BIOINFORMATICS CORE

缅因州IDEA生物医学研究卓越网络(ME-INBRE)生物信息学核心将支持 通过提供必要的数据咨询和培训，开展比较功能基因组学研究 管理、生物信息学和统计分析。生物医学研究越来越多地利用高通量 技术，核心将为教师和他们的学生提供专门的专业知识 管理、分析和解释来自大型数据集的结果。经验丰富的核心员工将提供 咨询服务，以及获得分析工具和计算基础设施，以支持 分析工作流。分析工具包括由核心员工开发的创新miRMiner工具，用于分析 已知和新颖的microRNAs。生物信息学核心将利用区域合作和 通过ME-INBRE共同创建的东北赛本基础设施联盟(NECC)提供网络基础设施 与其他四个想法国家扩大区域网络基础设施并开展协作 研究。通过东北生物信息学合作(NEBC)，核心将与 INBRE生物信息学公司在特拉华州、新罕布夏州、罗德岛州和佛蒙特州的核心员工提供咨询 支持缅因州教职员工的项目，并合作向教职员工和学生提供生物信息学培训。 区域网络基础设施将用于密集计算和集中数据存储、共享 还有后援。将在缅因州和该地区举办一系列生物信息学研讨会 通过NEBC为ME-INBRE研究人员、研究培训学院和 学生，以及缅因州的其他教职员工和学生。核心还将主办新的生物信息学 学者计划为MEINBRE的学生提供个人指导的生物信息学研究项目 机构。总而言之，核心将在以下方面提供智力和技术专门知识和培训 ME-INBRE研究人员和研究培训人员需要完成他们的生物信息学 研究目标。

The Maine IDeA Network for Biomedical Research Excellence (ME-INBRE) Bioinformatics Core will support research in comparative functional genomics by providing essential consulting and training in data management, bioinformatic and statistical analysis. Biomedical research increasingly utilizes highthroughput technologies, and the Core will provide specialized expertise to faculty and their students for managing, analyzing and interpreting results from large data sets. Highly experienced Core staff will provide consultation services, as well as access to analysis tools and computational infrastructure, to support analysis workflows. Analysis tools include the innovative miRMiner tool developed by Core staff to analyze known and novel microRNAs. The Bioinformatics Core will leverage regional collaborations and cyberinfrastructure through the Northeast Cybennfrastructure Consortium (NECC) that ME-INBRE cofounded with four other IDeA states to expand regional cyberinfrastructure and conduct collaborative cyberenabled research. Through the Northeast Bioinformatics Collaborative (NEBC), the Core will work with INBRE Bioinformatics Core staff in Delaware, New Hampshire, Rhode Island, and Vermont on consulting projects to support Maine faculty and collaborate on delivering bioinformatics training to faculty and students. Regional cyberinfrastructure will be used for intensive computations and centralized data storage, sharing and backup. A series of bioinformatics workshops will be given both within Maine and also regionally through the NEBC to provide research training to ME-INBRE Investigators, Research Training Faculty, and students, along with other Maine faculty and students. The Core will also host the new Bioinformatics Scholars Program to provide individually mentored bioinformatics research projects for students at MEINBRE institutions. In summary, the Core will provide the intellectual and technical expertise and training in bioinformatics that ME-INBRE Investigators and Research Training Faculty need to accomplish their research goals.