Long-Term Care Research Network

摘要 候选人是加州大学医学、临床和翻译研究教授 匹兹堡，正在申请K07，以建立一个新的和新颖的计划，长期护理研究 网络(LTCRN)。长期护理(LTC)的居民是最虚弱和行动不便的，拥有最大 共同发病率和医疗保健系统的成本负担--然而很少有临床研究涉及这些 居民和健康老年人的实践指南可能并不相关。的长期目标是 这项综合性的临床调查和培训计划是为了增进老年人的健康 居住在长期护理设施中的成年人通过让研究人员参与相关和合作， 匹兹堡大学的多学科研究项目。短期目标是 该计划将建立必要的基础设施，以实现以下四个相互关联的目标 具体目标：1)在匹兹堡大学建立一个集中和综合的课程，并 匹兹堡大学医学中心(UPMC)汇聚多学科协作 专注于LTC研究以改善这些患者的健康的研究人员，2)形成了双重的 招聘模式，方便接触大匹兹堡的LTC居民和设施 愿意参与临床研究的地区，3)提供LTC流动实验室，以增强 将在每个LTC机构现场进行的临床研究，以及4)促进招募和 对对LTC研究感兴趣的年轻研究人员进行培训，以更好地了解 具体的LTC研究需求。她将通过开发LTCRN来实现这些目标 匹兹堡大学，利用UPMC老龄研究所的大量资源， 老年医学和老年病学部，临床翻译科学研究所和 临床研究教育，克劳德·佩珀老年美国独立中心(其中 她是PI)，大学里的许多培训项目，包括她自己的老年医学T32和 老年学、UPMC高级社区和许多知名的高级调查人员 目前在LTC环境下从事临床研究。这款K07的新颖组件包括 开发一个伞形计划，将多学科调查人员聚集在一起进行合作，a LTC参与者和设施登记处，一个流动实验室，允许调查人员现场提供 评估和针对学员和导师的个性化培训计划。候选人的 背景作为胡椒中心的PI和胡椒培训核心主任，NIA在 LTC研究，机构支持，以及10年的K24导师奖，为她提供了 领导技能、研究专业知识和经验，以实现一个成功和可持续的项目。

ABSTRACT The candidate, a Professor of Medicine and Clinical and Translational Research at the University of Pittsburgh, is applying for a K07 to establish a new and novel program, the Long-term Care Research Network (LTCRN). Long-term care (LTC) residents are the most frail and immobile, have the greatest co-morbidity and cost burden to the health care system -- yet little clinical research involves these residents, and practice guidelines for healthy elderly may not be relevant. The long-term objective of this comprehensive program of clinical investigation and training is to enhance the health of older adults residing in long-term care facilities by engaging researchers in relevant and collaborative, multidisciplinary research programs across the University of Pittsburgh. The short-term objective of the program is to build the infrastructure necessary to accomplish the following four interrelated specific aims: 1) Establish a centralized and integrated program at the University of Pittsburgh and University of Pittsburgh Medical Center (UPMC) bringing together multidisciplinary collaborative investigators who focus on LTC research to improve health for these patients, 2) Develop a dual recruitment model to facilitate access to both LTC residents and facilities in the greater Pittsburgh area who are willing to participate in clinical research, 3) Provide a LTC mobile laboratory to enhance clinical research that will be performed on site at each LTC facility, and 4) Promote recruitment and training for young investigators interested in LTC research to provide a better understanding of specific LTC research needs. She will accomplish these goals by developing the LTCRN at the University of Pittsburgh, leveraging the considerable resources of the UPMC Aging Institute, The Division of Geriatrics and Gerontology, The Clinical Translational Science Institute and Institute for Clinical Research Education, The Claude Pepper Older American Independence Center (of which she is the PI), the many training programs at the university including her own T32 in Geriatrics and Gerontology, UPMC Senior Communities and the many established senior investigators who are currently engaged in clinical research in the LTC setting. Novel components of this K07 include the development of an umbrella program to bring multidisciplinary investigators together to collaborate, a LTC participant and facility registry, a mobile laboratory to allow investigators to provide on-site evaluations and a personalized training program for both mentees and mentors. The candidate's background as the PI of the Pepper Center and Director of the Pepper training core, NIA funding in LTC research, institutional support, and 10 years of a K24 mentoring award, provides her with the leadership skills, research expertise and experience for a successful and sustainable program.