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中文摘要
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摘要 西弗吉尼亚州儿科临床试验网络(WVPCTN)将作为IDEA州的临床中心 PCTN为西弗吉尼亚州阿巴拉契亚州中部农村的个人提供临床试验, 周边县纳入直属服务区。WVPCTN将作为一个关键的准备, 一个临床中心的基础上的历史,身体,心理社会和财政负担所带来的众多 慢性疾病状况以及导致这些状况的各种环境风险因素 在西弗吉尼亚州WVPCTN作为一个成功的临床中心,由于以下因素的结合, 各种结构和人力资源已经到位,以解决:主题识别,主题 招募和研究表现。具体而言,WVPCTN将利用以下内容: - 西弗吉尼亚大学CTSI的综合数据库(包含超过200万份患者记录),大型新生儿和 来自我们的出生分数和心脏项目的学龄队列(在研究计划中详细描述),以及 来自西弗吉尼亚州围产期伙伴关系网络的目标人群, 和职业和环境研究的西弗吉尼亚大学系;为主题招聘-西弗吉尼亚大学一般 和专科诊所,我们的CTSI赞助的基于实践的研究网络,我们的牙科基础设施, COHRA赠款,出生分数和心脏的基础设施,以及各种专门的现有设置; 对于研究绩效-经验丰富的研究者人才库、一群学员研究者和资源 和监督西弗吉尼亚大学CTSI赞助的临床试验研究中心的核心。这些特点和资源, 与全国各地强大和持续的伙伴关系,以及与环境有关的多个 我们的公民的条件,独特的地位,我们都是成功的PCTN试验,并提出新的试验, PCTN。WVPCTN将增加对全州儿科重点举措的长期承诺 并受益于已建立的全州网络,部分是通过积极的IDEA国家机制。 因此,我们处于独特的地位,可以充分利用额外的资金,有效地建立基础设施, 提供尖端试验的机会,这将影响西弗吉尼亚州儿童的健康。
英文摘要
Abstract The West Virginia Pediatric Clinical Trials Network (WVPCTN) will work as a Clinical Center of the IDeA States PCTN to provide clinical trial access to individuals in the rural, central Appalachian state of West Virginia and surrounding counties included in the immediate service area. The WVPCTN will be critically poised to serve as a Clinical Center based on the historical, physical, psychosocial, and fiscal burdens brought about by a multitude of chronic disease conditions and a wide variety of environmental risk factors that contribute to those conditions in West Virginia. The WVPCTN is well positioned to be successful as a Clinical Center due to a combination of a variety of structural and human resources already in place that address: Subject Identification, Subject Recruitment and Study Performance. Specifically, the WVPCTN will utilize the following: for Subject Identification - the Integrated Data Repository of the WVU CTSI (containing over 2 million patient records), large neonatal and school age cohorts from our Birth Score and CARDIAC projects (described in detail in the Research Plan), and targeted cohorts from the West Virginia Perinatal Partnership Network, the Center of Excellence in Disabilities and the WVU Department of Occupational and Environmental Studies; for Subject Recruitment – WVU General and Specialty Clinics, our CTSI sponsored Practice Based Research Network, the infrastructure of our Dental COHRA grant, the infrastructure from Birth Score and CARDIAC, and a variety of specialized existing settings; for Study Performance – an experienced investigator pool, a group of mentee investigators, and the resources and oversight of the WVU CTSI sponsored Clinical Trials Research Unit core. These features and resources, together with strong and sustained partnerships throughout the state, and the multiple environmentally related conditions of our citizens, uniquely position us to both be successful at PCTN trials and propose new trials for the PCTN. The WVPCTN will add to a long standing commitment to pediatric focused initiatives across the state and benefit from statewide networks that have been established, in part through active IDeA State mechanisms. As such, we are uniquely positioned to fully leverage additional funds to efficiently establish the infrastructure to provide access to cutting edge trials which will impact the health of the children of West Virginia.
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FOYC+ImPACT US: A digital platform for critical sexual health risk reduction curriculum customization and hybrid/remote delivery of Focus on Youth to underserved Caribbean youth in the U.S.
  • 批准号:
    10699553
  • 项目类别:
  • 资助金额:
    $27.55万
  • 财政年份:
    2023
  • 负责人:
    LESLEY A COTTRELL
  • 依托单位:
West Virginia Pediatric Clinical Trials Network-2
  • 批准号:
    10064509
  • 项目类别:
  • 资助金额:
    $41.79万
  • 财政年份:
    2020
  • 负责人:
    LESLEY A COTTRELL
  • 依托单位:
West Virginia Pediatric Clinical Trials Network-2
  • 批准号:
    10470164
  • 项目类别:
  • 资助金额:
    $41.77万
  • 财政年份:
    2020
  • 负责人:
    LESLEY A COTTRELL
  • 依托单位:
West Virginia Pediatric Clinical Trials Network-2
  • 批准号:
    10239228
  • 项目类别:
  • 资助金额:
    $41.77万
  • 财政年份:
    2020
  • 负责人:
    LESLEY A COTTRELL
  • 依托单位:
海外基金