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中文摘要
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 描述(由申请人提供):这项提案是为了部分支持将于2016年7月10日至15日在马萨诸塞州南哈德利的芒特霍利奥克学院举行的离子通道国际会议,这是戈登研究会议系列的一部分。这次会议的长期目标是增加对离子通道的基本结构、功能和生理作用的理解,以及这些功能在人类疾病中是如何被破坏的。本次会议的具体目的将是召集代表离子通道研究关键领域的40名演讲者和讨论负责人与160名普通与会者一起,在相对隐蔽的环境中举行为期五天的会议,最多200名与会者。该计划将包括九个环节,受邀的演讲者和从参与者中挑选出来的演讲者将展示他们最新的、未发表的研究成果,并有充足的时间讨论结果。此外,四个海报会议将允许所有参与者展示他们自己的作品。这次会议的意义在于,多年来,它一直是对离子通道结构和功能的基本机制感兴趣的科学家们的首要会议。离子通道GRC所产生的小规模和密集的讨论使其对于催化新的想法、方向和参与者之间的合作具有独特的重要性。离子通道在确定膜的电兴奋性方面起着关键作用,它们的功能障碍是从先天性听力损失到癫痫和心脏病等多种疾病的基础。因此,通过本次会议传播的信息有可能对人类健康的所有领域产生广泛的影响。
英文摘要
 DESCRIPTION (provided by applicant): This proposal is for partial support for an international meeting on Ion Channels, as part of the Gordon Research Conference series, to be held at Mount Holyoke College in South Hadley, Massachusetts, July 10 - 15, 2016. The long-term goal of this conference is to increase understanding of the fundamental structure, function and physiological roles of ion channels and how these functions are disrupted in human disease. The specific aim of this meeting will be to convene 40 speakers and discussion leaders who represent critical areas of ion channel research together with 160 participants-at-large for a maximum of 200 participants for a five-day meeting in a relatively secluded setting. The program will consist of nine sessions in which invited speakers and speakers chosen from the participants-at-large will present their latest, unpublished, research, with ample time for discussion of the results. In addition, four poster sessions will permit all participants to presen their own work. The significance of this meeting is that is has been for many years, and remains, the premier meeting for scientists interested in fundamental mechanisms of ion channel structure and function. The small size and intensive discussions engendered by the Ion Channels GRC make it uniquely important for the catalysis of new ideas, directions and collaboration among the participants. Ion channels play a critical role in establishing the electrical excitability of membranes and their dysfunction underlies a large variety of disorders, from congenital hearing loss, to epilepsy and heart disease. Thus information disseminated through this meeting has the potential to be of wide relevance to all areas of human health.
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