UCSF Nutrition Obesity Research Center

 描述（由申请人提供）：拟议中的UCSF NORC将整合营养，肥胖和代谢多个领域的多个研究项目。在过去的12年里，UCSF积极扩大其在这一关键学科领域的研究基础。今天，该研究基地非常强大，但其行政和设施基础设施反映了 扩大该计划的部门流程的多样性。拟议的NORC将提供一个连贯的方案、行政和共享设施基础设施， 整合已经强大的营养，肥胖和代谢研究在加州大学旧金山分校进行，这将提供一个框架，其协调发展。UCSF NORC将包括细胞，动物，翻译，临床和流行病学方向。尽管如此，这些程序是高度互动的，即使是最不同的程序之间也有广泛的合作。例如，放射科医生与临床科学家合作，以非侵入性方式可视化人类的新陈代谢。人类遗传学家与细胞和动物研究人员合作，研究在这些系统中更容易处理的假设。行为科学家与营养学家合作，寻找改善结果的方法。总之，UCSF-NORC内的44名跨学科研究人员将由高级和早期研究人员组成，共有60名NIH赠款（共100赠款）。他们的共同目标 将是确定疾病的潜在机制，并大大有助于预防和治疗肥胖及其并发症。UCSF-NORC的目的是促进和发展UCSF和整个北方加州的肥胖、营养和代谢研究。这将通过以下方式实现：维护，改善和促进研究人员在该领域的相互作用和合作，并与那些外地。支持最先进的研究核心的维护和发展，以满足肥胖，营养和代谢研究的需求。促进新的研究方向的发展和新的研究人员进入该领域通过试点和可行性的机会。通过相关的教育论坛和其他支持发展和维持研究互动的场所丰富NORC研究社区。整合行政支持，以确保基础设施满足当地肥胖，营养和代谢研究社区的需求。

 DESCRIPTION (provided by applicant): The proposed UCSF NORC will integrate multiple research programs in multiple areas of nutrition, obesity and metabolism. Over the last twelve years, UCSF has actively expanded its research base in this critical subject area. Today, that research base is very robust but with an administrative and facilities infrastructure that reflects the diversity of the departmental processes that expanded this program. The proposed NORC will provide a cohesive programmatic, administrative and shared facilities infrastructure that will integrate the already strong nutrition, obesity and metabolism research conducted at UCSF and that will provide a framework for its coordinated growth. The UCSF NORC will include cellular, animal, translational, clinical and epidemiologic directions. Despite this breath, these programs are highly interactive with extensive collaborations amongst even the most divergent of programs. For example, radiologists collaborate with clinical scientists to non-invasively visualize metabolism in humans. Human geneticists collaborate with cellular and animal researchers to investigate hypotheses more tractable in those systems. Behavioral scientists coordinate with nutritionists to search for ways to improve outcomes. In all, the 44 interdisciplinary investigators within the UCSF-NORC will consist of a mixture of senior and early stage investigators with a collective 60 NIH grants (100 grants total). Their collective goal will be to define the underlying mechanisms of disease and to significantly contribute to the prevention and treatment of obesity and its complications. The purpose of the UCSF-NORC will be to promote and grow research in obesity, nutrition, and metabolism at UCSF and throughout northern California. This will be realized by: Maintaining, improving, and promoting the interactions and collaborations of researchers in the field with each other and with those outside the field. Supporting the maintenance and evolution of state-of-the-art Research Cores to meet the needs of obesity, nutrition, and metabolism research. Facilitating the development of new research directions and the entry of new researchers into the field via Pilot & Feasibility opportunities. Enriching the NORC research community through pertinent educational forums and other venues that support the development and maintenance of research interactions. Integrating administrative support to ensure that the infrastructure meets the needs of the local obesity, nutrition and metabolism research community.