Child Health Research Center

描述（由申请人提供）：这是一个新的应用程序（RFA-HD-13-011）的儿童健康研究中心在华盛顿大学医学院的支持。儿科医生-科学家在促进儿童健康相关知识方面发挥着至关重要的作用。有一个国家需要通过加强年轻的儿科医生，科学家的培训，以刺激儿童健康研究。该计划通过优化利用华盛顿大学医学院的资源，支持年轻儿科医生科学家的职业发展，就像我们过去16年所做的那样。我们中心的长期目标是培养人类发育生物学的学者。我们将通过应用基础科学（发育生物学、细胞生物学、免疫学、基因组学等）的最新进展来实现这一目标。了解儿科竞技场内广泛疾病的发病机制。为了实现这一目标，我们将联合收割机结合华盛顿大学医学院和儿科的现有研究力量。我们的学者计划，现在十六岁，最终将缩小基础科学家和儿科临床医生之间的差距。我们有一个程序结构，其中明亮，积极，年轻的儿科科学家在受保护的环境中蓬勃发展，由杰出的导师和机构文化和组织支持，优化他们作为儿科领域不断发展的领导者的出现。Alan L.施瓦茨博士，M.D.将担任私家侦探/P.D.和罗伯特·赫克鲁斯医学博士博士将担任培训主任。该中心（通过该奖项和来自华盛顿大学医学院的配套资金）及其学者将继续利用我们的机构资助的核心设施，通过新的和不断发展的最先进的技术，产生人类疾病状态的动物模型。该中心的长期目标将实现其学者在未来二十年或更长的时间内为人类发育生物学的发展和领导做出贡献。

DESCRIPTION (provided by applicant): This is a new application (RFA-HD-13-011) for support of the Child Health Research Center at Washington University School of Medicine. Pediatric physician-scientists play a vital role in advancing knowledge related to child health. There is a national need to stimulate child health research by enhancing the training of young pediatric physician-scientists. This program supports the mentored career development of young pediatric physician-scientists by optimally utilizing the resources of the Washington University School of Medicine as we have done for the past 16 years. The long term goal of our Center is to develop Scholars in human developmental biology. We shall achieve this goal by applying the recent advances in basic sciences (developmental biology, cell biology, immunology, genomics, etc.) to an understanding of the pathogenesis of a broad spectrum of diseases within the Pediatric arena. In order to accomplish this, we shall combine the established areas of investigative strength of Washington University School of Medicine and the Department of Pediatrics. Our Scholar's Program, now sixteen years old, will ultimately close the gap between basic scientists and pediatric clinicians. We have in place a programmatic structure in which bright, motivated, young pediatric scientists flourish in a protected environment supported by exceptional mentors and an institutional culture and organization which optimizes their emergence as leaders in an evolving area of Pediatrics. Alan L. Schwartz, Ph.D., M.D. will serve as P.I. /P.D. and Robert Heuckeroth, M.D., Ph.D. will serve as Training Director. The Center (via this award and matched funds from Washington University School of Medicine) and its Scholars will continue to utilize our institutionally-funded core facilities for generation of animal models of human disease states via new and evolving state-of-the-art technologies. The long term goals of the Center will be realized as its Scholars contribute to the development of and leadership in human developmental biology during the next two or more decades.