Using an API to commercialize an evidence-based weight loss intervention

使用 API 将基于证据的减肥干预措施商业化

• 批准号: 8926582
• 负责人: KATHLEEN Y WOLIN
• 金额: $ 57.59万
• 依托单位: COEUS HEALTH, LLC
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-15 至 2018-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8926582
• 关键词: Address; Attention; Behavioral; Blood Pressure; Body Weight decreased; Cellular Phone; Chronic Disease; Clinical; Computer software; Devices; Diet; Disease Management; Effectiveness; Electronic Health Record; Employee; Evidence based intervention; Glucose; Health; Health Risk Appraisals; Heart Diseases; Insurance Carriers; Intervention; Investigation; Language; Lipids; Location; Malignant Neoplasms; Manufacturer Name; Marketing; Metabolic syndrome; Non-Insulin-Dependent Diabetes Mellitus; Obesity; Online Systems; Outcome; Overweight; Participant; Patients; Phase; Physical activity; Plasma; Population; Process; Proteins; Randomized Clinical Trials; Randomized Controlled Trials; Research; Research Personnel; Resources; Risk Marker; Sampling; Services; Software Design; Swelling; Testing; Text; Time; Translating; Translations; Vendor; Weight; Weight maintenance regimen; Work; application programming interface; base; cardiometabolic risk; commercial application; commercialization; cost; cost effective; design; digital; effective intervention; effectiveness clinical trial; evidence base; experience; health application; mobile application; movie; psychosocial; theories; tool; usability; web app; weight loss intervention

DESCRIPTION (provided by applicant): Over 69 percent of the U.S. population is currently overweight or obese; 35 percent are obese. Obesity is a primary cause of numerous chronic diseases including type II diabetes, cancer, heart disease and the metabolic syndrome. Behavioral weight loss interventions have successfully resulted in significant clinical improvements in weight (7-10 percent weight loss) that is sustained for at least 6-12 months. Unfortunately, such interventions are often time consuming, resource intensive and difficult to scale. Digital health holds enormous promise for addressing weight loss and several trials have shown meaningful weight loss using digital health tools. Digital health provides a means of reaching large numbers of people with highly personalized content and sustained long-term participant engagement -all at low cost. Despite the promise, digital health has not delivered. Evidence-based tools are virtually absent from the commercial digital health space. This application creates a new commercial market segment for digital health - health application programming interfaces. An API is a way for software applications to talk to one another in a language that they both understand. APIs are efficient, cost effective, and ubiquitous in the commercial market. The API allows us to disseminate evidence based interventions in an efficient, cost-effective manner. APIs allow us to disseminate effective interventions in developer's "language," while preserving the interventions' theoretical and evidentiary basis. APIs are used anywhere that software is used, so they will allow us to reach varied health market segments including app developers, disease management firms, health insurers and employee wellness firms. In Phase I, we will create a commercial weight loss API (WeightBox) that builds on an existing evidence based framework and evaluate its usability. In Phase II, we will test the effectiveness of a mobile app that uses the WeightBox API in a randomized clinical trial. At the end of Phase II, our API (and proof-of-principle app) might be the only digital healt weight loss tools in the market with clinical trial effectiveness evidence.

描述（由申请人提供）：超过69%的美国人口目前超重或肥胖; 35%肥胖。肥胖是许多慢性疾病的主要原因，包括II型糖尿病、癌症、心脏病和代谢综合征。行为减肥干预已成功地导致体重的显著临床改善（体重减轻7- 10%），并持续至少6-12个月。不幸的是，这种干预措施往往耗费时间、资源密集，而且难以扩大规模。数字健康为解决减肥问题带来了巨大的希望，几项试验表明，使用数字健康工具可以实现有意义的减肥。数字健康提供了一种以高度个性化的内容和持续的长期参与者参与接触大量人群的方式-所有这些都是低成本的。尽管有这样的承诺，但数字健康并没有实现。基于证据的工具在商业数字健康领域几乎不存在。该应用程序为数字健康创建了一个新的商业细分市场-健康应用程序编程接口。API是软件应用程序以它们都能理解的语言相互交谈的一种方式。API是高效的，具有成本效益的，并且在商业市场上无处不在。API使我们能够以有效、具有成本效益的方式传播基于证据的干预措施。API使我们能够以开发人员的“语言”传播有效的干预措施，同时保留干预措施的理论和证据基础。API在任何使用软件的地方都可以使用，因此它们将使我们能够触及各种健康细分市场，包括应用程序开发人员、疾病管理公司、健康保险公司和员工健康公司。在第一阶段，我们将创建一个商业减肥API（WeightBox），建立在现有的证据为基础的框架，并评估其可用性。在第二阶段，我们将在随机临床试验中测试使用WeightBox API的移动的应用程序的有效性。在第二阶段结束时，我们的API（和原理证明应用程序）可能是市场上唯一具有临床试验有效性证据的数字健康减肥工具。