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West Virginia Pediatric Clinical Trials Network-2

西弗吉尼亚州儿科临床试验 Network-2

基本信息

批准号：
10239228
负责人：
LESLEY A COTTRELL
金额：
$ 41.77万
依托单位：
WEST VIRGINIA UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-09-01 至 2025-08-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10239228
关键词：
Acceleration Acute Address Appalachian Region Behavior Therapy Characteristics Child Child Health Childhood Chronic Chronic Disease Clinical Clinical Research Clinical Sciences Clinical Trials Clinical Trials Network Collaborations Disease Economics Effectiveness Environmental Risk Factor Faculty Fostering Funding Goals Health Human Resources Hypertension Infant Infrastructure Institutes Intervention Investigation Lead Leadership Mentors Methods Mission Multicenter Trials Neonatal Abstinence Syndrome Outcome Pediatric Research Performance Positioning Attribute Prevention Research Research Infrastructure Research Personnel Resources Rural Population Site Standardization Structure Teacher Professional Development Training Translational Research Underserved Population Ursidae Family West Virginia Work catalyst clinical research site experience follow-up in utero insight interest neonate opioid epidemic opioid exposure psychosocial recruit rurality skills success tool trend

项目摘要

Abstract West Virginia (WV) bears long-standing physical, psychosocial and fiscal characteristics, including the opioid crisis, limited resources and a restricted economy, that have significantly impacted the health of its residents. The West Virginia Pediatric Clinical Trials Network (WVPCTN), as a Clinical Site of the ECHO IDeA States PCTN (ISPCTN), has catalyzed emerging solutions to address some of these burdens by fulfilling its mission. Specifically, the mission of the WVPCTN has been two-fold - bringing clinical trials to our underserved population, and building professional capacity for clinical research. Our WVU site has been well positioned to be a successful Clinical Site due to a combination of structural and human resources that were already in place when the ISPCTN was initiated in 2016, and the background and expertise of the three PIs – Drs. Saul, Pyles and Cottrell. The addition of the funds and resources provided by ISPCTN led to an acceleration of WVUs capacity to actively participate in clinical trials by allowing us to create a dedicated Pediatric Research Unit (PRU) and introduce a group of junior, less experienced clinical trial investigators, into both ISPCTN and non-ISPCTN trials. The effectiveness of this approach has been demonstrated through an increase in faculty participation in ISPCTN activities, a strong recruitment record, and an increase in the number of non-ISPCTN Pediatric trials at WVU. The WVPCTN is now actively growing an experienced investigator pool and a group of mentee investigators, all enhanced by the resources and expertise of the West Virginia Clinical Translational Science Institute (WVCTSI). These features and resources, together with strong and sustained partnerships throughout the state, and the multiple environmentally related conditions of our citizens, continue to uniquely position us to be successful as an ISPCTN Clinical Site and work to propose new trials for the network. This proposal for WVPCTN-2 will further add to a long-standing commitment to Pediatric-focused initiatives across the state. When funded, it will continue to position us to fully leverage additional funds that support Pediatric research infrastructure and provide access to cutting edge trials, both of which will positively impact the health of the children of WV.

摘要