Behavioral outcomes and neurobiological mechanisms of sustained auditory selective attention
持续听觉选择性注意的行为结果和神经生物学机制
基本信息
- 批准号:10064026
- 负责人:
- 金额:$ 47.42万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-01-01 至 2024-12-31
- 项目状态:已结题
- 来源:
- 关键词:AcousticsAdoptedAdultAffectAnimal ExperimentationAnimalsAttentionAuditoryAuditory areaAutomobile DrivingBehaviorBehavioralBiological AssayCharacteristicsClinicalCognitiveCommunicationCommunication impairmentComplexCoupledCrowdingDevelopmental Communication DisordersDimensionsDiseaseElectrophysiology (science)Employment OpportunitiesEnvironmentEquilibriumEventFrequenciesFriendsFutureGoalsGrainHumanImpairmentLearningLifeLiteratureMagnetic Resonance ImagingMeasuresMental DepressionMental disordersModelingMolecularNeurobiologyNeurodegenerative DisordersNeurologicNoisePlayProcessPsychophysicsQuality of lifeResearchResolutionRestaurantsRiskSchoolsShapesSignal TransductionSocial isolationSourceSpeechStimulusStrokeTestingTrainingTraumatic Brain InjuryWorkWorkplaceauditory pathwaybehavioral outcomedevelopmental diseasedirected attentionevidence baseexpectationimprovedinnovationlecturesmeetingsmultimodalitymyelinationnervous system disorderneurobiological mechanismneuroimagingneuromechanismnovel strategiespreventremediationselective attentionsoundtheoriestool
项目摘要
PROJECT SUMMARY/ABSTRACT
Human communication and other listening behaviors often take place in acoustically complex, or noisy
environments like schools, restaurants, and workplaces. Much of daily life requires us to select behaviorally-
relevant auditory dimensions, and potentially suppress irrelevant dimensions, so that the information conveyed
can be remembered and responded to appropriately. Unfortunately, this vital everyday ability is affected by
many neurological conditions resulting in marked decreases in quality of life. Despite the importance of auditory
selective attention, its cognitive and neural mechanisms are poorly understood. For example, although auditory
selective attention is widely presumed to involve both a selective enhancement of behaviorally relevant auditory
dimensions and suppression of dimensions outside this attentional focus, evidence for suppression is scant. The
long-term goal of the proposed research is to arrive at a mechanistic understanding of auditory selective
attention. The present project pursues the central hypothesis that human auditory selective attention is a result
of processes related to both enhancement (of task-relevant sounds) and suppression (of task-irrelevant sounds).
Preliminary studies establish a nonspeech experimental paradigm for engaging - and improving –auditory
selective attention directed to specific frequency bands, and for non-invasively mapping it across auditory cortex
using multimodal MRI. A parallel preliminary study establishes that attention training drives improvements in
behavioral and electrophysiological measures of auditory selective attention. Aim 1 will determine the fine-
grained `listening window' through which auditory selective attention prioritizes and selects behaviorally
relevant auditory dimensions, and potentially suppresses irrelevant dimensions. These studies also will
determine the extent to which tasks and expectations created from input regularities shape the listening window.
Aim 2 will assess changes in the spectrotemporal shape of the auditory attentional filter as listeners learn to
more efficiently deploy auditory selective attention to specific dimensions. Aim 3 will identify the
neurobiological underpinnings of auditory selective attention and their changes across improvements in
selective attention. In all, the proposed research will weave together classic psychophysical approaches,
behavioral training as a means to introduce targeted demands on selective attention, and newly-developed
human neuroimaging tools to examine human auditory selective attention along the primary axis of auditory
representation – frequency. This will build a bridge from perceptuo-cognitive assays of human auditory selective
attention to mechanistic electrophysiological and cellular/molecular studies thus far only undertaken with
invasive nonhuman animal work, thereby compounding understanding and building a natural path toward
future evidence-based approaches to the remediation of auditory attention impairments.
项目总结/文摘
项目成果
期刊论文数量(0)
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专利数量(0)
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{{ truncateString('LORI L HOLT', 18)}}的其他基金
Behavioral outcomes and neurobiological mechanisms of sustained auditory selective attention
持续听觉选择性注意的行为结果和神经生物学机制
- 批准号:
10542666 - 财政年份:2020
- 资助金额:
$ 47.42万 - 项目类别:
Behavioral outcomes and neurobiological mechanisms of sustained auditory selective attention
持续听觉选择性注意的行为结果和神经生物学机制
- 批准号:
10319549 - 财政年份:2020
- 资助金额:
$ 47.42万 - 项目类别:
Behavioral outcomes and neurobiological mechanisms of sustained auditory selective attention
持续听觉选择性注意的行为结果和神经生物学机制
- 批准号:
10728405 - 财政年份:2020
- 资助金额:
$ 47.42万 - 项目类别:
Formation and tuning of complex auditory categories
复杂听觉类别的形成和调整
- 批准号:
7157583 - 财政年份:2001
- 资助金额:
$ 47.42万 - 项目类别:
Formation and Tuning of Complex Auditory Categories
复杂听觉类别的形成和调节
- 批准号:
8413771 - 财政年份:2001
- 资助金额:
$ 47.42万 - 项目类别:
Formation and Tuning of Complex Auditory Categories
复杂听觉类别的形成和调节
- 批准号:
7889685 - 财政年份:2001
- 资助金额:
$ 47.42万 - 项目类别:
Formation and Tuning of Complex Auditory Categories
复杂听觉类别的形成和调节
- 批准号:
8606118 - 财政年份:2001
- 资助金额:
$ 47.42万 - 项目类别:
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