Consortium Core

联合体核心 针对3个级别影响的干预措施似乎非常适合慢性病的研究和治疗， 它的起源几乎总是多因素的。然而，最近的一项文献回顾发现，仅发表了12篇 旨在缩小健康差距的多层次干预措施提供了足够的数据，以得出量化的 估计干预措施对健康结果的影响。只有6个是随机对照试验；没有一个 主要集中在血压控制上。由于实施是多水平试验的主要障碍， 选择学术和社区合作伙伴是成功实施多层次方案的关键 对未得到充分服务的群体进行干预。本土化控制高血压与科技风险 (本地图表)计划将不限于我们干预项目中的研究人员和当地合作伙伴。 相反，我们将建立一个由7个卫星中心组成的全国性网络，帮助教育、实施、 传播、政策和宣传倡议对我们的最终成功至关重要。外展、接洽和 传播委员会和指导委员会，NIMHD的科学工作人员将在其中发挥关键作用 确保地方、地区和国家社区参与需求评估、项目规划和设计， 执行和传播成果。我们的具体目标是：1)计划、实施和评估 参与和协作活动，以扩展我们的网络并解决与以下相关的优先事项 美国印第安人，阿拉斯加原住民， 和夏威夷土著/太平洋岛民；2)通过以下方式让利益攸关方更充分地参与研究过程 卫星中心和通信基础设施，包括年度会议，以优化利用 在地方、区域和国家各级进行有效干预；3)与卫星中心和方法合作 核心，进行与高血压相关的年度评估，以确定相关的地方、地区和国家 需求和优先事项；4)以传播为核心，促进科学严谨和文化知情 获取、应用和传播预防和治疗高血压知识的计划， 心血管疾病、中风及其危险因素--有望改善 我们感兴趣的人群；以及5)与社区和管理机构合作，实施或 加强法规和政策，促进社区和学术界之间的研究伙伴关系 并保护前者不受伤害。这一核心将成为多水平干预研究的焦点 关于美洲印第安人、阿拉斯加原住民和夏威夷原住民/太平洋岛民中的高血压。

CONSORTIUM CORE Interventions that target 3 levels of influence appear well-suited to the study and treatment of chronic diseases, the origins of which are virtually always multifactorial. However, a recent literature review found only 12 published multilevel interventions aimed at reducing health disparities provided enough data to derive a quantitative estimate of the intervention’s effect on health outcomes. Only 6 were randomized, controlled trials; and none focused primarily on blood pressure control. Because implementation is a major obstacle in multilevel trials, the selection of academic and community partners is crucial to the successful implementation of multilevel interventions with underserved groups. The Native-Controlling Hypertension And Risks through Technology (Native-CHART) program will not be limited to the researchers and local partners in our Intervention Projects. Instead, we will build a nationwide network of 7 Satellite Centers that will assist in education, implementation, dissemination, policy, and advocacy initiatives critical to our ultimate success. The Outreach, Engagement, and Dissemination Committee and the Steering Committee, in which NIMHD scientific staff will play key roles, will ensure local, regional, and national community involvement in needs assessment, project planning and design, implementation, and dissemination of results. Our Specific Aims are to: 1) plan, conduct, and evaluate engagement and collaborative activities that expand our network and address the priorities pertaining to hypertension, cardiovascular disease, stroke and related risk factors among American Indian, Alaska Native, and Native Hawaiian/Pacific Islander people; 2) bring stakeholders more fully into the research process through the Satellite Centers and a communication infrastructure, including annual conferences, to optimize the uptake of effective interventions at local, regional, and national levels; 3) with the Satellite Centers and Methodology Core, conduct annual assessments pertinent to hypertension to determine relevant local, regional, and national needs and priorities; 4) with the Dissemination Core, promote a scientifically rigorous and culturally informed program that acquires, applies, and distributes knowledge for preventing and treating hypertension, cardiovascular disease, and stroke and its risk factors – one that holds promise for improving health equity for our populations of interest; and 5) collaborate with community and governing agencies to implement or strengthen regulations and policies to foster research partnerships between communities and academic institutions and protect the former from harm. This Core will be a focal point for multilevel intervention research on hypertension among American Indians, Alaska Natives, and Native Hawaiian/Pacific Islanders.