Prevention of weight regain (POWeR) and cognitive funtion

预防体重反弹（POWeR）和认知功能

• 批准号: 9133369
• 负责人: Amanda N. Szabo-Reed
• 金额: $ 6万
• 依托单位: UNIVERSITY OF KANSAS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-01 至 2017-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9133369
• 关键词: Address; Adherence; Adult; Aerobic Exercise; Applications Grants; Area; Award; Body Weight Changes; Body Weight decreased; Clinical; Clinical Trials; Cognitive; Cognitive aging; Collection; Data; Data Analyses; Data Collection; Decision Making; Development; Diet; Dietary intake; Energy Intake; Exercise; Fellowship; Financial Support; Foundations; Funding; Future; Goals; Hand; Health; Health behavior; Individual; Intervention; Journals; K-Series Research Career Programs; Kansas; Knowledge; Manuscripts; Medical center; Mentorship; Obesity; Outcome; Overweight; Participant; Performance; Physical activity; Prevention; Protocols documentation; Publications; Randomized; Recommendation; Research; Research Design; Research Personnel; Research Project Grants; Resistance; Role; Solid; Techniques; Testing; Time; Training; Training Programs; United States National Institutes of Health; Universities; Weight; Weight maintenance regimen; Work; career; cognitive ability; cognitive performance; diet and exercise; executive function; exercise program; experience; improved; interest; meetings; post-doctoral training; programs; research study; responsible research conduct; sedentary; skills; weight loss intervention; weight maintenance

DESCRIPTION (provided by applicant): The applicant, Dr. Amanda Szabo, underwent graduate training in the area of physical activity (PA) cognitive performance and aging and is currently in post-doctoral training in weight management. Dr. Szabo has developed an interest in the impact of weight loss and maintenance on executive control in over weight and obese adults and is seeking dedicated training time to expand her experience in this area along with formal training in conducting weight management trials and data analysis for clinical trials research. Dr. Szabo and her mentorship team have identified a training plan to address gaps in her previous training. Dr. Szabo's training plan objectives include 1) obtaining hands on experience in clinical trial research focused on weight management (HL11842, PI - Donnelly) at the University of Kansas Medical Center, 2) gaining experience and training in collection and data analysis for clinical trial research along with specific training in techniques for analyzing executive performance data, 3) attending weekly investigator and journal club meetings to observe, discuss and participate in several ongoing NIH studies and have a dedicated venue to discuss current and future manuscripts/research grants, 4) participating in up to 7 professional development and clinical trial seminars each year and training in the responsible conduct of research, 5) developing 2 first-author manuscripts for publication each year, and 6) developing and completing a grant application (e.g., NIH K award - K99/R00). The POWeR study provides an excellent and timely opportunity for Dr. Szabo to add experiences that will further her development towards becoming an independent funded investigator conducting weight management interventions and assessing executive control. The F32 mechanism will support Dr. Szabo with dedicated time to advance her knowledge and skills in weight management interventions, the responsible conduct of research, study administration, data collection, research design, and advanced data analysis techniques for missing data and for clinical trials. In addition to these training experiences, Dr. Szabo has proposed unique areas of data collection and analysis previously not planned in the POWeR study. Dr. Szabo plans to 1) to determine how a typical weight loss program, consisting of diet and exercise, impacts executive control and 2) to determine how exercise and weight change over a 12 month weight maintenance period impacts executive control. Dr. Szabo's training to date will provide a solid foundation to build upon as she gains first- hand experience in areas where gaps in her training exist. The F32 award will provide the financial assistance and protected time necessary to successfully achieve these training objectives and provide a successful transition to independence.

描述（由申请人提供）：申请人 Amanda Szabo 博士接受过体力活动 (PA) 认知表现和衰老领域的研究生培训，目前正在接受体重管理方面的博士后培训。 Szabo 博士对减肥和维持体重对超重和肥胖成年人的执行控制的影响产生了兴趣，并正在寻求专门的培训时间来扩大她在该领域的经验，同时接受进行体重管理试验和临床试验研究数据分析的正式培训。萨博博士和她的导师团队已经制定了一项培训计划，以弥补她之前培训中的差距。 Szabo 博士的培训计划目标包括 1) 在堪萨斯大学医学中心获得专注于体重管理（HL11842，PI - Donnelly）的临床试验研究的实践经验，2) 获得临床试验研究收集和数据分析方面的经验和培训，以及分析执行绩效数据的技术方面的具体培训，3) 参加每周的研究者和期刊俱乐部会议，以观察、讨论和参与多项正在进行的 NIH 研究，并获得 讨论当前和未来手稿/研究资助的专用场所，4) 每年参加最多 7 场专业发展和临床试验研讨会，以及负责任的研究行为培训，5) 每年编写 2 篇第一作者手稿以供出版，以及 6) 制定并完成资助申请（例如 NIH K 奖 - K99/R00）。 POWeR 研究为 Szabo 博士提供了一个绝佳且及时的机会，以增加经验，这将进一步发展她成为一名独立资助的研究人员，进行体重管理干预措施和评估执行控制。 F32 机制将支持 Szabo 博士投入大量时间来提高她在体重管理干预措施、负责任的研究行为、研究管理、数据收集、研究设计以及针对缺失数据和临床试验的先进数据分析技术方面的知识和技能。除了这些培训经验之外，Szabo 博士还提出了以前在 POWeR 研究中未计划的独特的数据收集和分析领域。 Szabo 博士计划 1) 确定由饮食和运动组成的典型减肥计划如何影响执行控制；2) 确定 12 个月体重维持期内的运动和体重变化如何影响执行控制。萨博博士迄今为止所接受的培训将为她在培训中存在差距的领域获得第一手经验奠定坚实的基础。 F32 奖励将提供成功实现这些培训目标并成功过渡到独立所需的财务援助和受保护的时间。

项目成果

Distance learning strategies for weight management utilizing online social networks versus group phone conference call.

• DOI: 10.1002/osp4.96
• 发表时间: 2017-06
• 期刊: Obesity science & practice
• 影响因子: 2.2
• 作者: Willis EA;Szabo-Reed AN;Ptomey LT;Steger FL;Honas JJ;Al-Hihi EM;Lee R;Lee J;Oh Y;Washburn RA;Donnelly JE
• 通讯作者: Donnelly JE

Physical Activity, Fitness, Cognitive Function, and Academic Achievement in Children: A Systematic Review.

• DOI: 10.1249/mss.0000000000000901
• 发表时间: 2016-06
• 期刊: Medicine and science in sports and exercise
• 影响因子: 4.1
• 作者: Donnelly JE;Hillman CH;Castelli D;Etnier JL;Lee S;Tomporowski P;Lambourne K;Szabo-Reed AN
• 通讯作者: Szabo-Reed AN

Does the method of weight loss effect long-term changes in weight, body composition or chronic disease risk factors in overweight or obese adults? A systematic review.

• DOI: 10.1371/journal.pone.0109849
• 发表时间: 2014
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Washburn RA;Szabo AN;Lambourne K;Willis EA;Ptomey LT;Honas JJ;Herrmann SD;Donnelly JE
• 通讯作者: Donnelly JE

Do weight management interventions delivered by online social networks effectively improve body weight, body composition, and chronic disease risk factors? A systematic review.

• DOI: 10.1177/1357633x16630846
• 发表时间: 2017-02
• 期刊: Journal of telemedicine and telecare
• 影响因子: 4.7
• 作者: Willis EA;Szabo-Reed AN;Ptomey LT;Steger FL;Honas JJ;Washburn RA;Donnelly JE
• 通讯作者: Donnelly JE