UCSF Nutrition Obesity Research Center

 描述(由申请人提供)：建议的加州大学旧金山分校NORC将整合多个营养、肥胖和新陈代谢领域的研究项目。在过去的12年里，加州大学旧金山分校积极扩大了在这一关键学科领域的研究基础。今天，这个研究基础非常强大，但其行政和设施基础设施反映了 扩大这一计划的部门流程的多样性。拟议的NORC将提供一个连贯的方案、行政和共享设施基础设施，将 整合加州大学旧金山分校已经很强大的营养、肥胖和新陈代谢研究，这将为其协调增长提供一个框架。加州大学旧金山分校NORC将包括细胞、动物、翻译、临床和流行病学方向。尽管有这种气息，但这些项目具有高度的互动性，即使是最不同的项目之间也有广泛的合作。例如，放射科医生与临床科学家合作，以非侵入性的方式观察人类的新陈代谢。人类遗传学家与细胞和动物研究人员合作，研究在这些系统中更容易处理的假说。行为科学家与营养学家协调，寻找改善结果的方法。总体而言，加州大学旧金山分校-NORC内的44名跨学科调查人员将由高级和早期调查人员组成，总共有60笔NIH补助金(总共100笔补助金)。他们的集体目标 将确定疾病的基本机制，并为预防和治疗肥胖症及其并发症作出重大贡献。加州大学旧金山分校-NORC的目的将是促进和发展加州大学洛杉矶分校和整个加州北部在肥胖、营养和新陈代谢方面的研究。这将通过以下方式实现：维持、改进和促进该领域内研究人员之间以及与该领域外研究人员之间的互动和合作。支持维护和发展最先进的研究核心，以满足肥胖、营养和新陈代谢研究的需求。通过试点和可行性机会，促进新研究方向的发展和新研究人员进入该领域。通过相关的教育论坛和其他支持发展和维持研究互动的场所，丰富NORC研究界。整合行政支持，确保基础设施满足当地肥胖、营养和新陈代谢研究社区的需求。

 DESCRIPTION (provided by applicant): The proposed UCSF NORC will integrate multiple research programs in multiple areas of nutrition, obesity and metabolism. Over the last twelve years, UCSF has actively expanded its research base in this critical subject area. Today, that research base is very robust but with an administrative and facilities infrastructure that reflects the diversity of the departmental processes that expanded this program. The proposed NORC will provide a cohesive programmatic, administrative and shared facilities infrastructure that will integrate the already strong nutrition, obesity and metabolism research conducted at UCSF and that will provide a framework for its coordinated growth. The UCSF NORC will include cellular, animal, translational, clinical and epidemiologic directions. Despite this breath, these programs are highly interactive with extensive collaborations amongst even the most divergent of programs. For example, radiologists collaborate with clinical scientists to non-invasively visualize metabolism in humans. Human geneticists collaborate with cellular and animal researchers to investigate hypotheses more tractable in those systems. Behavioral scientists coordinate with nutritionists to search for ways to improve outcomes. In all, the 44 interdisciplinary investigators within the UCSF-NORC will consist of a mixture of senior and early stage investigators with a collective 60 NIH grants (100 grants total). Their collective goal will be to define the underlying mechanisms of disease and to significantly contribute to the prevention and treatment of obesity and its complications. The purpose of the UCSF-NORC will be to promote and grow research in obesity, nutrition, and metabolism at UCSF and throughout northern California. This will be realized by: Maintaining, improving, and promoting the interactions and collaborations of researchers in the field with each other and with those outside the field. Supporting the maintenance and evolution of state-of-the-art Research Cores to meet the needs of obesity, nutrition, and metabolism research. Facilitating the development of new research directions and the entry of new researchers into the field via Pilot & Feasibility opportunities. Enriching the NORC research community through pertinent educational forums and other venues that support the development and maintenance of research interactions. Integrating administrative support to ensure that the infrastructure meets the needs of the local obesity, nutrition and metabolism research community.