Student Program had 11 underrepresented minority students (29%), including 7 participants (18%) who were first-generation college students or were economically disadvantaged. PUBLIC HEALTH RELEVANC: The proposed summer internship in bioinformatics and genomics will offer students the opportunity to contribute to active research projects with mentorship from the investigators in the NHGRI-funded Mouse Genome Database (MGD) program at The Jackson Laboratory. The MGD database is designed specifically to facilitate use of the mouse as a model system to enable new discoveries about human health and disease in the age of genome-scale, data-driven biomedical research. We focus on recruiting students from underrepresented groups to ensure diversity in the scientific, medical, and education workforces of the future. The alumni from this immersive research experience will be science ambassadors with a solid grounding in ethics, an appreciation for the challenges and promises of data science for advancing basic human disease research, and zeal to share their love of science for the benefit of society.