Mindfulness Influences on Self-Regulation: Mental and Physical Health Implications

正念对自我调节的影响：心理和身体健康的影响

• 批准号: 9144313
• 负责人: Willoughby Britton
• 金额: $ 73.24万
• 依托单位: BROWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-15 至 2020-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9144313
• 关键词: Accounting; Address; Adherence; Adult; Affect; Alcohol consumption; Attention; Basic Science; Behavior; Behavior Therapy; Behavioral Assay; Beryllium; Biological Assay; Boxing; Characteristics; Chronic; Clinical; Clinical Psychology; Clinical Research; Clinical Services; Cognitive; Cognitive Science; Cohort Studies; Collection; Consensus; Data; Data Set; Diet; Discipline; Drug Prescriptions; Eating; Elements; Emotional; Evaluation; Goals; Grant; Health; Health behavior; Health behavior change; Health behavior outcomes; Hypertension; Informal Social Control; Intervention; Intervention Trial; Knowledge; Laboratories; Literature; Measures; Medial; Medical; Medicine; Mental Health; Meta-Analysis; Methods; Modeling; Modification; Neurosciences; Outcome; Performance; Phase; Population; Preventive Intervention; Primary Health Care; Process; Provider; Publications; Publishing; Qualitative Methods; Regimen; Research; Research Personnel; Resources; Risk Behaviors; Sampling; Science; Scientist; Services; Smoking; Staging; Testing; Time; Training; Translating; United States; United States National Institutes of Health; Universities; Variant; addiction; age group; base; behavior change; behavioral economics; clinically significant; design; effective therapy; emotion regulation; improved; medication compliance; member; mindfulness; mindfulness intervention; physical conditioning; physical inactivity; population health; primary care setting; psychologic; skills; therapy development; tool; working group

 DESCRIPTION (provided by applicant): The overarching goal of this grant is to use stages 0 and 1 of the NIH stage model to determine the extent to which various measures of self-regulation are assessing distinct or overlapping mechanisms involved in behavior change, and whether the measures perform similarly across populations, contexts, laboratories and age groups. The products of this project will be a systematic collection of validated and documented assays of specific self-regulation targets, and Mindfulness-Based Intervention (MBI) characteristics that engage those targets. These assays and tools will be shared with the field for incorporation in clinical studies and MBI development. Specifically, an interdisciplinary team of 12 basic science and clinical mindfulness researchers from 4 universities (Harvard, Brown, UMass, Georgetown) will (1) create a set of working groups that represent 3 domains of self-regulation (attention, emotion regulation, self-related processing), and (2) employ 4 sets of concurrent studies in order to complete the following aims: Aim 1: Identify putative self-regulation intervention targets by performing a comprehensive compilation and systematic evaluation of SR target performance in the existing (published) literature (Aim 1a) and from datasets belonging to MRC members or their networks (Aim 1b) using MacLeod and Clarke 2015's method of qualitative meta-analysis. Aim 2: Identify the conditions that affect (promote or inhibit) self-regulation target engagement, by comparing target performance across variations in assays, samples/conditions, and interventions (i.e. inter- assay validity and inter-laboratory reliability) (Aim 2a) and leveraging 4 sets of existing or ongoing trials that offer variations of targets, samples, health behaviors, and interventions to assess which conditions maximally engage self-regulation targets (Aim 2b) with resulting impacts on health behaviors and medical regimen adherence. Aim 3: Pilot-test the most promising self-regulation targets and intervention modifications gained from the first 2 phases by inserting them into two ongoing MBI trials for managing chronic medical conditions with 2 different treatment variations in 2 different settings. The Mindfulness-Based Hypertension Therapy (MBHT) study will assess self-regulation target engagement in a controlled research setting while the MINDFUL-Primary Care (PC) study will assess the same targets in a primary care setting with clinical service providers. Aim 4: Test the relationship between target engagement and medical regimen adherence and health behaviors in larger continuations of the MBHT and Mindful-PC studies. Aim 5: Bridge the science-to-service gap by disseminating the knowledge gained about high- (and low-) performing targets through collaborative publications, and by providing training to MBI service providers.

 描述（由申请人提供）：这项资助的总体目标是使用 NIH 阶段模型的阶段 0 和阶段 1 来确定各种自我调节措施在多大程度上评估涉及行为改变的不同或重叠机制，以及这些措施是否在不同人群、环境、实验室和年龄组中表现相似。该项目的产品将是对特定自我调节目标的经过验证和记录的分析的系统集合，以及涉及这些目标的基于正念的干预（MBI）特征。这些检测方法和工具将与该领域共享，以纳入临床研究和 MBI 开发。具体来说，由来自 4 所大学（哈佛大学、布朗大学、麻省大学、乔治敦大学）的 12 名基础科学和临床正念研究人员组成的跨学科团队将 (1) 创建一组代表自我调节 3 个领域（注意力、情绪调节、自我相关处理）的工作组，以及 (2) 采用 4 组并行研究来完成以下目标： 目标 1：通过执行全面的评估来确定假定的自我调节干预目标 使用 MacLeod 和 Clarke 2015 的定性荟萃分析方法，对现有（已发表）文献（目标 1a）以及属于 MRC 成员或其网络的数据集（目标 1b）对 SR 目标绩效进行汇编和系统评估。 目标 2：通过比较不同检测、样本/条件和干预措施的目标表现（即检测间有效性和实验室间可靠性）（目标 2a），并利用 4 组现有或正在进行的试验（提供目标、样本、健康行为和干预措施的变化）来评估哪些条件最大限度地参与自我调节目标，从而确定影响（促进或抑制）自我调节目标参与的条件（目标 2a）。 2b) 对健康行为和医疗方案依从性产生影响。 目标 3：通过将前两个阶段获得的最有希望的自我调节目标和干预修改插入到两个正在进行的 MBI 试验中进行试点测试，以在 2 个不同的环境中使用 2 种不同的治疗方案来管理慢性疾病。基于正念的高血压治疗（MBHT）研究将在对照研究环境中评估自我调节目标的参与情况，而正念初级保健（PC）研究将与临床服务提供者一起评估初级保健环境中的相同目标。 目标 4：测试 在 MBHT 和 Mindful-PC 研究的更大规模延续中，目标参与度与医疗方案依从性和健康行为之间的关系。 目标 5：通过合作出版物传播有关高（和低）绩效目标的知识，并为 MBI 服务提供商提供培训，从而弥合科学与服务之间的差距。