Understanding tobacco flavor effects on waterpipe smokers’ experiences and exposures
Understanding tobacco flavor effects on waterpipe smokers’ experiences and exposures
批准号:
9185394
负责人:
Wasim Maziak
金额:
$42.09万
依托单位国家:
美国
项目类别:
财政年份:
2016
资助国家:
美国
项目状态:
已结题
起止时间:
2016-08-15 至 2019-06-30
关键词:
AddressAffectAgeBehaviorBeliefCarbon MonoxideCardiovascular DiseasesCigaretteClinicalDependenceDiseaseEffectivenessEvaluationExposure toFlavoringFloridaFrequenciesHigh School StudentIndividualInternationalLaboratoriesLeadMalignant NeoplasmsMeasurementMethodsMinnesotaNicotineNicotine DependenceNicotine WithdrawalOutcomeParticipantPerceptionPlasmaPrevalenceQuestionnairesRecruitment ActivityRegulationRouteSensoryShapesSmell PerceptionSmokeSmokerSmokingSmoking BehaviorStagingStudentsStudy SubjectSurveysSymptomsTaste PerceptionTimeTobaccoTobacco smokeTobacco smokingTobacco useToxicant exposureUnited StatesUnited States Food and Drug AdministrationUniversitiesVariantYouthabstractingadverse pregnancy outcomeauthoritybasecigarette smokingevidence baseexperiencehookahnon-smokingnovelresponsesatisfactionstatisticstoxicanttrenduniversity studentuptake
中文摘要
了解烟草风味对水烟吸烟者经历和暴露的影响
英文摘要
Understanding tobacco flavor effects on waterpipe smokers' experiences and exposures
Abstract:
Waterpipe (WP) tobacco smoking (a.k.a. hookah, shisha, narghile) is increasing rapidly in the
United States (US), particularly among young people. Time trends of WP smoking among youth
in the US, show that WP smoking has become comparable to cigarette smoking among high-
school students for the first time ever in 2014. Evidence suggests that WP smoking can lead to
dependence, other tobacco use, and many of the known smoking-related diseases including
cancer, cardiovascular disease and adverse pregnancy outcomes. These alarming trends led the
Food and Drug Administration (FDA) in 2014 to propose including the WP under its regulatory
authority, allowing the FDA to apply evidence-based regulatory approaches to control WP spread
in the US. Given the salience of flavored tobacco in shaping the “WP experience”, regulating WP
tobacco flavor represents a promising approach for the FDA to curb WP use among US youth.
This project aims to assist the FDA in these efforts by providing answers to specific questions
pertinent to the potential of WP regulation through flavor. These include: - How would flavor
manipulation affect the smoking experience and satisfaction of WP users at different stages of
their smoking trajectory - How would smoking non-preferred flavor or unflavored WP tobacco
reflects on smokers' exposure to nicotine, and dependence; and - How would flavor manipulation
influence puffing behavior and exposure to toxicants such as carbon monoxide (CO) among WP
smokers. Answers to these questions will help the FDA predict the impact of flavor regulation on
WP experimentation and continued use. In this study, we will use clinical laboratory methods to
answer these questions, where we will recruit two groups of WP smokers based on their use
frequency: low (Beginners) vs. high frequency (Experienced) smokers (72/group; total 144; age
18-30). Each participant will undergo 3 WP smoking sessions that differ by flavor (preferred flavor;
non-preferred flavor; unflavored), while measurement of WP satisfaction, dependence, harm
perception, and exposure to nicotine and toxicants will be conducted. The response of WP
smokers at different stages of their WP smoking trajectory (Beginners vs. Experienced) to flavor
manipulation, will allow us to predict the effect of limiting flavors on a wide range of WP smokers.
This project promises to provide the first evidence to guide the FDA in terms of the potential of
regulating WP flavored tobacco on WP uptake and use in the US.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
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批准号:10444519
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项目类别:
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资助金额:$51.05万
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财政年份:2022
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负责人:Wasim Maziak
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依托单位:
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资助金额:$40.22万
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批准号:8332504
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资助金额:$32.61万
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财政年份:2012
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Advancing addiction research and capacity to guide tobacco control in the Eastern
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批准号:9316565
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资助金额:$30.63万
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财政年份:2012
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负责人:Wasim Maziak
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依托单位:
Advancing addiction research and capacity to guide tobacco control in the Eastern
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批准号:8526443
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项目类别:
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资助金额:$30.58万
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财政年份:2012
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负责人:Wasim Maziak
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依托单位:
Advancing addiction research and capacity to guide tobacco control in the Eastern
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批准号:9117533
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项目类别:
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资助金额:$30.3万
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财政年份:2012
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负责人:Wasim Maziak
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依托单位:
Responding to the changing tobacco epidemic in the Eastern Mediterranean Region
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项目类别:
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资助金额:$30.43万
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财政年份:2007
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负责人:Wasim Maziak
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依托单位:
Responding to the changing tobacco epidemic in the Eastern Mediterranean Region
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批准号:7925647
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项目类别:
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资助金额:$30.02万
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财政年份:2007
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负责人:Wasim Maziak
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依托单位:
Responding to the changing tobacco epidemic in the Eastern Mediterranean Region
-
批准号:8133035
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项目类别:
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资助金额:$36.72万
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财政年份:2007
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负责人:Wasim Maziak
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依托单位:
Responding to the changing tobacco epidemic in the Eastern Mediterranean Region
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批准号:7292984
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项目类别:
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资助金额:$31.03万
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财政年份:2007
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负责人:Wasim Maziak
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依托单位:
Responding to the changing tobacco epidemic in the Eastern Mediterranean Region
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批准号:7679066
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资助金额:$30.44万
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财政年份:2007
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依托单位:
海外基金