ShEEP Request for EasyRatioPro Cell Imaging System

ShEEP 请求 EasyRatioPro 细胞成像系统

• 批准号: 9211812
• 负责人: Shannon Stroud Glaser
• 金额: --
• 依托单位: OLIN TEAGUE VETERANS CENTER
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-05-01 至 2016-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9211812
• 关键词: Air; Area; Basic Science; Bread; Calcium ion; Cardiac Myocytes; Cell model; Cells; Computer software; Computers; Coupled; Cyan Fluorescent Protein; Data; Detection; Devices; Digital Computers; Disease; Energy Transfer; Equipment; Floor; Fluorescent Dyes; Frequencies; Funding; Fura-2; Gases; Glass; Healthcare; Heating; Image; Intracellular Signaling Proteins; Ions; Lead; Leg; Length; Life; Light; Lighting; Link; Measurement; Medical; Microscope; Monitor; Morbidity - disease rate; Mus; Oils; Output; Pathologic Processes; Perfusion; Phase; Photobleaching; Photometry; Photons; Physiologic pulse; Play; Population; Prevention; Procedures; Proteins; Protons; Pump; Research; Research Personnel; Resolution; Sarcomeres; Scanning; Signal Transduction; Site; Source; Speed; Staging; Surface; System; Time; Tissue Model; Tissues; Training; Vacuum; Vendor; Veterans; Work; Xenon; analog; cell type; cellular imaging; computerized; design; digital; fluorescence microscope; imaging platform; imaging system; microscopic imaging; molecular imaging; mortality; new technology; novel therapeutics; potassium ion; prevent; programs; public health relevance; ratiometric; research study; response; sodium ion; solid state; vibration; voltage

PROJECT SUMMARY Basic science VA investigators at our facility require the use of cell models for their research programs. This application is a request for the EasyRatioPro Imaging Platform. This is an integrated “turnkey” system will be able to monitor intracellular signaling mechanisms in the cell and tissue models investigated in VA funded projects. In summary, this system will enhance the capability of our research center to better understanding of underlying mechanisms responsible for the pathological conditions that lead to significant mortality and morbidity in the Veteran population.

项目总结